Mild left ventricular hypertrophy in essential hypertension: Is it really arrhythmogenic?

American Journal of Hypertension

Volumn 13, Issue 4, 2000, Pages 340-345

  Gatzoulis, Kostas A ^a,b   Vyssoulis, Gregory P ^a   Apostolopoulos, Theodoros ^a   Delaveris, Polychronis ^a   Theopistou, Artemisia ^a   Gialafos, John H ^a   Toutouzas, Pavlos K ^a  

^a HIPPOKRATION HOSPITAL   (Greece)

^b NONE   (Greece)

Author keywords

Arrhythmias; Hypertension; Left ventricular hypertrophy

Indexed keywords

AMLODIPINE; LISINOPRIL;

ADULT; AGED; ANTIHYPERTENSIVE THERAPY; ARRHYTHMOGENESIS; ARTICLE; CARDIOVASCULAR RISK; CONTROLLED STUDY; DISEASE ASSOCIATION; ECHOCARDIOGRAPHY; ESSENTIAL HYPERTENSION; FEMALE; FOLLOW UP; HEART LEFT VENTRICLE HYPERTROPHY; HEART VENTRICLE ARRHYTHMIA; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; REMISSION; SIGNAL AVERAGED ELECTROCARDIOGRAPHY; SUDDEN DEATH;

ADULT; AGED; ARRHYTHMIA; ECHOCARDIOGRAPHY; ELECTROCARDIOGRAPHY, AMBULATORY; FEMALE; FOLLOW-UP STUDIES; HUMANS; HYPERTENSION; HYPERTROPHY, LEFT VENTRICULAR; MALE; MIDDLE AGED; PROSPECTIVE STUDIES;

EID: 0034108056     PISSN: 08957061     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0895-7061(99)00201-0     Document Type: Article

References (32)

1. National High Blood Pressure Education Program: The fifth report of the joint national committee on detection, evaluation and treatment of high blood pressure. National Heart, Lung and Blood Institute, 1993:NIH Publication 93-1088.
2. IPPPSH Collaborative Group: Cardiovascular risk and risk factors in a randomized trial of treatment based on the beta-blocker oxprenolol: the International Prospective Primary Prevention Study in Hypertension (IPPSH). J Hypertension 1995;3:379.
3. Kannel WB, Gordon T, Offutt D: Left ventricular hypertrophy by electrocardiogram: prevalence, incidence and mortality in the Framingham Study. Ann Intern Med 1969;71:89-105.
4. Kannel WB, Castelli WP, McNamara PM, McKee PA, Feinleib M: Role of blood pressure in the development of congestive heart failure: the Framingham Study. N Engl J Med 1972;287:781-787.
5. Kannel WB, Gordon T, Castelli WP, Margolis JR: Electrocardiographic left ventricular hypertrophy and risk of coronary heart disease. The Framingham study. Ann Intern Med 1970;72:813-822.
6. Borhani N: Left ventricular hypertrophy, arrhythmias and sudden death in systemic hypertension. Am J Cardiol 1987;60:131-181.
7. Vardas PE, Simandirakis EN, Parthenakis FI, Manios EG, Eleftherakis NG, Terzakis DE: Study of late potentials and ventricular arrhythmias in hypertensive patients with normal electrocardiograms. PACE 1994;17: 577-584.
8. Hammond IW, Devereux RB, Alderman MH, Lutas EM, Spitzer MC, Crowley JS, Laragh LH. The prevalence and correlates of echocardiographic left ventricular hypertrophy among employed patients with uncomplicated hypertension. J Am Coll Cardiol 1986;7: 639-650.
9. Devereux RB, de Simone G, Koren MJ, Roman MJ, Laragh JH: Left ventricular mass as a predictor of development of hypertension. Am J Hypertens 1991;4: 6035-6075.
10. Levy D, Garrison RJ, Savage DD, Kannel WB, Castelli WP: Prognostic implications of echocardiographically determined left ventricular mass in the Framingham Heart Study. N Engl J Med 1990;322:1561-1566.
11. Koren MJ, Devereux RB, Casali PN, Savage DD, Laragh JH: Relation of left ventricular mass and geometry to morbidity and mortality in uncomplicated essential hypertension. Ann Intern Med 1991;114:342-345.
12. Dahlof B, Dennert K, Hansson L: Reversal of left ventricular hypertrophy in hypertensive patients. A metanalysis of 109 treatment studies. Am J Hypertension 1992;5:95-100.
13. Schmieder RE, Messerli FH, Garavaglia GE, Nunez BD: Cardiovascular effects of verapamil in patients with essential hypertension. Circulation 1987;75:1030-1036.
14. Drayer JIM, Gardin JM, Weber MA, Aronow WS: Changes in ventricular septal thickness during diuretic therapy. Clin Pharmacol Ther 1982;32:283-288.
15. Sahn DJ, De Maria A, Kisslo J, Weyman A: Recommendations regarding quantitation in M-mode echocardiography: results of a survey of echocardiographic measurements. Circulation 1978;58:1072-1083.
16. Vyssoulis GP, Trikas AG, Paleologos AA, Toutouza MG, Toutouzas PK: Significance of blood pressure levels achieved with felodipine anti-hypertensive treatment on cardiovascular structure and function changes. J Hum Hyperten 1998;12:427-432.
17. Gatzoulis KA, Carlson MD, Biblo LA, Rizos I, Gialafos J, Toutouzas P, Waldo AL: Time domain analysis of the signal averaged electrocardiogram in patients with a conduction defect or a bundle branch block. Eur Heart J 1995;16:1912-1919.
18. Vyssoulis GP, Karpanou EA, Pitsavos CE, Skoumas JN, Paleologos AA, Toutouzas PK: Differentiation of β-blocker effects on serum lipids and apolipoproteins in hypertensive patients with normolipidaemic or dislipidaemic profiles. Eur Heart J 1992;13:1506-1513.
19. Karpanou EA, Vyssoulis GP, Georgoudi DG, Toutouza MG, Toutouzas PK: Ambulatory blood pressure changes in the menstrual cycle of hypertensive women. Significance of plasma renin activity values. Am J Hypertens 1993;6:654-659.
20. Devereux RB, Reichek N: Echocardiographic determination of left ventricular mass in man. Circulation 1977; 55:613-618.
21. Romhilt-Estes DW, Estes EH: A point score system for the ECG diagnosis of left ventricular hypertrophy. Am Heart J 1968;75:752-758.
22. Bigger JT: Identification of patients at high risk for sudden cardiac death. Am J Cardiol 1984;54:3D.
23. McLenachan JM, Henderson E, Morris KI, Dargie HJ: Ventricular arrhythmias in patients with hypertensive left ventricular hypertrophy. N Engl J Med 1987;317: 787-792.
24. Vester EG, Kuhls S, Ochiulet-Vester J, Vogt M, Strauer BE: Electrophysiological and therapeutic implications of cardiac arrhythmias in hypertension. Eur Heart J 1992;13(suppl D):70-81.
25. Aronow WS, Epstein S, Koenigsberg M, Schwartz KS: Usefulness of echocardiographic LVH, ventricular tachycardia and complex ventricular arrhythmias in predicting ventricular fibrillation or sudden cardiac death in elderly patients. Am J Cardiol 1988;62:1124-1125.
26. Messerli FH, Ventura HD, Elizardi DJ, Dunn FG, Frohlich ED: Hypertension and sudden death: increased ventricular ectopic activity in left ventricular hypertrophy. Am J Med 1984;77:18-22.
27. Messerli FH, Grodzicki T: Hypertension, left ventricular hypertrophy, ventricular arrhythmias and sudden death. Eur Heart J 1992;13(suppl D):66-69.
28. Lavie CJ, Nuner BD, Caravaglia GE, Messerli FH. Hypertensive concentric left ventricular hypertrophy: when is ventricular ectopic activity increased? South Med J 1988;81:696-700.
29. Panagides D, Amabile G, Deharo JC, Audebert C, Djiane P, Bory M: Late potentials in patients with hypertension. Arch Mal Coeur Vaiss 1990;83:1165-1168.
30. Brune S, Gonska BD, Fieischman C, Belles B, Belles G, Kreuzer H: Prevalence of late ventricular potentials in hypertensive patients. J Cardiovasc Pharmacol 1991; 17(suppl 2):S146-S147.
31. Bethge C, Motz W, v Hehn A, Strauer BE: Ventricular arrhythmias in hypertensive heart disease with and without heart failure. J Cardiovasc Pharm 1987; 10(suppl 6):119-128.
32. Pringle SD, Dunn FG, MacFarlane PW, McKillop JH, Lorimer AR, Cobbe SM: Significance of ventricular arrhythmias in systemic hypertension with left ventricular hypertrophy. Am J Cardiol 1992;69:913-917.