Direct effect of chronic cyclosporine treatment on collagen III mRNA expression and deposition in rat kidneys

Clinical Nephrology

Volumn 53, Issue 4, 2000, Pages 8-9

  Ceol, M ^a   Anglani, F ^a   Vianello, D ^a   Murer, L ^a   Del Prete, D ^a   Forino, M ^a   Favaro, S ^a   Gambaro, G ^a   D'Angelo, A ^a  

^a UNIVERSITY OF PADOVA   (Italy)

Author keywords

Collagen III; CsA; Nephrotoxicity; Rats; RT PCR; TGF 1

Indexed keywords

COLLAGEN TYPE 3; CYCLOSPORIN; MESSENGER RNA; PLACEBO;

ANIMAL EXPERIMENT; ANIMAL MODEL; CONFERENCE PAPER; CONTROLLED STUDY; DRUG EXPOSURE; FIBROGENESIS; MALE; NEPHROTOXICITY; NONHUMAN; PATHOGENESIS; RAT; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; COLLAGEN; CYCLOSPORINE; IMMUNOSUPPRESSIVE AGENTS; KIDNEY; MALE; RATS; RATS, WISTAR; RNA, MESSENGER; TRANSFORMING GROWTH FACTOR BETA;

EID: 0034115166     PISSN: 03010430     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (4)

1. Andoh TF, Bennett WM 1998 Chronic cyclosporine nephrotoxicity. Curr Opin Nephrol Hypertens 7: 265-270
2. Ghiggeri GM, Altieri P, Oleggini R, Valenti F, Ginevri F, Perfumo F, Gusmano R 1994 Cyclosporine enhances the synthesis of selected extracellular matrix proteins by renal cells "in culture". Different cell responses and phenotype characterization. Transplantation 57: 1382-1388
3. 1 in mice: stimulation by cyclosporine. Transplantation 63: 1037-1039
4. Murer L, Giacomini A, Gambaro G, Del Prete D, Dall'Amico R, Pagetta E, Zacchello G, Anglani F 1998 Long-term treatment with CsA decreases INF-gamma mRNA and increases pre-pro-ET1 mRNA in rat kidneys. Transplant Proc 30: 950-951