A novel synthetic triazolotriazepine derivative JTT-606 inhibits bone resorption by down-regulation of action and production of bone resorptive factors

Journal of Bone and Mineral Research

Volumn 15, Issue 4, 2000, Pages 674-682

  Chikazu, Daichi ^a   Shindo, Masanori ^b   Iwasaka, Toshiki ^b   Katagiri, Mika ^a   Manabe, Noriyo ^a   Takato, Tsuyoshi ^a   Nakamura, Kozo ^a   Kawaguchi, Hiroshi ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b JAPAN TOBACCO INC   (Japan)

Author keywords

Bone; Osteoclast; Osteoporosis; Ovariectomy; Triazolotriazepine

Indexed keywords

CALCIUM; ESTRADIOL; FIBROBLAST GROWTH FACTOR 2; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 1ALPHA; INTERLEUKIN 6; JTT 606; PARATHYROID HORMONE; TRIAZOLOTRIAZEPINE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ARTICLE; BONE MARROW CELL; CALCIUM TRANSPORT; CALVARIA; DOWN REGULATION; DRUG SYNTHESIS; LUMBAR SPINE; OSTEOCLAST; OSTEOLYSIS; OSTEOPENIA; RABBIT;

EID: 0034103759     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/jbmr.2000.15.4.674     Document Type: Article

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