PCBs, DDTs and methyl sulphone metabolites in various tissues of harbour porpoises from Swedish waters

Environmental Pollution

Volumn 110, Issue 1, 2000, Pages 29-46

  Karlson, K ^a   Ishaq, R ^a   Becker, G ^a   Berggren, P ^a   Broman, D ^a   Colmsjo A ^a  

^a STOCKHOLM UNIVERSITY   (Sweden)

Author keywords

GC MS AED; Harbour porpoise; Methyl sulphones of PCBs DDE; Organochlorines; Tissue distribution

Indexed keywords

1,1 DICHLORO 2,2 BIS(4 CHLOROPHENYL)ETHANE; 1,1 DICHLORO 2,2 BIS(4 CHLOROPHENYL)ETHYLENE; CHLORPHENOTANE; POLYCHLORINATED BIPHENYL;

BIOACCUMULATION; MARINE MAMMAL; MARINE POLLUTION;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ATOMIC EMISSION SPECTROMETRY; CHEMICAL ANALYSIS; EXTRACTION; GAS CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; NONHUMAN; PORPOISE; REVIEW; SWEDEN; TISSUE DISTRIBUTION; WATER POLLUTION;

NORTH SEA; SWEDISH COAST;

EID: 0034110315     PISSN: 02697491     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0269-7491(99)00283-3     Document Type: Article

References (77)

1. Aarefjord, H., Bjørge, A., Kinze, C.C., Lindstedt, I., 1996. Diet of the harbour porpoise Phocoena phocoena in Scandinavian waters. International Whaling Commision SC/45/SM3.
2. Aguilar A. Compartmentation and reliability of sampling procedures in organochlorine pollution surveys of cetaceans. Residue Reviews. 95:1985;91-114.
3. Ariyoshi N., Tanaka M., Ishii Y., Oguri K. Purification and characterization of dog liver mirosomal epoxide hydrolase. Journal of Biochemistry. 115:1994;985-990.
4. Bakke J.E., Bergman Å.L., Larsen G.L. Metabolism of 2,4′,5-trichlorobiphenyl by the mercapturic acid pathway. Science. 217:1982;645-647.
5. Bakke J., Bergman Å., Larsen G. Methylsulfone formation and PCB metabolism. Organohalogen Compounds. 25:1995;413-417.
6. Ballschmiter K., Zell M. Analysis of polychlorinated-biphenyls (PCB) by glass capillary gas chromatography. Composition of technical Aroclor and Clophen-PCB mixtures. Analytical Chemistry. 302:1980;20-31.
7. Berggren, P., 1992. Förslag till åtgärdsprogram för tumlare (Phocoena phocoena). Statens Naturvårdsverk (Rapport. Contract No. 410-3541-92).
8. Berggren, P., 1995. Stocks, Status and Survival of Harbour Porpoises in Swedish Waters. PhD thesis, Department of Zoology, Stockholm University, Sweden.
9. Berggren P., Arrhenius F. Sightings of harbour porpoises (Phocoena phocoena) in Swedish waters before 1990. Reports International Whaling Commission, Special Issue. 16:1995;99-107.
10. Berggren P., Arrhenius F. Densities and seasonal distribution of harbour porpoises (Phocoena phocoena) in the Swedish Skagerrak, Kattegat and Baltic Seas. Reports International Whaling Commission, Special Issue. 16:1995;109-121.
11. Berggren P., Ishaq R., Zebühr Y., Näf C., Bandh C., Broman D. Patterns and levels of organochlorines (DDTs, PCBs, non-ortho PCBs and PCDD/Fs) in male harbour porpoises (Phocoena phocoena) from the Baltic Sea, the Kattegat-Skagerrak Sea and west coast of Norway. Marine Pollution Bulletin. 38(12):1999;1070-1084.
12. Bergman Å., Athanasiadou M., Bergek S., Haraguchi K., Jensen S., Wehler E.K. PCB and PCB methyl sulfones in mink treated with PCB and various PCB fractions. Ambio. 21(8):1992;570-576.
13. Bergman Å., Nordstom R.J., Haraguchi K., Kuroki H., Béland P. PCB and DDE methyl sulfones in mammals from Canada and Sweden. Environmental Toxicology and Chemistry. 13:1994;121-128.
14. Bergman Å., Klasson-Wehler E., Kuroki H. Selective retention of hydroxylated PCB metabolites in blood. Environmental Health Perspectives. 102:1994;464.
15. Bjørge A., Hohn A.A., Kuam T., Lockyer C., Schweder T., Aarefjord H. Summary report from the harbour porpoise age determination workshop, Oslo, 21-23 May 1990. Reports International Whaling Commission, Special Issue. 16:1995;477-491.
16. Björn, H., 1999. Uptake, Turnover and Distribution of Chlorinated Fatty Acids in Aquatic Biota. PhD thesis, Lund University, Sweden.
17. Boon J.P., Oostingh I., van der Meer J., Hillebrand M.T.J. A model for the bioaccumulation of chlorobiphenyl congeners in marine mammals. Environmental Toxicology and Pharmacology. 270:1994;237-251.
18. Boon J.P., Reijnders P.J.H., Dols J., Wensvoort P., Hillebrand M.T.J. The kinetics of individual chlorinated biphenyl congeners in female harbour seals Phoca vitulina, with evidence for structure-related metabolism. Aquatic Toxicology. 10:1987;307-324.
19. Boon J.P., van der Meer J., Allchin C.R., Law R.J., Klungsøyr J., Leonards P.E.G., Spliid H., Storr-Hansen E., Mckenzie C., Wells D.E. Concentration-dependent changes of PCB patterns in fish-eating mammals: structural evidence for induction of cytochrome P450. Archives of Environmental Contamination and Toxicology. 33:1997;298-311.
20. Brandt I., Jönsson C.J., Lund B.O. Comparative studies on adrenocorticolytic DDT-metabolites. Ambio. 21:1992;602-605.
21. Brant I., Bergman Å. PCB methyl sulphones and related compounds: identification of target cells and tissues in different species. Chemosphere. 16(8/9):1987;1671-1676.
22. Bruhn R., Kannan N., Petrick G., Schulz-Bull D.E., Duinker J. CB pattern in the harbour porpoise: bioaccumulation, metabolism and evidence for cytochrome P450 IIB activity. Chemosphere. 31(7):1995;3721-3732.
23. Calambokidis J. Chlorinated Hydrocarbones in Harbour Porpoises from Washington, Oregon and California: Regional Differences in Pollutant Ratios (NMFS Administrative Report LJ-86-35C). 1986;Southwest Fisheries Center, La Jolla, CA.
24. Carlström, C., Berggren, P., Tumlaren och torskfisket. Rapport från observatörsprojektet våren 1995. Naturvårdsverket Rapport 4571.
25. De Guise S., Martineau D., Béland P., Fournier M. Possible mechanisms of action of environmental contaminants on St. Lawrence beluga whales (Delphinapterus leucas). Environmental Health Perspectives. 103(4):1995;73-77.
26. Eriksson U., Häggberg L., Kärsrud A.-S., Litzén K., Asplund L. Analytical Method for Determination of Chlorinated Organic Contaminants in Biological Matrices (ITM-rapport 59). 1997;Institute of Applied Environmental Research, Stockholm University.
27. Falandysz J., Yamashita N., Tanabe S., Tatsukawa R., Rucinska L., Skora K. Congener-specific data on polychlorinated biphenyls in tissues of common porpoise from Puck bay, Baltic Sea. Archives of Environmental Contamination and Toxicology. 26:1994;267-272.
28. Falandysz J., Dembowska A., Strandberg L., Strandberg B., Bergquist P.-A., Rappe C. PCBs in a pelagic food chain in the southern Baltic proper. Organohalogen. 39:1998;53-57.
29. Goksøyr A., Beyer J., Larsen H.E., Andersson T., Förlin L. Cytochrome P450 in seals: monooxygenase activities, immunochemical cross-reactions and response to phenobarbital treatment. Marine Environmental Research. 34:1992;113-116.
30. Granby K., Kinze C.C. Organochlorines in Danish and west Greenland harbour porpoises. Marine Pollution Bulletin. 22:1991;458-462.
31. Haraguchi K., Kuroki H., Masuda Y. Polychlorinated biphenyl methylsulfone congeners in human tissues: identification of methylsulfonyl dichlorobiphenyls. Chemosphere. 18 (1-6):1989;477-484.
32. Haraguchi K., Kuroki H., Masuda Y. Occurence and distribution of chlorinated aromatic methylsulfones and sulfoxides in biological samples. Chemosphere. 19 (1-6):1989;487-492.
33. Haraguchi K., Athanasiadou M., Bergman Å., Hovander L., Jensen S. PCB and PCB methyl sulfones in selected groups of seals from Swedish waters. Ambio. 21(8):1992;546-549.
34. Ishaq R., Karlson K., Näf C. Distribution of polychlorinated naphthalenes (PCNs) and non-ortho chlorinated biphenyls (PPCBs) in harbour porpoises (Phocoena phocoena) tissues. Organohalogen Compounds. 39:1998;161-164.
35. Janák K., Becker G., Colmsjö A., Östman C., Athanasiadou M., Valters K., Bergman Å. Methyl sulfonyl polychlorinated biphenyls and 2,2-bis(4-chlorophenyl)-1,1-dichlorethene in gray seal tissues determined by gas chromatography with electron capture detection and atomic emission detection. Environmental Toxicology and Chemistry. 17(6):1998;1046-1055.
36. Jensen S., Jansson B. Methyl sulfone metabolites of PCB and DDE. Ambio. 5:1976;257-266.
37. Jensen S., Johnels A.G., Olsson M., Otterling G. DDT and PCB in herring and cod from the Baltic, the Kattegat and the Skagerrak. Ambio, Special Report. 1:1972;71-85.
38. Jönsson C.J., Lund B.O. In vitro bioactivation of the environmental pollutant 3-methylsulphonyl-2,2-bis(4-chlorophenyl)-1,1-dichloroethene in the human adrenal gland. Toxicology Letters. 71:1994;169-175.
39. Kastelein R.A., van der Sijs S.J., Staal C., Nieuwstraten S.H. Blubber thickness in harbour porpoises (Phocoena phocoena). Read A.J., Wiepkema P.R., Nachtigall P.E. The Biology of the Harbour Porpoise. 1997;179-199 De Spil, Woerden, Netherlands.
40. Kato Y., Haraguchi K., Kawashima M., Yamada S., Masuda Y., Kimura R. Induction of hepatic microsomal drug-metabolizing enzymes by methylsulphonyl metabolites of polychorinated biphenyl congeners in rat. Chemico-Biological Interactions. 95:1995;257-268.
41. Kawai S., Fukushima M., Miyazaki N., Tatsukawa R. Relationship between lipid composion and organochlorine levels in the tissues of striped dolphine. Marine Pollution Bulletin. 19(3):1988;129-133.
42. Kleivane L., Skaare J.U., Bjorge A., de Ruiter E., Reijnders P.J.H. Organochlorine pesticide residue and PCBs in harbour porpoises (Phocoena phocoena), incidentally caught in Scandinavian waters. Environmental Pollution. 89:1995;137-145.
43. Koopman H.N. Topographical distribution of the blubber of harbour porpoise (Phocoena phocoena). Journal of Mammalogy. 79:1996;260-270.
44. Koopman H.N., Iverson S.J., Gaskin D.E. Stratification and age-related differences in blubber fatty acids of the male harbour porpoise (Pocoena phocoena). Journal of Comparative Physiology B, Biochemical, Systematic and Environmental Physiology. 165:1998;628-639.
45. Kuiken T., Bennet P.M., Allchin C.R., Kirkwood J.K., Baker J.R., Lockyer C.H., Walton M.J., Sheldrick M.C. PCBs, cause of death and body condition in harbour porpoises (Phocoena phocoena) from British waters. Aquatic Toxicology. 28:1994;13-28.
46. Kuiken T., Höfle U., Bennet P.M., Allchin C.R., Kirkwood J.K., Baker J.R., Appleby E.C., Lockyer C.H., Walton M.J., Sheldrick M.C. Adronocortical hyperplasis, disease, and chlorinated hydrocarbons in the harbour porpoise (Phocoena phocoena). Marine Pollution Bulletin. 26:1993;440-446.
47. Lamparski L.L., Nestrick T.J. Determination of tetra-, hexa-, hepta, and octachlorodibenzo-p-dioxin isomers in particulate samples at parts per trillion levels. Analytical Chemistry. 52:1980;2045-2054.
48. Larsen G.L., Bergman Å., Klasson-Wehler E., Bass N.M. A methylsulphonyl metabolite of a polychlorinated biphenyl can serve as a ligand for liver fatty acid binding protein in rat intestinal mucosa. Chemico-Biological Interactions. 77:1991;315-323.
49. Larsen G.L., Hakk H., Larsson C., Bergman Å. Interaction of 3-methylsulfonyl-2,2′,4′,5,5′,6-hexachlorobiphenyl with mammalian carrier proteins. Organohalogen Compounds. 37:1998;345-349.
50. Letcher, R.J., 1996. The Ecological and Analytical Chemistry of Chlorinated Hydrocarbone Contaminants and Methyl Sulfonyl-containing Metabolites in the Polar Bear (Ursus maritimus) food chain. PhD thesis, Carleton University, Ottawa, Ontario, Canada.
51. Letcher R.J., Norstrom R.J, Bergman Å. Geographical distribution and identification of methyl sulphone PCB and DDE metabolites in pooled polar bear (Ursus maritimus) adipose tissue from western hemisphere artic and sub articregions. The Science of the Total Environment. 160/161:1995;409-420.
52. Letcher R.J., Norstrom R.J, Bergman Å. An integrated analytical method for determination of polychlorinated aryl methyl sulfone metabolites and polychlorinated hydrocarbon contaminants in biological matrices. Analytical Chemistry. 67:1995;4155-4163.
53. Letcher R.J., Nordstom R.J., Muir D.C.G. Biotransformation versus bioaccumulation: sources of methyl sulfone PCB and 4,4′-DDE metabolites in the polar bear food chain. Environmental Science and Technology. 32(11):1998;1656-1661.
54. Letcher R.J., Muir D.C.G., Norstrom R.J., Michaud R., Beland P. PCB biotransformation and methyl sulfone PCB metabolites in beluga whale (Delphinapterus leucas) from the St. Lawrence river estuary and western Hudson Bay. Organohalogen Compounds. 33:1997;290-295.
55. Lockyer C. Aspects of the morphology, body fat condition and biology of the harbour porpoise, Phocoena phocoena, in British waters. Reports International Whaling Commission, Special Issue. 16:1995;199-209.
56. Lund B.-O., Bergman Å., Brandt I. Metabolic activation and toxicity of DDT-metabolite, 3-methylsulphonyl-DDE, in the adrenal zona fasciculata in mice. Chemico-Biological Interactions. 65:1988;25-40.
57. Lund B.-O., Örberg J., Bergman Å., Larsson C., Bergman A., Bäcklin B.-M., Håkansson H., Madej A., Brouwer A., Brunström B. Chronic and reproductive toxicity of a mixture of 15 methylsulfonyl-polychlorinated biphenyls and 3-methylsulfonyl-2,2-bis-(4-chlorophenyl)-1,1-dichloroethene in mink (Mustela vison). Environmental Toxicology and Chemistry. 18(2):1999;292-298.
58. Lund J., Nordlund L., Devereux T., Glaumann H., Gustafsson J.-Å. Physicochemical and immunochemical characterization of a binding-protein for PCB methyl sulfones. Chemosphere. 16(8/9):1987;1677-1680.
59. Moriarty F. Ecotoxicology. Exposure and residues. Moriarty F. Organochlorines Insecticides: Persistent Organic Pollutants. 1975;29 Academic Press, London.
60. Moriarty F. Terrestrial animals. Butler G.C. Principles of Ecotoxicology. 1978;169 Wiley, New York.
61. Muir D.G., Norstrom R.J., Simon M. Organochlorine contaminants in arctic marine food chains: accumulation of specific PCB congeners and chlordane-related compounds. Environmental Science and Technology. 22:1988;1071-1079.
62. Perrin, W.F., Donovan, G.P., Barlow, J. (Eds.), 1994. Gillnets and cetaceans. Reports International Whaling Commission, Special Issue 15, p. 629.
63. Preston B.D., Allen J.R. 2,2′,5,5′-tetrachlorobiphenyl: isolation and identification of metabolites generated by rat liver microsomes. Drug Metabolism and Disposition. 8:1980;197-204.
64. Preston B.D., Miller J.A., Miller E.C. Reactions of 2,2′,5,5′-tetrachlorobiphenyl-3,4-oxide with methionine, cysteine and glutathione in relation to formation of methylthio-metabolites of 2,2′,5,5′-tetrachlorobiphenyl in the rat and mouse. Chemico-Biological Interactions. 50:1984;289-312.
65. Schneider R. Polychlorinated biphenyls (PCBs) in cod tissues from the Western Baltic: significance of equilibrium partitioning and lipid composition in the bioaccumulation of lipophilic pollutants in gill-breathing animals. Meeresforsch. 29:1982;69-79.
66. Schulz D.E., Petrick G., Duinker J.C. Complete characterization of polychlorinated biphenyl congeners in commercial aroclor and clophen mixtures by multidimensional gas chromatography-electron capture detection. Environmental Science and Technology. 23:1989;852-859.
67. Stegeman, J.J., Hahn, M.E., 1994. Biochemistry and molecular biology of monooxygenases: current perspectives on multiplicity, functions and regulations of cytochrome P450 in aquatic species. In: Ostrander, G.K., Malins, D.C. (Eds.), Biochemical, Cellular and Molecular Biological Perspectives in Aquatic Toxicology. Lewis Press, pp. 87-206.
68. Stein, E.J., Tilbury, K.L., Brown, D.W., Wigren, C.A., Meador, J.P., Robisch, P.A., Chan, S.-L., Varanasi, U., 1992. Intraorgan Distribution of Chemical Contaminants in Tissues of Harbour Porpoises (Phocoena phocoena) from the Northwest Atlantic (NOAA Technical Memorandum NMFS-NWFSC-3). NOAA.
69. Strandberg B., Bergqvist P.-A., Rappe C. Dialysis with semipermeable membranes as an efficient lipid removal method in the analysis of bioaccumulative chemicals. Analytical Chemistry. 70:1998;526-533.
70. Tanabe S., Watanabe S., Kan H., Tatsukawa R. Capacity and mode of PCB metabolism in small cetaceans. Marine Mammals Science. 4(2):1988;103-124.
71. Tanabe S., Madhusree B., Öztürk A.A., Tatsukawa R., Miyazaki N., Özdamar E., Aral O., Samsun O., Öztürk B. Isomer-specific analysis of polychlorinated biphenyls in harbour porpoise (Phocoena phocoena) from the Black sea. Marine Pollution Bulletin. 34(9):1997;712-720.
72. Tilbury K.L., Stein J.E., Meador J.P., Krone C.A., Chan S.-L. Chemical contaminants in harbour porpoises (Phocoena phocoena) from the north Atlantic coast: tissue concentrations and intra- and inter-organ distribution. Chemosphere. 34(9/10):1997;2159-2181.
73. Troisi G.M., Haraguchi K., Simmonds M.P., Mason C.F. Methyl sulphone metabolites of polychlorinated biphenyls (PCBs) in cetaceans from the Irish and Aegean Seas. Archives of Environmental Contamination and Toxicology. 35:1998;121-128.
74. Watanabe S., Shimada T., Nakamura S., Nishiyama N., Yamashita N., Tanabe S., Tatsukawa R. Specific profile of liver microsomal cytochrome P-450 in dolphin and whales. Marine Environmental Research. 27:1989;51-65.
75. Weistrand C., Norén K. Methylsulfonyl metabolites of PCB and DDE in human tissues. Environmental Health Perspectives. 105(6):1997;644-649.
76. Westgate A.J., Muir D.C.G., Gaskin D.E., Kingsle M.C.S. Concentrations and accumulation patterns of organochlorine contaminants in the blubber of harbour porpoises, Phocoena phocoena, from the coast of Newfounland, the Gulf of St. Lawrence and the Bay of Fundy/Gulf of Maine. Environmetal Pollution. 95(1):1997;105-119.
77. Wolkers J., Burkow I.C., Witkamp R.F., Lydersen C., Dahle S., Monshouwer M. Cytochrome P450 mediated enzyme activities in relation to congener specific PCB accumulation in arctic seals. Organohalogen Compounds. 37:1998;421-424.