Defibrotide in recurrent thrombotic thrombocytopenic purpura

Clinical and Applied Thrombosis/Hemostasis

Volumn 6, Issue 2, 2000, Pages 69-70

  Pogliani, Enrico Maria ^a   Perseghin, Paolo ^a   Parma, Matteo ^a   Pioltelli, Pietro ^a   Corneo, Gianmarco ^a  

^a SAN GERARDO HOSPITAL   (Italy)

Author keywords

Defibrinotide; Thrombotic Thrombocytopenic Purpura

Indexed keywords

ACETYLSALICYLIC ACID; DEFIBROTIDE; VINCRISTINE;

ADULT; ARTICLE; CASE REPORT; DISEASE COURSE; HUMAN; MALE; MICROVASCULATURE; PLASMAPHERESIS; PRIORITY JOURNAL; RECURRENT DISEASE; THROMBOCYTOPENIA; THROMBOTIC THROMBOCYTOPENIC PURPURA; TREATMENT OUTCOME;

EID: 0034110198     PISSN: 10760296     EISSN: None     Source Type: Journal    
DOI: 10.1177/107602960000600203     Document Type: Article

References (12)

1. Torok TJ, Holman RC, Chorba TL. Increasing mortality from thrombotic thrombocytopenic purpura in the United States: analysis of national mortality data 1968-1991. Am J Med 1995;50:84.
2. Rock GA, Shumak KH, Buskard NA, et al. Comparison of plasma exchange with plasma infusion in the treatment of thrombotic thrombocytopenic purpura: Canadian Apheresis Study Group. New Engl J Med 1991;325:393.
3. Sgarahotto D, Vianello F, Scano F, et al. Clinical and laboratoristic remission after cryosupernatant plasma exchange in thrombotic thrombocytopenic purpura. Haematologica 1998;83:569.
4. Rose M, Eldor A. High incidence of relapses in thrombotic thrombocytopenic purpura: clinical study of 38 patients. Am J Med 1987; 83:437.
5. Onundarson PT, Rowe JM, Heal JM, Francis CW. Response to plasma exchange and splenectomy in thrombotic thrombocytopenic purpura: a 10-year experience at a single institution. Arch Int Med 1992;152:791.
6. Ahn YS, Harrington WJ, Seelman RC, Eytel CS. Vincristine therapy of idiopathic and secondary thrombocytopenias. N Engl J Med 1974;291:376.
7. Udvardy M, Rak K. Cyclophosphamide for chronic relapsing thrombotic thrombocytopenic purpura. Lancet 1990;36:1508.
8. Spiekermann K, Wörmann B, Rumpf K, Hiddemann W. Combination chemotherapy with CHOP for recurrent thrombotic thrombocytopenic purpura. Br J Haematol 1997;97:544.
9. Ulutin ON. Antithrombotic effect and clinical potential of defibrotide. Semin Thromb Hemost 1993;19:186.
10. Bacher P, Kindel G, Walenga JM, Fareed J. Modulation of endothelial and platelet function by a polydeoxyribonucleotide derived drug "defibrolide": a dual mechanism in the control of vascular pathology. Thromb Res 1993;70:343.
11. Hamblin M, Powels R, Treleaven J, et al. Defibrotide for refractory thrombotic, thrombocytopenic purpura (TTP) after bone marrow transplantation. Blood 1996;88(suppl. 1):60b.
12. Salat C, Holler E, Kolb HJ, et al. Plasminogen activator inhibitor-1 confirms the diagnosis of hepatic veno-occlusive disease in patients with hyperbilirubinemia after bone marrow transplantation. Blood 1997;89:2184.