Naphthazarin derivatives (IV): Synthesis, inhibition of DNA topoisomerase I and cytotoxicity of 2- or 6-acyl-5,8-dimethoxy-1,4- naphthoquinones

European Journal of Medicinal Chemistry

Volumn 35, Issue 3, 2000, Pages 291-298

  Song, Gyu Yong ^a   Kim, Yong ^a   Zheng, Xiang Guo ^a   You, Young Jae ^a   Cho, Hoon ^b   Chung, Jin Ho ^c   Sok, Dai Eun ^a   Ahn, Byung Zun ^a  

^a Chungnam National University   (South Korea)

^b Kuhnil Pharmaceutical Co LTD   (South Korea)

^c Seoul National University   (South Korea)

Author keywords

Cytotoxicity; DNA topoisomerase I inhibition; Naphthazarin; Structure activity relationship

Indexed keywords

1,4 NAPHTHOQUINONE DERIVATIVE; DNA TOPOISOMERASE; DNA TOPOISOMERASE INHIBITOR; NAPHTHAZARIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CHEMICAL STRUCTURE; CONTROLLED STUDY; CYTOTOXICITY; MOUSE; NONHUMAN; OXIDATION REDUCTION REACTION; OXYGEN CONSUMPTION; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

EID: 0034113785     PISSN: 02235234     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0223-5234(00)00129-X     Document Type: Article

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