Effect of ubidecarenone oral treatment on aerobic power in middle-aged trained subjects

Journal of Sports Medicine and Physical Fitness

Volumn 40, Issue 1, 2000, Pages 51-57

  Bonetti, A ^a   Solito, F ^a   Carmosino, G ^b   Bargossi, A M ^c   Fiorella, P L ^c  

^a UNIVERSITY OF PARMA   (Italy)

^b Sci Department Master Pharma Srl   (Italy)

^c UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

Aerobic power; Exercise; Oxidative stress; Purine nucleotides; Ubidecarenone

Indexed keywords

ADENOSINE PHOSPHATE; CARBON DIOXIDE; HYPOXANTHINE; INOSINE; LACTIC ACID; PLACEBO; PURINE NUCLEOTIDE; REACTIVE OXYGEN METABOLITE; UBIDECARENONE; XANTHINE; XANTHINE DEHYDROGENASE; XANTHINE OXIDASE;

ADULT; AEROBIC CAPACITY; ANAEROBIC THRESHOLD; ANTIOXIDANT ACTIVITY; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CYCLING; EXERCISE; EXERCISE TEST; EXHAUSTION; HUMAN; HUMAN EXPERIMENT; LIPID PEROXIDATION; LUNG MINUTE VOLUME; MALE; MITOCHONDRIAL RESPIRATION; NORMAL HUMAN; OXIDATIVE PHOSPHORYLATION; OXIDATIVE STRESS; OXYGEN CONSUMPTION; RANDOMIZED CONTROLLED TRIAL; SINGLE BLIND PROCEDURE; WORKLOAD;

ADULT; ANTIOXIDANTS; BICYCLING; EXERCISE; EXERCISE TOLERANCE; HUMANS; MALE; MIDDLE AGED; PHYSICAL FITNESS; SINGLE-BLIND METHOD; UBIQUINONE;

EID: 0034105928     PISSN: 00224707     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. Mitchell P. The vital protonmotive role of coenzyme Q. In: Folkers K, Littarru GP, Yamagami T, editors. Biomedical and clinical aspects of coenzyme Q. Amsterdam: Elsevier Science Publishers 1991:3-10.
2. Hiramatsu M, Velasco RD, Wilson DS, Packer L. Ubiquinone protects against loss of tocopherol in rat liver microsomes and mitochondrial membranes. Res Comm Chem Pathol Pharmacol 1991;72(2): 231-41.
3. Ozawa T. Formation of oxygen radicals in the electron transfer chain and antioxidant properties of coergyme Q. In: Lenaz G, editor. Coenzyme Q, biochemistry, bioenergetics and clinical applications of ubiquinone. Chichester: Wiley Publisher, 1985:441-56.
4. Sjodin B, Hellsten Y, Apple FS. Biochemical mechanism for oxygen free radical formation during exercise. Sports Med 1990;10(4): 236-54.
5. Popinigis J. Human skeletal muscle: Lactate derived superoxide radical and its possible role in induction of adaptation phenomena. Biol Sports 1989;6(3):25-30.
6. 10) in high level endurance runners. In: Corongiu F, Banni S, Dessi MA, Rice-Evans C, editors. Free radicals and antioxidants in nutrition. London: Richelieu Press 1993:63-74.
7. Kanter MM. Free radicals, exercise and antioxidant supplementation. Int J Sport Nutr 1994;4:205-20.
8. Kuppusamy P, Zweier JL. Characterization of free radical generation by xantine oxidase. J Biol Chem 1989;264:9880-4.
9. Saugstad OD, Gluck L. Plasma hypoxantine levels in new born infants. Aspecific indicator of hypoxia. J Perinat Med 1982;10:266-72.
10. Idstrom JP, Soussi B, Elender A, Bylund-Fellenius AC. Purine metabolism after in vivo ischemia and reperfusion in rat skeletal muscle. Am J Physiol 1990;258(6):1668-73.
11. 10) on the metabolic response to work. J Sports Med Phys Fitness 1989;29(1):57-62.
12. Guerra GP, Ballardini E, Lippa S, Oradei A, Littarru GP. Effetto della somministrazione di ubidecarenone sul consumo massimo di ossigeno e sulla performance fisica in un gruppo di giovani ciclisti. Med Sport 1987;40:359-64.
13. 10 on the impaired aerobic function in middle aged women without organic disease. In: Folkers K, Littarru GP, Yamagami T, editors. Biomedical and clinical aspects of coenzyme Q. Amsterdam: Elsevier Science Publishers 1991:535-40.
14. 10 on physical work capacity in athletes, sedentary people and patients with mitochondrial disease. In: Folkers K, Littarru GP, Yamagami T, editors. Biomedical and clinical aspects of coenzyme Q. Amsterdam: Elsevier Science Publishers 1991:541-5.
15. Vanfraechem JHP, Folkers K. Coenzyme Q10 and physical performance. In: Folkers K, Yamagami T, editors. Amsterdam: Elsevier/North Holland Biomedical Press 1981;3:235-41.
16. Modesti P, Carletti M, Lana G. Nuova energia per il mitocondrio. Sport e Medicina 1988;1:13-20.
17. 10 treatment in high level athletes. In: Folkers K, Littarru GP, Yamagami T, editors. Biomedical and clinical aspects of coenzyme Q. Amsterdam: Elsevier Science Publishers 1991:513-20.
18. 10 on the exercise tolerance of middle-aged, untrained men. Int J Sports Med 1995;16:421-7.
19. Ernster L, Forsmark-Andree P. Ubiquinol: An endogenous antioxidant in aerobic organism. Clin Invest 1993;71:s60-s5.
20. Beyer RE. The role of coenzyme Q in endurance training-acquired resistance to free radical damage. In: Folkers K, Littarru GP, Yamagami T, editors. Biomedical and clinical aspects of coenzyme Q. Amsterdam: Elsevier Science Publishers 1991:501-12.
21. Crane FL, Sun IL, Sun EE. The essential functions of coenzyme Q. Clin Invest 1993;71:s55-s9.
22. Burstein R, Franchel M, Kalmovitz B, Moran D, Epstein Y. Ubiquinone as a potential agent to minimize muscle membrane damage induced by exercise. Med Sci Sports Exerc 1995;27(5):s203.
23. 10 results in increased levels of ubiquinol-10 within circulating lipoproteins and increased resistance of human low-density lipoprotein to the initiation of lipid peroxidation. Bioch Biophys Acta 1992;1126:247-54.
24. Wasserman K, Hansen JE, Sue DY, Whipp BJ, Casaburi R. Principles of exercise testing and interpretation. Philadelphia: Lea & Fabiger, 1994:35,55,437.
25. Caiozzo VJ, Davis JA, Ellis JF, Azus JL, Vandagriff R, Prietto CA et al. A comparison of gas exchange indices used to detect the anaerobic threshold. J Appl Physiol Respirat Environ Exerc Physiol 1982;53:s1184-s9.
26. Bianchi GP, Grossi G, Chianese R, Marchesini G. Determinazione su plasma mediante cromatografia liquida ad alta pressione (HPLC) di nucleosidi e loro metaboliti. Clin Lab 1990;14:229-33.
27. Marbach EP, Weil MH. Rapid enzymatic measurement of blood lactate and piruvate. Clin Chem 1967;13:314-25.
28. 10 in plasma. J Chromat 1992;593:217-26.
29. Wyss V, Lubich T, Ganzit GP, Cesaretti D, Fiorella PL, Dei Rocini C et al. Remarks on prolonged ubiquinone administration in physical exercise. In: Lenaz G, Barnabei O, Rabbi A, Battino M, editors. Highlights in ubiquinone research. London-New York-Philadelphia: Taylor & Francis, 1990:303-6.
30. Poole D, Gaesser G. Response of ventilatory and lactate threshold to continuous and interval training. J Appl Physiol 1985;58(4): 1115-21.
31. 2 max and diastolic function in athletes. In: Folkers K, Littarru GP, Yamagami T, editors. Biomedical and clinical aspects of coenzyme Q. Amsterdam: Elsevier Science Publishers 1991:525-33.
32. 10 therapy for idiopathic dilated cardiomyopathy. Am J Cardiol 1990;65:521-2.
33. Mariani E, Galluccio A, Passafaro M, Guerriero T. Valutazione dell'influenza del trattamento cronico con ubidecarenone sulle possibilità prestative del corridore di maratona. Med Sport 1987; 40:297-301.