A single postoperative application of nitroglycerin ointment does not increase survival of cutaneous flaps and grafts

Dermatologic Surgery

Volumn 26, Issue 5, 2000, Pages 425-427

  Dünn, Gary L ^a,b   Brodland, David G ^b   Griego, Robert D ^b   Huether, Michael J ^b   Fazio, Michael J ^b   Zitelli, John A ^b  

^a UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^b NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCERYL TRINITRATE; POLYSPORIN; VASODILATOR AGENT;

ADULT; ARTICLE; CHEMOSURGERY; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; GRAFT SURVIVAL; HUMAN; MAJOR CLINICAL STUDY; POSTOPERATIVE CARE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SKIN FLAP; SKIN GRAFT; SKIN TRANSPLANTATION; TREATMENT OUTCOME;

EID: 0034112097     PISSN: 10760512     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1524-4725.2000.99307.x     Document Type: Article

References (8)

1. Kerrigan CL. Skin flap failure: pathophysiology. Plast Reconstr Surg 1983;72:766-74.
2. Needelman P, Corr PB, Johnson EM. Drugs used for the treatment of angina: organic nitrates, calcium channel blockers, and betaadrenergic antagonists. In: Gilman AG, et al., eds. The Pharmacological Basis for Therapeutics, 7th ed. New York: MacMillan, 1985; 806-26.
3. Rohrich RJ, Cherry GW, Spira M. Enhancement of skin-flap survival using nitroglycerine ointment. Plast Reconstr Surg 1984;76: 943-48.
4. Davis RE, Wachholz JH, et al. Comparison of topical anti-ischemic agents in the salvage of failing random-pattern skin flaps in rats. Arch Facial Plast Surg 1999;l:27-32.
5. Lehman RAW, Page RB, et al. Technical note: use of nitroglycerin ointment after precarious neurosurgical wound closure. Neurosurgery 1985;16:701-2.
6. Fan Z, Jinli H. Preventing necrosis of the skin flaps with nitroglycerine after radical resection for breast cancer. J Surg Oncol 1993;53: 210.
7. Scheuer S, Hanna MK. Effect of nitroglycerine ointment on penile skin flap survival in hypospadias repair. Urology 1986;28:438-40.
8. Nichter LS, Sobieski BA, Edgerton MT. Efficacy of topical nitroglycerine for random-pattern skin-flap salvage. Plast Reconstr Surg 1985;75:847-52.