Anti-oxidant vitamins reduce normal tissue toxicity induced by radio- immunotherapy

International Journal of Cancer

Volumn 86, Issue 2, 2000, Pages 276-280

  Blumenthal, Rosalyn D ^a   Lew, Walter ^a   Reising, Albert ^a   Soyne, Danielle ^a   Osorio, Lou ^a   Ying, Zhiliang ^b   Goldenberg, David M ^a  

^a GARDEN STATE CANCER CENTER   (United States)

^b RUTGERS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOCOPHEROL; ASCORBIC ACID; RETINOL;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BONE MARROW SUPPRESSION; BONE MARROW TOXICITY; CONTROLLED STUDY; DOSE RESPONSE; MAXIMUM ALLOWABLE CONCENTRATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; RADIATION EXPOSURE; RADIOIMMUNOTHERAPY; VITAMIN INTAKE;

ANIMALS; ANTIOXIDANTS; ASCORBIC ACID; BODY WEIGHT; BONE MARROW DISEASES; BONE MARROW TRANSPLANTATION; COLONIC NEOPLASMS; HUMANS; INTESTINAL DISEASES; LEUKOCYTE COUNT; MICE; MICE, INBRED BALB C; MICE, NUDE; NEOPLASM TRANSPLANTATION; PLATELET COUNT; RADIOIMMUNOTHERAPY; VITAMIN A; VITAMIN E;

EID: 0034111015     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0215(20000415)86:2<276::AID-IJC19>3.0.CO;2-5     Document Type: Article

References (40)

1. BEHR, T.M., SHARKEY, R.M., SGOUROS, G., BLUMENTHAL, R.D., DUNN, R.M., KOLBERT, K., GRIFFITHS, G.L., SIEGEL, J.A., BECKER, W.S. and GOLDENBERG, D.M., Overcoming the nephrotoxicity of radiometal-labeled immunoconjugates: improved cancer therapy administered to a nude mouse model in relation to the internal radiation dosimetry. Cancer, 80, 2591-2610 (1997).
2. BLUMENTHAL, R.D., ALISAUSKAS, R., LEW, W., SHARKEY, R.M. and GOLDENBERG, D.M., Myelosuppressive changes from single or repeat doses of radioantibody therapy: effect of bone marrow transplantation, cytokines, and hematopoietic suppression. Exp. Hematol., 26, 859-868 (1999).
3. BLUMENTHAL, R.D., SHARKEY, R.M., FORMAN, D., WONG, G. and GOLDENBERG, D.M., Cytokine intervention permits dose escalation of radioantibody. An analysis of myelostimulation by bolus versus continuous infusion of I1-1/GM-CSF. Cancer, 73, 1083-1092 (1994).
4. BLUMENTHAL, R.D., SHARKEY, R.M., FORMAn, D., WONG, G., HESS, J. and GOLDENBERG, D.M., Improved experimental cancer therapy by radioantibody dose intensification as a result of syngeneic bone marrow transplantation. Exp. Hematol., 23, 1088-1097 (1995a).
5. BLUMENTHAL, R.D., SHARKEY, R.M. and GOLDENBERG, D.M., Dose escalation of radioantibody in a mouse model with the use of recombinant human interleukin-1 and granulocyte-macrophage colony-stimulating factor intervention to reduce myelosuppression [see comments]. J. Nat. Cancer Inst. 84, 399-407 (1992).
6. BLUMENTHAL, R.D., SHARKEY, R.M. and GOLDENBERG, D.M., Overcoming dose-limiting, radioantibody-induced myelotoxicity, pp. 295-314, CRC Press, Boca Raton, FL (1995b).
7. BLUMENTHAL, R.D., SHARKEY, R.M., HAYWOOD, L., BEHR, T. and GOLDENBERG, D.M., Application of cytokine intervention for improved radioantibody dose delivery. Int. J. Cancer, 72, 166-173 (1997).
8. DIPLOCK, A., Safety of antioxidant vitamins and beta-carotene. Amer. J. Coll. Nutr., (Suppl. 6), 1510S-1516S (1995).
9. FREI, B., Reactive oxygen species and antioxidant vitamins: mechanism of action. Amer. J. Med., 97, 5S-13S (1994).
10. HARAPANHALLI, R.S., NARRA, V.R., YAGHMAI, V., AZURE, M.T., GODDU, S.M., HOWELL, R.W. and RAO, D.V., Vitamins as radioprotectors in vivo. II. Protection by vitamin A and soybean oil against radiation damage caused by internal radionuclides. Rad. Res., 139, 115-122 (1994).
11. HARAPANHALLI, R.S., YAGHMAI, V., GIULIANI, D., HOWELL, R.W. and RAO, D.V., Antioxidant effects of vitamin C in mice following X-irradiation. Res. Comm. mol. Pathol. Pharmacol., 94, 271-287 (1996).
12. HAZUKA, M., EDWARDS-PRASAD, J., NEWMAN, F., KINZIE, J. and PRASAD, K., β-Carotene induces morphological differentiation and decreases adenylate cyclase activity in melanoma cells in culture. J. Amer. Coll. Nutr., 9, 143-149 (1990).
13. KAMINSKI, M.S., ZASADNY, K.R., FRANCIS, I.R., FENNER, M.C., ROSS, C.W., MILIK, A.W., ESTES, J., TUCK, M., REGAN, D., FISHER, S., GLENN, S.D. and WAHL, R.L., Iodine-131-anti-B1 radioimmunotherapy for B-cell lymphoma. J. clin. Oncol., 14, 1974-1981 (1996).
14. KESSINGER, A., ARMITAGE, J., LANDMARK, J., SMITH, D. and WEISEN-BURGER, D., Autologous peripheral blood stem cell transplantation restores hematopoietic function following marrow ablative therapy. Blood, 71, 2445-2450 (1988).
15. KLIMBERG, V., SALLOUM, R., KASPER, M., PLUMLEY, D., DOLSON, D., HAUTAMAKI, D., MENDENHALL, W., BOVA, F., BLAND, K., COPELAND, E., III, and SOUBA, W., Oral glutamine accelerates healing of the small intestine and improves outcome after whole abdominal radiation. Arch. Surg., 125, 1040-1045 (1990).
16. KONOPACKA, M., WIDEL, M. and RZESZOWSKA-WOLNY, J., Modifying effect of vitamins C, E, and beta carotene against gamma-ray-induced DNA damage in mouse cells. Mutation Res., 417, 85-94 (1998).
17. LANGMUIR, V.K. and SUTHERLAND, R.M., Radiobiology of radioimmunotherapy: current status. Antibody Immunoconj. Radiopharm., 1, 195-211 (1988).
18. MCCONAHEY, P. and DIXON, F., A method of trace radioiodination of proteins for immunologic purposes Int. Arch. Allergy, 27, 185-189 (1966).
19. NARRA, V.R., HOWELL, R.W., SASTRY, K.S. and RAO, D.V., Vitamin C as a radioprotector against iodine-131 in vivo. J. nucl. Med., 34, 637-640 (1993).
20. NIKI, E., NOGUCHI, N., TSUCHIHASHI, H. and GOTOH, N., Interaction among vitamin C, vitamin E, and beta-carotene. Amer. J. clin. Nutr., 62, 1322S-1326S (1995).
21. ORAZI, A., Du, X., YANG, Z., KASHAI, M. and WILLIAMS, D., Interleukin-11 prevents apoptosis and accelerates recovery of small intestinal mucosa in mice treated with combined chemotherapy and radiation. Lab. Invest., 75, 33-42 (1996).
22. PARK, C., Vitamin C in leukemia and preleukemia cell growth. Progr. clin. Biol. Res., 259, 321-330 (1988).
23. PRASAD, K.N. and KUMAR, R., Effect of individual antioxidant vitamins alone and in combination on growth and differentiation of human non-tumorigenic and tumorigenic parotid acinar cells in culture. Nutr. Cancer, 26, 11-19 (1996).
24. PRESS, O.W., APELBAUM, F.R., MARTIN, P., BADGER, C.C., NELP, W.B., GLENN, S., BUTCHKO, G., FISHER, D., PORTER, B., MATTHEWS, D.C., FISHER, L.D. and BERNSTEIN, I.D., Radiolabeled-antibody therapy of B-cell lymphoma with autologous bone marrow support. N. Engl. J. Med., 329, 1219-1224 (1993).
25. PRESS, O.W., EARY, J.F., APPELBAUM, F.R. and BERNSTEIN, I.D., Myeloablative radiolabeled antibody therapy with autologous bone marrow transplantation for relapsed B cell lymphomas. Cancer Treat. Res., 281-297 (1996).
26. ROSTOCK, R., STRYKER, J. and ABT, A., Evaluation of high dose vitamin E as a radioprotective agent. Radiology, 126, 763-765 (1980).
27. RUBIO, C. and JALNAS, M., Dose- and time-dependent histological changes following irradiation of the small intestine of rats. Digest. Dis. Sci., 41, 392-401 (1996).
28. SARMA, L. and KESAVAN, P.C., Protective effects of vitamins C and E against gamma-ray-induced chromosomal damage in mouse. Int. J. Radiat. Biol., 63, 759-764 (1993).
29. SCHWARTZ, J., Molecular and biochemical control of tumor growth following treatment with carotenoids or tocopherols, Humana Press, Totowa, NJ (1995).
30. SHARKEY, R.M. and 12 OTHERS, Clinical evaluation of tumor targeting with a high-affinity anti-carcinoembryonic antigen specific murine monoclonal antibody. MN-14. Cancer, 71, 2082-2096 (1993).
31. SIES, H. and STAHL, W., Vitamins E and C, β-carotene, and other carotenoids as antioxidants. Amer. J. clin. Nutr., 62, 1315S-1321S (1995).
32. STOYANOVSKY, D., GOLDMAN, R., DARROW, R., ORGANISCIAK, D. and KAGAN, V., Endogenous ascorbate regenerates vitamin E in the retina directly and in combination with dihydrolipoic acid. Curr. Eye Res., 14, 181-189 (1995).
33. SUBCOMMITTEE ON LABORATORY ANIMAL NUTRITION, NATIONAL RESEARCH COUNCIL, Nutrient requirements of laboratory animals, pp. 80-102, National Academy Press, Washington DC (1995).
34. TEICHER, B., SCHWARTZ, J., HOLDEN, S., ARA, G. and NORTHEY, D., In vivo modulation of several anticancer agents by beta-carotene. Cancer Chemother. Pharmacol., 34, 235-241 (1994).
35. + cells collected after granulocyte colony-stimulating factor plus chemotherapy-induced mobilization of peripheral blood stem cell [Letter]. Blood, 89, 4660-4661 (1997).
36. TOMA, S., LOSARDO, P., VINCENT, M. and PALUMBO, R., Effectiveness of β-carotene in cancer chemoprevention. Europ. J. Cancer Prevent., 4, 213-224 (1995).
37. UMEGAKI, K., ITOH, T. and ICHIKAWA, T., Effect of vitamin E on chromosomal damage in bone marrow cells of mice having received low doses of X-ray irradiation. Int. J. Vitam. Nutr. Res., 64, 249-252 (1994).
38. VRIESENDORP, H.M., QUADRI, S.M., ANDERSSON, B.S. and DICKE, K.A., Hematologic side effects of radiolabeled immunoglobulin therapy. Exp. Hematol., 24, 1183-1190 (1996).
39. YU, W., HEIM, K., QIAN, M., SIMMONS-MENCHACA, M., SANDERS, B.G. and KLINE, K., Evidence for role of transforming growth factor-B in RRR-alpha-tocopheryl succinate-induced apoptosis of human MDA-MB-435 breast cancer cells. Nutr. Cancer, 27, 267-278 (1997).
40. ZAMAN, Z., FIELDEN, P. and FROST, P., Simultaneous determination of vitamins A and E and carotenoids in plasma by reversed-phase HPLC in elderly and younger subjects. Clin. Chem., 39, 2229-2234 (1993).