Ultrastructural immunolocalization of basic fibroblast growth factor in fibroblasts and extracellular matrix

Histochemistry and Cell Biology

Volumn 113, Issue 3, 2000, Pages 227-233

  Aktas, Gulhan ^a   Kayton, Robert ^b  

^a TRAKYA UNIVERSITY   (Turkey)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR; COLLAGEN FIBER; NUCLEAR PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL NUCLEUS; CELL ORGANELLE; EXTRACELLULAR MATRIX; FIBROBLAST; HUMAN; HUMAN CELL; HUMAN TISSUE; ISOTOPE LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RAT; TISSUE REPAIR; ULTRASTRUCTURE; WOUND HEALING;

ANIMALIA;

EID: 0034107521     PISSN: 09486143     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004180050442     Document Type: Article

References (36)

1. Arese M, Chen Y, Florkiewicz RZ, Gualandrris A, Shen B, Rifkin DB (1999) Nuclear activities of basic fibroblast growth factor: potentiation of low-serum growth mediated by natural or chimeric nuclear localization signals. Mol Biol Cell 10:1429-1444
2. Belford DA (1997) The mechanism of excisional fetal wound repair in vitro is responsive to growth factors. Endocrinology 138: 3987-3996
3. Brigstock DR, Sasse J, Klagsbrun M (1991) Subcellular distribution of basic fibroblast growth factor in human hepatoma cells. Growth Factors 4:189-196
4. Burgess WH, Maciag T (1989) The heparin binding (fibroblast) growth factor family of proteins. Ann Rev Biochem 58:575-606
5. Casscells W, Spir E, Sasse J, Klagsburn M, Allen P, Lee M, Calvo B, Chiba M, Haggroth L, Folkman J, Epstein SE (1990) Isolation, characterization, and localization of heparin-binding growth factors in the heart. J Clin Invest 85:433-441
6. Florkiewicz RZ, Majack RA, Buechler RD, Florkiewicz E (1995) Quantitative export of FGF-2 occurs through an alternative, energy dependent, non-ER/Golgi pathway. J Cell Physiol 162: 388-399
7. Giri D, Ropiquet F, Ittman M (1999) Alterations in expression of basic fibroblast growth factor (FGF) 2 and its receptor FGFR-1 in human prostate cancer. Clin Cancer Res 5:1063-1071
8. Gospodarowicz D, Ferrara N, Schweigerer L, Neufeld G (1987) Structural characterization and biological functions of fibroblast growth factor. Endocr Rev 8:95-114
9. Hughes RC (1997) The galectin family of mammalian carbohydrate-binding molecules. Biochem Soc Trans 25:1194-1198
10. Kardami E, Fandrich RR (1989) Basic fibroblast growth factor in atria and ventricles of the vertebrate heart. J Cell Biol 109: 1865-1875
11. Kirsner RS, Eaglstein WH (1993) The wound healing process. Dermatol Clin 11:629-640
12. Linder C, Bystrom P, Engel G, Auer G, Aspenblad U, Strander H, Linder S (1998) Correlation between basic fibroblast growth factor immunostaining of stromal cells and stromelysin-3 mRNA expression in human breast carcinoma. Br J Cancer 77: 941-945
13. McNeil PL, Muthukrishnan L, Warder E, D'Amore PA (1989) Growth factors are released by mechanically wounded endothelial cells. J Cell Biol 109:811-822
14. Mehul B, Hughes RC (1997) Plasma membrane targeting, vesicular budding and release of galectin 3 from the cytoplasm of mammalian cells during secretion. J Cell Sci 110:1169-1178
15. Menon RP, Hughes RC (1999) Determinants in the N-terminal domains of galectin-3 for secretion by a novel pathway circumventing the endoplasmic reticulum-Golgi complex. Eur J Biochem 264:569-576
16. Mignatti P, Morimoto T, Rifkin DB (1992) Basic fibroblast growth factor, a protein devoid of secretory signal sequence, is released by cells via a pathway independent of the endoplasmic reticulum-Golgi complex. J Cell Physiol 151:81-93
17. Moscatelli D, Presta M, Joseph-Silverstein J, Rifkin DB (1986) Both normal and tumor cells produce basic fibroblast growth factor. J Cell Physiol 129:273-276
18. Muthukrishnan L, Warder E, McNeil PL (1991) Basic fibroblast growth factor is efficiently released from a cytolsolic storage site through plasma membrane disruptions of endothelial cells. J Cell Physiol 148:1-16
19. Nakanishi Y, Kihara K, Mizuno K, Masamune Y, Yoshitake Y, Nishikawa K (1992) Direct effect of basic fibroblast growth factor on gene transcription in a cell-free system. Proc Natl Acad Sci USA 89:5216-5220
20. Ohtani H, Nakamura S, Watanabe Y, Mizoi T, Saku T, Nagura H (1993) Immunocytochemical localization of basic fibroblast growth factor in carcinomas and inflammatory lesions of the human digestive tract. Lab Invest 68:520-527
21. Qu Z, Liebler JM, Powers MR, Galey T, Ahmadi P, Huang X, Ansel JC, Butterfield JH, Planck SR, Rosenbaum JT (1995) Mast cells are a major source of basic fibroblast growth factor in chronic inflammation and cutaneous hemangioma. Am J Pathol 147:564-573
22. Qu Z, Kayton RJ, Ahmadi P, Liebler JM, Powers MR, Planck SR, Rosenbaum JT (1998) Ultrastructural immunolocalization of basic fibroblast growth factor in mast cell secretory granules: morphological evidence for bFGF release through degranulation. J Histochem Cytochem 46:1119-1128
23. Renko M, Quarto N, Morimoto T, Rifkin DB (1990) Nuclear and cytoplasmic localization of different basic fibroblast growth factor species. J Cell Physiol 144:108-114
24. Rich CB, Nugent MA, Stone P, Foster JA (1996) Elastase release of basic fibroblast growth factor in pulmonary fibroblast cultures in down regulation of elastin-gene transcription: a role for basic fibroblast growth factor in regulating lung repair. J Biol Chem 271:23043-23048
25. Richardson TP, Trinkaus-Randall V, Nugent MA (1999) Regulation of basic fibroblast growth factor binding and activity by cell density and heparan sulfate. J Biol Chem 274:13534-13540
26. Rifkin DB, Moscatelli D (1989) Recent developments in the cell biology of basic fibroblast growth factor. J Cell Biol 109:1-6
27. Root LL, Shipley GD (1991) Human dermal fibroblasts express multiple bFGF and a FGF proteins. In Vitro Cell Dev Biol 27A:815-822
28. Roth J, Taatjes DJ, Warhol MJ (1989) Prevention of non-specific interactions of gold labeled reagents on tissue sections. Histochemistry 92:47-56
29. Schulze-Osthoff K, Risau W, Vollmer E, Sorg C (1990) In situ detection of basic fibroblast growth factor by highly specific antibodies. Am J Pathol 137:85-92
30. Story MT (1989) Cultured human foreskin fibroblasts produce a factor that stimulates their growth with properties similar to basic fibroblast growth factor. In Vitro Cell Dev Biol 25: 402-408
31. Story MT, Livingston B, Baeten L, Swartz SJ, Jacobs SC, Begun FP, Lawson RK (1989) Cultured human prostate-derived fibroblasts produce a factor that stimulates their growth with properties indistinguishable from basic fibroblast growth factor. Prostate 15:355-365
32. Suzuki K, Kamel T, Hakamata Y, Kikukawa K, Shiota K, Takahashi M (1991) Basic fibroblast growth factor-like substance in nuclei of male germ cells undergoing meiosis. Proc Soc Exp Biol Med 198:728-731
33. Taipale J, Keski-Oja J (1997) Growth factors in extracellular matrix. FASEB J 11:51-59
34. Tessler S, Neufeld G (1990) Basic fibroblast growth factor accumulates in the nuclei of various bFGF-producing cell types. J Cell Physiol 145:310-317
35. Toda S, Nishimura T, Yamada S, Koike N, Yonemitsu N, Watanbe K, Matsumura S, Gartner R, Sugihara H (1999) Immunohistochemical expression of growth factors in subacute thyroiditis and their effects on thyroid folliculogenesis and angiogenesis in collagen gel matrix culture. J Pathol 188:415-422
36. Yabu M, Shinomura Y, Minami T, Matsuzawa Y (1993) Immunohistochemical localization of basic fibroblastic growth factor in the healing stage of mouse gastric ulcer. Histochemistry 100:409-413