New aspects in genotoxic risk assessment of styrene exposure - A working hypothesis

Medical Hypotheses

Volumn 54, Issue 4, 2000, Pages 619-623

  Marczynski, B ^a   Peel, M ^b   Baur, X ^a  

^a RUHR UNIVERSITY BOCHUM   (Germany)

^b CARLETON UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT; DEOXYGUANOSINE DERIVATIVE; DNA FRAGMENT; GLUTATHIONE; HEMOGLOBIN; HYDROGEN PEROXIDE; MANDELIC ACID; OXIDIZING AGENT; PHENYLGLYOXYLIC ACID; PLASMA PROTEIN; STYRENE; STYRENE OXIDE;

BIOLOGICAL MONITORING; DNA ADDUCT; DNA DAMAGE; DNA REPAIR; DNA STRAND BREAKAGE; GENOTOXICITY; HUMAN; LEUKOCYTE; LIPID PEROXIDATION; OCCUPATIONAL EXPOSURE; OCCUPATIONAL HEALTH; OXIDATIVE STRESS; PRIORITY JOURNAL; REVIEW; RISK ASSESSMENT;

EID: 0034104686     PISSN: 03069877     EISSN: None     Source Type: Journal    
DOI: 10.1054/mehy.1999.0907     Document Type: Article

References (41)

1. Lorimer W. V., Lilis R., Fischbein A. Health status of styrene-polyester polymerization workers. Scand J Work Environ Health. 4:1978;220-226.
2. Seppäläinen A. M. Neurotoxicity of styrene in occupational and experimental exposure. Scand J Work Environ Health. 4:1978;181-183.
3. Mutti A., Vescovi P. P., Falzoi M., Arfini G., Valenti G., Franchini I. Neuroendocrine effects of styrene in occupationally exposed workers. Scand J Work Envrion Health. 10:1984;225-228.
4. Pfäffli P., Säämänen A. The occupational scene of styrene. Sorsa M., Peltonen K., Vainio H., Hemminki K. Butadiene and Styrene: Assessment of Health Hazards. 1993;15-26 International Agency for Research on Cancer, Lyon.
5. Nakajima T., Elovaara E., Gonzalez F. J., Gelboin H. V., Vainio H., Aoyama T. Characterization of the human cytochrome P450 isozymes responsible for styrene metabolism. Sorsa M., Peltonen K., Vainio H., Hemminki K. Butadiene and Styrene: Assessment of Health Hazards. 1993;101-108 International Agency for Research on Cancer, Lyon.
6. Csanady G. A., Mendrala A. L., Nolan R. J., Filser J. G. A physiologic pharmacokinetic model for styrene and styrene-7,8-oxide in mouse, rat and man. Arch Toxicol. 68:1994;143-157.
7. Korn M., Gfrörer W., Filser J. G., Kessler W. Styrene-7,8-oxide in blood of workers exposed to styrene. Arch Toxicol. 68:1994;524-527.
8. IARC Monographs on the evaluation of carcinogenic risks to humans. Some industrial chemicals. Lyon, International Agency for Research on Cancer, 1994, 60, 233, 346.
9. Sumner S. J., Fennell T. R. Review of the metabolic fate of styrene. Crit Rev Toxicol. 24:1994;S11-S33.
10. Jang J. Y., Droz P. O. Ethnic differences in biological monitoring of several organic solvents II. A simulation study with a physiologically based pharmacokinetic model. Int Arch Occup Environ Health. 70:1997;41-50.
11. Bonassi S., Montanaro F., Ceppi M., Abbondandolo A. Is human exposure to styrene a cause of cytogenetic damage? A re-analysis of the available evidence. Biomarkers. 1:1996;217-225.
12. Phillips D. H., Farmer P. B. Evidence for DNA and protein binding by styrene and styrene oxide. Crit Rev Toxicol. 24:1994;S35-S46.
13. Yeowell-O'Connell K., Pauwels W., Severi M. Comparison of styrene-7,8-oxide adducts formed via reaction with cysteine, N-terminal valine and carboxylic acid residues in human, mouse and rat hemoglobin. Chem Biol Interact. 106:1997;67-85.
14. Savela K., Hesso A., Hemminki K. Characterization of reaction products between styrene oxide and deoxynucleosides and DNA. Chem Biol Interact. 60:1986;235-246.
15. Vodicka P., Hemminki K. Identification of alkylation products of styrene oxide in single- and double-stranded DNA. Carcinogenesis. 9:1988;1657-1660.
16. Bastlova T., Vodicka P., Peterkova K., Hemminki K., Lambert B. Styrene oxide-induced HPRT mutations, DNA adducts and DNA strand breaks in cultured human lymphocytes. Carcinogenesis. 16:1995;2357-2362.
17. 32P-postlabeling. Carcinogenesis. 9:1988;1401-1404.
18. Brenner D. D., Jeffrey A. M., Latriano L. Biomarkers in styrene-exposed boatbuilders. Mutat Res. 61:1991;25-236.
19. Christakopoulos A., Bergmark E., Zorcec V., Norppa H., Mäkki-Paakkanen J., Osterman-Golkar S. Monitoring occupational exposure to styrene from hemoglobin adducts and metabolities in blood. Scand J Work Environ Health. 19:1993;255-263.
20. 32P-postlabeling of DNA adducts of styrene-exposed lamination workers. Carcinogenesis. 14:1993;2059-2061.
21. 32P-postlabelling detection of DNA adducts in mononuclear cells of workers occupationally exposed to styrene. Carcinogenesis. 15:1994;1309-1315.
22. 32P-postlabeling. Carcinogenesis. 15:1994;1949-1953.
23. Walles S. A. S., Orsen I. Single-strand breaks in DNA of various organs of mice induced by styrene and styrene oxide. Cancer Lett. 21:1983;9-15.
24. Walles S. A. S., Edling C., Anundi H., Johanson G. Exposure dependent increase in DNA single strand breaks in leucocytes from workers exposed to low concentrations of styrene. Br J Ind Med. 50:1993;570-574.
25. 6-guanine DNA adducts, DNA strand breaks and mutant frequencies in the hypoxanthine guanine phosphoribosyltransferase gene in T-lymphocytes. Carcinogenesis. 16:1995;1473-1481.
26. Scott D. Cytogenetic studies of workers exposed to styrene: a review. Sorsa M., Peltonen K., Vainio H., Hemminki K. Butadiene and Styrene: Assessment of Health Hazards. 1993;275-286 International Agency for Research on Cancer, Lyon.
27. Scott D., Preston R. J. A critical review of the cytogenetic effects of styrene with an emphasis on human population monitoring - a synopsis. Crit Rev Toxicol. 24:1994;S47-S48.
28. Scott D., Preston R. J. A re-evaluation of the cytogenetic effects of styrene. Mutat Res. 318:1994;175-203.
29. Coggon D. Epidemiological studies of styrene-exposed populations. Crit Rev Toxicol. 24:1994;S107-S115.
30. Kogevinas M., Ferro G., Saracci R. Cancer mortality in an international cohort of workers exposed to styrene. Sorsa M., Peltonen K., Vainio H., Hemminki K. Butadiene and Styrene: Assessment of Health Hazards. 1993;289-300 International Agency for Research on Cancer, Lyon.
31. Marczynski B., Peel M., Baur X. Changes in high molecular weight DNA fragmentation following human blood exposure to styrene-7,8-oxide. Toxicology. 120:1997;111-117.
32. Dawson V. L., Dawson T. M. Free radicals and neuronal cell death. Cell Death Differ. 3:1996;71-78.
33. Chakrabarti S., Duhr M. A., Senecal-Quevillon M., Richer C. L. Dose-dependent genotoxic effects of styrene on human blood lymphocytes and the relationship to its oxidative and metabolic effects. Environ Mol Mutagen. 22:1993;85-92.
34. Katoh T., Higashi K., Inoue N. Sub-chronic effects of styrene and styrene oxide on lipid peroxidation and the metabolism of glutathione in rat liver and brain. J Toxicol Sci. 14:1989;1-9.
35. Marczynski B., Rozynek P., Elliehausen H.-J., Korn M., Baur X. Detection of 8-hydroxydeoxyguanosine, a marker of oxidative DNA damage, in white blood cells of workers occupationally exposed to styrene. Arch Toxicol. 71:1997;496-500.
36. Floyd R. A. The role of 8-hydroxydeoxyguanosine in carcinogenesis. Carcinogenesis. 11:1990;1447-1450.
37. Ames B. A., Gold L. S. Endogenous mutagens and the cause of aging and cancer. Mutat Res. 250:1991;3-106.
38. Takeuchi T., Nakajima M., Ohta Y., Mure K., Takeshita T., Morimoto K. Evaluation of 8-hydroxydeoxyguanosine, a typical oxidative DNA damage, in human leukocytes. Carcinogenesis. 15:1994;1519-1523.
39. Wiseman H., Halliwell B. Damage to DNA by reactive oxygen and nitrogen species: role in inflammatory disease and progression to cancer. Biochem J. 313:1996;17-29.
40. Wei H., Cai Q., Rahn R., Zhang X. Singlet oxygen involvement in ultraviolet (254 nm) radiation-induced formation of 8-hydroxy-deoxyguanosine in DNA. Free Radic Biol Med. 23:1997;148-154.
41. Shi C. Y., Chua S. C., Lee B. L., Ong H. Y., Jeyaratnam J., Ong C. N. Kinetics of styrene urinary metabolites: a study in a low-level occupational exposure setting in Singapore. Int Arch Occup Environ Health. 65:1994;319-323.