Reduced 1H-NMR visibility of creatine in isolated rat hearts

Magnetic Resonance in Medicine

Volumn 43, Issue 4, 2000, Pages 497-502

  Schneider, Jürgen ^a   Fekete, Elsbeth ^a   Weisser, Alexander ^a   Neubauer, Stefan ^a   Von Kienlin, Markus ^a,b  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

1H MRS; Absolute quantification; Creatine; Rat heart; Visibility

Indexed keywords

HIGH PRESSURE LIQUID CHROMATOGRAPHY; RELAXATION TIME; VISIBILITY;

ABSOLUTE QUANTIFICATION; CREATINE; ISOLATED RAT HEART; PHANTOM EXPERIMENT; RAT HEART; RELATIVE CONCENTRATION; WATER SUPPRESSION; ^1H-MRS;

RATS;

CREATINE; GLUCOSE;

ANIMAL TISSUE; ARTICLE; CELL COMPARTMENTALIZATION; CONTROLLED STUDY; HEART MUSCLE; HEART PERFUSION; ISOLATED HEART; MALE; MEASUREMENT; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; RELAXATION TIME; REPRODUCIBILITY; VISIBILITY;

EID: 0034108741     PISSN: 07403194     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1522-2594(200004)43:4<497::AID-MRM2>3.0.CO;2-M     Document Type: Article

References (27)

1. Blondet P, Albrand JP, von Kienlin M, Décorps M. Use of a rotating phase DANTE pulse for in vivo 1H NMR spectral editing with a single irradiation facility. J Magn Reson 1987;71:342-346.
2. Richards TL, Terrier F, Sievers RE, Lipton MJ, Moseley ME, Higgins CB. Lactate accumulation in ischemic- and anoxic-isulated rat hearts assessed by H-1 spectroscopy. Invest Radiol 1987;22:638-641.
3. Keller AM, Sorce DJ, Sciacca RR, Barr ML, Cannon PJ. Very rapid lactate measurement in ischemic perfused hearts using 1H MRS continuous negative echo acquisition during steady-state frequency selective excitation. Magn Reson Med 1988;7:65-78.
4. Yaniamoto M, Lee JD, Shimizu H, Kawasaki N, Hara A, Ishii Y, Nakamura T. Evaluation of post-ischemic invocardial metabolism by 1H-magnetic resonance spectroscopy in the rabbit heart. Jpn Circ J 1994; 58:707-712.
5. Zhao P, Storey CJ, Babcock EE, Malloy CR, Sherry AD. 1H NMR detection of lactate and alanine in perfused rat hearts during global and low pressure ischemia. Magn Reson Med 1995;33:53-60.
6. Richards T, Tscholakoff D, Higgins CB. Proton NMR spectroscopy in canine myocardial infarction. Magn Reson Med 1987;4:555-566.
7. Evanochko WT. Reeves RC, Sakai TT, Canby RC, Pohost GM. Proton NMR spectroscopy in myocardial ischemic insult. Magn Reson Med 1987;5:23-31.
8. Evanochko WT. NMR spectroscopic assessment of altered myocardial lipid metabolism. Invest Radiol 1989;24:973-975.
9. Bouchard A, Doyle M. Wolkowicz PE, Wilson R, Evanochko WT, Pohost GM. Visualization of altered myocardial lipids by 1H NMR chemical-shift imaging following ischemic insult. Magn Reson Med 1991;17: 379-389.
10. Straeter Knowlen IM, Evanochko WT, den Hollander JA, Wolkowicz PE, Balschi JA, Caulfield JB, Ku DD, Pohost GM. 1H NMR spectroscopic imaging of myocardial triglycerides in excised dog hearts subjected to 24 hours of coronary occlusion. Circulation 1996;93:1464-1470.
11. Stewart LC, Saunders JK, Deslauriers R, Bourgeois D, Nédélec J-FJ. Simultaneous measurement of both lipid and lactate in isolated rat hearts by 1H NMR spectroscopy. Magn Reson Med 1993;30:655-660.
12. den Hollander JA, Evanochko WT, Pohost GM. Observation of cardiac lipids in humans by localized 1H magnetic resonance spectroscopic imaging. Magn Reson Med 1994;32:175-180.
13. Ugurbil K, Petein M, Maidan R, Michurski S. Cohn JN, From AHL. High resolution proton NMR studies of perfused rat heart. FEBS Lett 1984; 167:73-78.
14. Unitt JF, Schrader J, Brunotte F, Radda GK, Seymour AM. Determination of free creatine and phosphocreatine concentrations in the isolated perfused rat heart by 1H- and 31P-NMR. Biochim Biophys Acta 1992; 1133:115-120.
15. Bottomley PA, Weiss RG, Non-invasive magnetic-resonance detection of creatine depletion in non-viable infarcted myocardium. Lancet 1998; 351:714-718.
16. Kreis R, Felblinger J, Jung B, Boesch C. In vivo 1H-MR spectroscopy of the human heart. MAGMA 1998;6:164-167.
17. von Kienlin M, Rösch C, Le Fur Y, Behr W, Roder F, Haase A, Horn M, Illing B, Hu K, Ertl G, Neubauer S. Three-dimensional 31P magnetic resonance spectroscopic imaging of regional high-energy phosphate metabolism in injured rat heart. Magn Reson Med 1998;39:731-741.
18. Horn M. Frantz S, Remkes H, Laser A, Urban B, Mettenleiter A, Schnackerz K, Neubauer S. Effects of chronic: dietary creatine feeding on cardiac energy metabolism and on creatine content in heart, skeletal muscle, brain, liver and kidney. J Mol Cell Cardiol 1998;30:277-284.
19. Neubauer S, Ingwall JS. Verapamil attenuates ATP depletion during hypoxia: 31P-NMR studies of the isolated rat heart. J Mol Cell Cardiol 1989;21:1163-1178.
20. Lowry OH, Rosebrough MJ, Farr AL, Randall RJ. Protein measurement with the foline reagent. J Biol Chem 1951;193:265.
21. Vanhamme L, van den Boogaart A. Van Huffel S. Improved method for accurate and efficient quantification of MRS data with use of prior knowledge. J Magn Reson 1997;129:35-43.
22. Savabi F. Free creatine available to the creatine phosphate energy shuttle in isolated rat atria. Proc Natl Acad Sci USA 1988;85:7476-7480.
23. Lee YCP, Visscher MB. On the state of creatine in heart muscle. Proc Natl Acad Sci USA 1961;47:1510-1515.
24. Kreis R, Boesch C. Localized 1H-MRS without water saturation: techniques and initial results for human brain and muscle. In: Proceedings of the 6th ISMRM, Sydney, Australia, 1998. p 24.
25. Dreher W, Norris DC, Leibfritz D. Magnetization transfer affects the proton creatine/phosphocreatine signal intensity: in vivo demonstration in the rat brain. Magn Reson Med 1994;31:81-84.
26. Kruiskamp MJ, de Graaf RA, van Vliet G, Nicolay K. The 1H-NMR signal of creatine/phosphocreatine shows a strong off-resonance magnetization transfer effect. MAGMA 1997;V(II):27.
27. Kruiskamp MJ, Nicolay K. Unraveling the magnetization transfer effect on the 1H signal of creatine in rat skeletal muscle. In: Proceedings of 7th Annual Meeting of ISMRM, Philadelphia, 1999. p 196.