Glycopyrrolate treatment of drooling in an adult male patient with cerebral palsy

Clinical and Experimental Pharmacology and Physiology

Volumn 27, Issue 4, 2000, Pages 320-322

  Neverlien, Per Otto ^a   Sorumshagen, L ^a   Eriksen, T ^a   Grinna, T ^a   Kvalshaugen, H ^a   Lind, A B ^a  

^a Modum Research Centre (MOREC)   (Norway)

Author keywords

Adult; Cerebral palsy; Drooling; Glycopyrrolate

Indexed keywords

GLYCOPYRRONIUM BROMIDE;

ADULT; CASE REPORT; CEREBRAL PALSY; DOSE RESPONSE; DRUG EFFECT; DRUG EFFICACY; DRUG SAFETY; HUMAN; HYPERSALIVATION; MALE; REVIEW;

CEREBRAL PALSY; GLYCOPYRROLATE; HUMANS; MALE; MIDDLE AGED; MUSCARINIC ANTAGONISTS; SIALORRHEA; TABLETS; TREATMENT OUTCOME;

EID: 0034112819     PISSN: 03051870     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1440-1681.2000.03099.x     Document Type: Review

References (26)

1. 1. Blasco PA, Allaire JH. Drooling in the developmentally disabled: Management practices and recommendations. Dev. Med. Child. Neurol. 1992; 34: 649-62.
2. 2. Neverlien PO. Treatment of drooling in cerebral palsy: A summary of the literature. Scand. J. Log. Phon. 1995; 20: 3-13.
3. 3. Crysdale WS. Management options for the drooling patient. Ear Nose Throat J. 1989; 68: 820-30.
4. 4. Brody GS. Control of drooling by translocation of parotid duct and extirpation of mandibular gland. Dev. Med. Child. Neurol. 1977; 19. 514-17.
5. 5. Rapp DL, Bowers PM. Meldreth dribble control project. Child Care Health Dev. 1979; 5: 143-9.
6. 6. Arnold HG, Gerdes J, Powers L. Transtympanic neurectomy: A solution to drooling problems. Dev. Med. Child Neurol. 1977; 19: 509-13.
7. 7. Guerin RL. Surgical management of drooling. Arch. Orolaryngol. 1979; 105: 535-7.
8. 8. Tonnby B. Transdermalt tilfoert skopolamin medel mot besvaerande draegling. Laekartidningen. 1987; 84: 612 (in Swedish).
9. 9. Talmi YP, Finkelstein Y, Zohar Y, Laurian N. Reduction of salivary flow with scopoderm TTS. Ann. Otol. Rhinol. Laryngol. 1988; 97: 128-30.
10. 10. Talmi YP, Finkelstein Y, Zohar Y. Reduction of salivary flow with transdermal scopolamine: A four-year experience. Otolaryngol. Head Neck. Surg. 1990; 103: 615-18.
11. 11. Rogawski MA. Transdermal scopolamine and sialorrhea. Arch. Neurol. 1984; 41: 15.
12. 12. Siegel LK, Klingbeil MA. Control of drooling with transdermal scopolamine in a child with cerebral palsy. Dev. Med. Child. Neurol. 1991; 33: 1013-14.
13. 13. Camp-Bruno JA, Winsberg BG, Green-Parsons AR, Abrams JP. Efficacy of benztropine therapy for drooling. Dev. Med. Child. Neurol. 1989; 31: 309-19.
14. 14. Reddihough D, Johnson H, Staples M, Hudson I, Exarchos H. Use of benzhexol hydrochloride to control drooling of children with cerebral palsy. Dev. Med. Child. Neurol. 1990; 32: 985-9.
15. 15. Bachrach S, Walter R, Trzcinski K. The use of glycopyrrolate for drooling in children with cerebral palsy. Dev. Med. Child. Neurol. 1995; 37 (Suppl. 13): 10.
16. 16. Blasco PA, Stansbury JCK. Glycopyrrolate treatment of chronic drooling. Arch. Ped. Adolesc. Med. 1996; 150: 932-5.
17. 17. Stern LM. Preliminary study of glycopyrrolate in the management of drooling. J. Paediatr. Child. Health. 1997; 33: 52-4.
18. 18. Ziskin AA. Transdermal scopolamine induced psychosis. Postgrad. Med. 1988; 84: 73-6.
19. 19. Cairncross JG. Scopolamine psychosis revisited. Ann. Neurol. 1983; 13: 582.
20. 20. Rodysill KJ, Warren JB. Transdermal scopolamine and toxic psychosis. Ann. Inter. Med. 1983; 98: 561.
21. 21. Osterholm RK, Camoriano JK. Transdermal scopolamine psychosis. J. Am. Med. Assoc. 1982; 247: 3081.
22. 22. Johnson SF, Moore RJ. Transderm pupil and confusion in a 10 year old. Ann. Neurol. 1983; 13: 583.
23. 23. Wilkinson JA. Side effects of transdermal scopolamine. J. Emerg. Med. 1987; 5: 389-92.
24. 24. Thomas-Stonell N, Greenberg J. Three treatment approaches and clinical factors in the reduction of drooling. Dysphagia 1988; 3: 73-8.
25. 25. Arneberg P, Storhaug K, Sandvik L. Effect of a slow release transcutaneous scopolamine application on salivary flow, pH, buffering action, and salivary levels of Streptococcus mutans and lactobacilli. Scand. J. Dent. Res. 1989; 97: 408-14.
26. 26. Arnrup K, Crossner C-G. Caries prevalence after submandibular duct reposition in drooling children with neurological disorders. Ped. Dent. 1990; 12: 98-101.