Sympathetic and reflex alterations in systo-diastolic and systolic hypertension of the elderly

Journal of Hypertension

Volumn 18, Issue 5, 2000, Pages 587-593

  Grassi, Guido ^a,b   Seravalle, Gino ^b,c   Bertinieri, Giovanni ^b   Turri, Carlo ^b   Dell'Oro, Raffaella ^a   Stella, Maria Luisa ^b   Mancia, Giuseppe ^a,b,c  

^a SAN GERARDO HOSPITAL   (Italy)

^b FONDAZIONE IRCCS CA GRANDA OSPEDALE MAGGIORE POLICLINICO   (Italy)

^c ISTITUTO AUXOLOGICO ITALIANO   (Italy)

Author keywords

Baroreflex; Elderly; Hypertension; Isolated systolic; Sympathetic nervous system

Indexed keywords

NITROPRUSSIDE SODIUM; PHENYLEPHRINE;

ADRENERGIC SYSTEM; AGED; ARTERIAL PRESSURE; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; ESSENTIAL HYPERTENSION; FEMALE; GERIATRIC PATIENT; HEART RATE; HUMAN; MALE; PRESSORECEPTOR REFLEX; PRIORITY JOURNAL; SYMPATHETIC NERVE; SYMPATHETIC TONE; SYSTOLIC BLOOD PRESSURE;

EID: 0034111309     PISSN: 02636352     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004872-200018050-00012     Document Type: Article

References (39)

1. 1 Julius S, Pascual AV, London R. Role of parasympathetic inhibition in the hyperkinetic type of borderline hypertension. Circulation 1971; 44:413-418.
2. 2 Esler MD, Jennings G, Biviano B, Lambert G, Hasking G. Mechanisms of elevated plasma noradrenaline in the course of essential hypertension. J Cardiovasc Pharmacol 1986; 8 (suppl 5):539-544.
3. 3 Esler MD, Jennings G, Korner P, Willett I, Dudley F, Hasking G, et al. The assessment of human sympathetic nervous system activity from measurements of norepinephrine turnover. Hypertension 1988; 11:3-20.
4. 4 Esler MD, Lambert G, Jennings G. Regional norepinephrine turnover in human hypertension. Clin Exp Hypertens 1989; 11 (suppl 1):75-89.
5. 5 Ferrier C, Esler MD, Eisenhofer G, Wallin BG, Horne M, Cox HS, et al. Increased norepinephrine spillover into the jugular veins in essential hypertension. Hypertension 1992; 19:62-69.
6. 6 Anderson EA, Sinkey CA, Lawton WJ, Mark AL. Elevated sympathetic nerve activity in borderline hypertensive humans: evidence from direct intraneural recordings. Hypertension 1988; 14:1277-1283.
7. 7 Rea R, Hamdan M. Baroreflex control of muscle sympathetic nerve activity in borderline hypertension. Circulation 1990; 82:856-862.
8. 8 Matsukawa T, Gotoh E, Uneda S, Miyajima E, Shionoiri H, Tochikubo O, et al. Augmented sympathetic nerve activity in response to stressors in young borderline hypertensive men. Acta Physiol Scand 1991; 141:157-165.
9. 9 Matsukawa T, Mano T, Gotoh E, Ishii M. Elevated sympathetic nerve activity in patients with accelerated essential hypertension. J Clin Invest 1993; 92:25-28.
10. 10 Floras JS, Hara K. Sympathoneural and haemodynamic characteristics of young subjects with mild essential hypertension. J Hypertens 1993; 11:647-655.
11. 11 Grassi G, Cattaneo BM, Seravalle G, Lanfranchi A, Mancia G. Baroreflex control of sympathetic nerve activity in essential and secondary hypertension. Hypertension 1998; 31:68-72.
12. 12 Sundlof G, Wallin BG. Human muscle nerve sympathetic activity at rest: relationship to blood pressure and age. J Physiol Lond 1978; 274:621-637.
13. 13 Iwase S, Mano T, Watanabe T, Saito M, Kobayashi F. Age-related changes of sympathetic outflow to muscles in humans. J Gerontol 1991; 46:M1-M5.
14. 14 Ebert TJ, Morgan BJ, Barney JA, Denahan T, Smith JJ. Effects of aging on baroreflex regulation of sympathetic activity in humans. Am J Physiol 1992; 263:H798-H803.
15. 15 Ng AV, Callister R, Johnson DG, Seals DR. Age and gender influence muscle sympathetic nerve activity at rest in healthy humans. Hypertension 1993; 21:498-503.
16. 16 Esler MD, Turner AG, Kaye DM, Thimpson JM, Kingwell BA, Morris M, et al. Aging effects on human sympathetic neural function. Am J Physiol 1995; 268:R278-R285.
17. 17 Yamada Y, Miyajima E, Tochikubo O, Matsukawa T, Ishii M. Age-related changes in muscle sympathetic nerve activity in essential hypertension. Hypertension 1989; 13:870-877.
18. 18 Scherrer U, Randin D, Tappy L, Vollenweider P, Jequier E, Nicod P. Body fat and sympathetic nerve activity in healthy humans. Circulation 1994; 89:2634-2640.
19. 19 Grassi G, Seravalle G, Cattaneo BM, Bolla GB, Lanfranchi A, Colombo M, et al. Sympathetic activation in obese normotensive subjects. Hypertension 1995; 25:560-563.
20. 20 Grassi G, Seravalle G, Cattaneo BM, Lanfranchi A, Vailati S, Giannattasio C, et al. Sympathetic activation and loss of reflex sympathetic control in mild congestive heart failure. Circulation 1995; 92:3206-3211.
21. 21 Sanders JS, Ferguson DW. Diastolic pressure determines autonomic responses to pressure perturbation in humans. J Appl Physiol 1989; 66:800-807.
22. 22 Parati G, Casadei R, Groppelli A, Di Rienzo M, Mancia G. Comparison of finger and intra-arterial blood pressure monitoring at rest and during laboratory testing. Hypertension 1989; 13:647-655.
23. 23 Folland ED, Parisi AF, Moynihan PF, Jones DR, Feldman CL, Tow DE. Assessment of left ventricular ejection fraction and volumes by real-time, two dimensional echocardiography: a comparison of cineangiographic and radionuclide techniques. Circulation 1979; 60:760-766.
24. 24 Devereux RB, Reichek N. Echocardiographic determination of left ventricular mass in man. Circulation 1977; 55:613-618.
25. 25 Mancia G, Mark AL. Arterial baroreflex in humans. In: Shepherd JT, Abboud FM (editors): Handbook of physiology, section 2: The cardiovascular system. Bethesda, Maryland: American Physiological Society; 1983. pp. 755-793.
26. 26 Zimmerman BG. Evaluation of peripheral and central components of action of angiotensin on the sympathetic nervous system. J Pharmacol Exp Ther 1967; 158:1-10.
27. 27 Mancia G, Saino A, Grassi G. Interactions between the sympathetic nervous system and the renin-angiotensin system. In: Laragh J, Brenner B (editors): Hypertension: pathophysiology, diagnosis and management. New York, Raven Press; 1995. pp. 399-407.
28. 28 Landsberg L. Diet, obesity and hypertension: an hypothesis involving insulin, the sympathetic nervous system, and adaptive thermogenesis. QJ Med 1986; 236:1081-1090.
29. 29 Mark AL, Mancia G. Cardiopulmonary baroreflexes in humans. In: Shepherd JT, Abboud FM (editors): Handbook of physiology, section 2: The cardiovascular system. Bethesda, Maryland: American Physiological Society; 1983. pp. 795-813.
30. 30 Grassi G, Giannattasio C, Cleroux J, Cuspidi C, Sampieri L, Bolla GB, et al. Cardiopulmonary reflex before and after regression of left ventricular hypertrophy. Hypertension 1988; 12:227-237.
31. 31 Crane MG, Harris JJ. Effect of ageing on renin activity and aldosterone excretion. J Lab Clin Med 1976; 87:947-959.
32. 32 Fink RI, Kolterman OG, Griffin J, Olefsky JM. Mechanisms of insulin resistance in aging. J Clin Invest 1983; 71:1523-1535.
33. 33 Cleroux J, Giannattasio C, Bolla GB, Cuspidi C, Grassi G, Mazzola C, et al. Decreased cardiopulmonary reflexes with aging in normotensive humans. Am J Physiol 1989; 257:H961-H968.
34. 34 Giannattasio C, Seravalle G, Bolla GB, Cattaneo BM, Cleroux J, Cuspidi C, et al. Cardiopulmonary receptor reflexes in normotensive athletes with cardiac hypertrophy. Circulation 1990; 82:1222-1229.
35. 35 Takeshita A, Mark AL, Ekberg DL, Abboud FM. Effect of central venous pressure on arterial baroreflex control of heart rate. Am J Physiol 1979; 236:H42-H47.
36. 36 Esler M, Jennings G, Lambert G, Meredith I, Horne M, Eisenhofer G. Overflow of catecholamine neurotransmitters to the circulation: source, fate, and functions. Physiol Rev 1990; 70:963-985.
37. 37 Vaz M, Jennings G, Turner A, Cox H, Lambert G, Esler M. Regional sympathetic nervous activity and oxygen consumption in obese normotensive human subjects. Circulation 1997; 96:3423-3429.
38. 38 Grassi G, Vailati S, Bertinieri G, Seravalle G, Stella ML, Dell'Oro R, et al. Heart rate as a marker of sympathetic activity. J Hypertens 1998; 16:1635-1639.
39. 39 Folkow B, Svanborg A. Physiology of cardiovascular aging. Physiol Rev 1993; 73:725-764.