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Volumn 43, Issue 9, 2000, Pages 1699-1704

2-Amino-2-oxazolines as subtype selective α2 adrenoceptor agonists

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 ETHYL 6 METHYLCYCLOHEXYLAMINO) 2 OXAZOLINE; ALPHA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; CYCLOHEXYLAMINO OXAZOLINE I; OXAZOLINE DERIVATIVE; UNCLASSIFIED DRUG;

EID: 0034103806     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm9905256     Document Type: Article
Times cited : (19)

References (27)
  • 1
    • 0029134812 scopus 로고
    • α-and β-adrenoceptors: From the gene to the clinic. 1. Molecular biology and adrenoceptor subclassification
    • Hieble, J. P.; Bondinell, W. E.; Ruffolo, R. R., Jr. α-and β-Adrenoceptors: From the Gene to the Clinic. 1. Molecular Biology and Adrenoceptor Subclassification. J. Med. Chem. 1995, 38, 3415-3444.
    • (1995) J. Med. Chem. , vol.38 , pp. 3415-3444
    • Hieble, J.P.1    Bondinell, W.E.2    Ruffolo R.R., Jr.3
  • 2
    • 0029113808 scopus 로고
    • α-and β-adrenoceptors: From the gene to the clinic. 2. Structure-activity relationships and therapeutic applications
    • Ruffolo, R. R., Jr.; Bondinell, W.; Hieble, J. P. α-and β-Adrenoceptors: From the Gene to the Clinic. 2. Structure-Activity Relationships and Therapeutic Applications. J. Med. Chem. 1985, 38, 3681-3716.
    • (1985) J. Med. Chem. , vol.38 , pp. 3681-3716
    • Ruffolo R.R., Jr.1    Bondinell, W.2    Hieble, J.P.3
  • 3
    • 0027531598 scopus 로고
    • Antinociception induced by alpha-2-adrenoceptor agonists with special emphasis on medetomidine studies
    • Pertovaara, A. Antinociception Induced by Alpha-2-Adrenoceptor Agonists with Special Emphasis on Medetomidine Studies. Prog. Neurobiol 1993, 40, 691-709.
    • (1993) Prog. Neurobiol , vol.40 , pp. 691-709
    • Pertovaara, A.1
  • 6
    • 0025310639 scopus 로고
    • Current status and future goals of the pharmacologic reduction of portal hypertension
    • Lebrec, D. Current Status and Future Goals of The Pharmacologic Reduction of Portal Hypertension. Am. J. Surgery 1990, 160, 19-25.
    • (1990) Am. J. Surgery , vol.160 , pp. 19-25
    • Lebrec, D.1
  • 9
    • 0033547241 scopus 로고    scopus 로고
    • Two functionally distinct alpha2-adrenergic receptors regulate sympathetic neurotransmission
    • (c) Hein, L.; Altman, J. D.; Kobilka, B. K. Two Functionally Distinct Alpha2-Adrenergic Receptors Regulate Sympathetic Neurotransmission. Nature 1999, 402 (6758), 181-184.
    • (1999) Nature , vol.402 , Issue.6758 , pp. 181-184
    • Hein, L.1    Altman, J.D.2    Kobilka, B.K.3
  • 10
    • 0028085353 scopus 로고
    • A convenient synthesis of 2-Amino-2-oxazolines and their pharmacological evaluation at cloned human a adrenergic receptors
    • (a) Wong, W. C.; Wang, D.; Forray, C.; Vaysse, P. J.-J.; Branchek, T. A.; Gluchowski, C. A Convenient Synthesis of 2-Amino-2-Oxazolines and Their Pharmacological Evaluation at Cloned Human a Adrenergic Receptors. Bioorg. Med. Chem. Lett. 1994, 4, 2317-2322.
    • (1994) Bioorg. Med. Chem. Lett. , vol.4 , pp. 2317-2322
    • Wong, W.C.1    Wang, D.2    Forray, C.3    Vaysse, P.J.-J.4    Branchek, T.A.5    Gluchowski, C.6
  • 14
    • 0015369115 scopus 로고
    • Zum mechanismus der antihypertensiven wirkung des oxazolin-derivates BAY a6781
    • Jacob, F.; Werner, U.; Schumann, H. J. Zum Mechanismus der Antihypertensiven Wirkung des Oxazolin-Derivates BAY a6781. Arzneim.-Forsch. 1972, 22, 1124-1126.
    • (1972) Arzneim.-Forsch. , vol.22 , pp. 1124-1126
    • Jacob, F.1    Werner, U.2    Schumann, H.J.3
  • 16
    • 0025881062 scopus 로고
    • Three-dimensional models of neurotransmitter G-Binding protein-coupled receptors
    • Hibert, M. F.; Trumpp-Kallmeyer, S.; Bruinvels, A.; Hoflack, J. Three-Dimensional Models of Neurotransmitter G-Binding Protein-Coupled Receptors. Mol. Pharmacol. 1991, 40, 8-15.
    • (1991) Mol. Pharmacol. , vol.40 , pp. 8-15
    • Hibert, M.F.1    Trumpp-Kallmeyer, S.2    Bruinvels, A.3    Hoflack, J.4
  • 17
    • 0021871375 scopus 로고
    • A computational procedure for determining energetically favorable binding sites on biologically important macromolecules
    • Goodford, P. J. A Computational Procedure for Determining Energetically Favorable Binding Sites on Biologically Important Macromolecules. J. Med. Chem. 1985, 28, 849-857.
    • (1985) J. Med. Chem. , vol.28 , pp. 849-857
    • Goodford, P.J.1
  • 18
    • 0025164892 scopus 로고
    • Applications of simulated annealing to peptides
    • Wilson, S. R.; Cui, W. Applications of Simulated Annealing to Peptides. Biopolymers 1990, 29, 225-235.
    • (1990) Biopolymers , vol.29 , pp. 225-235
    • Wilson, S.R.1    Cui, W.2
  • 19
    • 0026006986 scopus 로고
    • 2A-adrenergic receptors: Identification of amino acids involved in ligand binding and receptor activation by agonists
    • 2A-Adrenergic Receptors: Identification of Amino Acids Involved in Ligand Binding and Receptor Activation by Agonists. Mol. Pharmacol. 1991, 40, 168-179.
    • (1991) Mol. Pharmacol. , vol.40 , pp. 168-179
    • Wang, C.-D.1    Buck, M.A.2    Fraser, C.M.3
  • 21
    • 0000359812 scopus 로고
    • Optically active aromatic chromophores. XI. Circular dichroism studies of some 1-substituted 2-phenylcyclohexanes
    • Verbit, L.; Price, H. C. Optically Active Aromatic Chromophores. XI. Circular Dichroism Studies of Some 1-Substituted 2-Phenylcyclohexanes. J. Am. Chem. Soc. 1972, 94, 5143-5152.
    • (1972) J. Am. Chem. Soc. , vol.94 , pp. 5143-5152
    • Verbit, L.1    Price, H.C.2
  • 22
    • 0000793325 scopus 로고
    • Copper-catalyzed reactions of grignard reagents with epoxides and oxetanes
    • Huynh, C.; Derguini-Boumechal, F.; Linstrumelle, G. Copper-Catalyzed Reactions of Grignard Reagents with Epoxides and Oxetanes. Tetrahedron Lett. 1979, 1503-1506.
    • (1979) Tetrahedron Lett. , pp. 1503-1506
    • Huynh, C.1    Derguini-Boumechal, F.2    Linstrumelle, G.3
  • 26
    • 0342998434 scopus 로고
    • The cis- and trans-2-Benzylcyclohexanols: The reduction of 2-Benzylidene- and 2-Benzyl-cyclohexanones
    • (a) Russell, P. B. The cis- and trans-2-Benzylcyclohexanols: The Reduction of 2-Benzylidene- and 2-Benzyl-cyclohexanones. J. Chem. Soc. 1954, 1771-1774.
    • (1954) J. Chem. Soc. , pp. 1771-1774
    • Russell, P.B.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.