Study on the action of captopril: A sulfhydryl donor on rodent ulcer

Indian Journal of Pharmacology

Volumn 32, Issue 1, 2000, Pages 25-27

  Dau, Harminder ^a   Chauhan, C K ^a   Shahani, S ^a  

^a LOKMANYA TILAK MUNICIPAL GENERAL HOSPITAL   (India)

Author keywords

Captopril; Gastric ulcer; Omeprazole; Paracetamol; Sulfhydryl

Indexed keywords

CAPTOPRIL; OMEPRAZOLE; PARACETAMOL; THIOL DERIVATIVE;

ANIMAL MODEL; ARTICLE; DOSE RESPONSE; DRUG EFFECT; FEMALE; MALE; NONHUMAN; RAT; STOMACH PROTECTION; STOMACH ULCER;

EID: 0034105520     PISSN: 02537613     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. Ko JK, Cho CH. Role of non-protein sulfhydril compounds in gastric adaptive cytoprotection against ethanol-induced mucosal damage in rats. Inflamm Res 1995;44:242-4.
2. Szabo S, Szlenji S. Cytoprotection in gastro-intestinal pharmacology. TIPS 1987;8:149-54.
3. Salim AS. Protection against chronic ulceration in rat with sulfhydril containing agents. J Pharm Sci 1992;81:698-700.
4. Sushma AB, Joaquim SP, Shanta SH, Rosa SD. Effect of captopril on oxyphenbutazone and ethanol induced gastric lesions in rats. Euro J Pharmacol 1990;177:87-90
5. Rao SP, Sathiamoorthy A, Sathiamoorthy SS. Effect of angiotensin converting enzyme inhibitor captopril on gastric ulcer production in pylorus ligated rats Indian J Physiol Pharmacol 1995;36:296-8.
6. Im Wb, Blakeman DP, Sach G. Reversal of antisecretory activity of omeprazole by sulfhydryl compound in isolated rabbit gastric glands. Biochem Biophys 1985;845:54-9.
7. Loguercia C. Glutathion prevents ethanol induced gastric mucosal damage and depletion of sulfhydryl compounds in humans. Gut 1993;34:161-5.
8. Dadkar VN, Joshi AG, Jaguste VS, Billimoria FR, Dhar HL. Antistress activity of Oscimim sanctum (Tulsi). Indian Drugs 1988;25:172-5
9. Robert A, Nezamis JE, Lancaster C, Henchor AJ. Cytoprotection by prostaglandins in rats, prevention of gastric necrosis produced by alcohol, hydrochloric acid, sodium hydroxide, hypertonic sodium chloride and thermal injury. Gastroenterol 1979;77:433-43.
10. Dasgupta SR, Mukherjee BR Sinha M, Sahana CC. A study of the effect of Curcuma Longa (Linn) on experimental gastric ulcers in animals. Indian J Pharmacol 1969;1:49-54.
11. Rosa SD, Sushma AB, Vishwanath GD. Comparison of the effect of captopril and enalapril on oxyphenbutazone and ethanol induced gastric lesions in rats. Indian J Physiol Pharmacol 1990;31:206-8.
12. Ko JK, Cho CH. Histological study of mechanism of adaptive cytoprotection on ethanol induced mucosal damage in rat stomach Dig Dis Sci 1998;43:1248-57.
13. Bain SC, Leu Guen CA. Comparison of free radical scavenging activity of captopril versus enalapril. J Hum Hypertens 1991;516:511-5.
14. Jerry ST, Paul WF. Sulfhydryl compounds may mediate Cytoprotection. TIPS 1981;214:200-2.
15. Pihan G, Majzoubi D. Early microcirculatory injury in the rat and prevention by 16 dimethyl prostaglandin E2 or sodium thiosulfate. Gastroenterol 1986;91:1415-26.
16. Kaji T, Okada M, Nido H, Okabe S. Role of sulfhydyl in mucosal injury caused by ethanol in microvascular permeability, gastric motility and Cytoprotection. J Pharmacol Exp Therp 1984;248:856-9.