Symphyseal distention in relation to serum relaxin levels and pelvic pain in pregnancy

Acta Obstetricia et Gynecologica Scandinavica

Volumn 79, Issue 4, 2000, Pages 269-275

  Björklund, Kenneth ^a,c   Bergström, Staffan ^b   Nordström, Marie Louise ^a   Ulmsten, Ulf ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

^c UPPSALA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Pain; Pregnancy; Pubic symphysis; Relaxin; Ultrasonography

Indexed keywords

RELAXIN;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; ECHOGRAPHY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GESTATIONAL AGE; HORMONE BLOOD LEVEL; HUMAN; PELVIS PAIN SYNDROME; PREGNANCY; PRIORITY JOURNAL; PUBIS SYMPHYSIS;

ADULT; CASE-CONTROL STUDIES; CROSS-SECTIONAL STUDIES; FEMALE; HUMANS; PELVIC PAIN; PELVIS; PREGNANCY; PREGNANCY COMPLICATIONS; RELAXIN;

EID: 0034103170     PISSN: 00016349     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-0412.2000.079004269.x     Document Type: Article

References (42)

1. Orvieto R, Achiron A, Ben-Rafael Z, Gelernter I, Achiron R. Low-back pain of pregnancy. Acta Obstet Gynecol Scand 1994; 73: 209-14.
2. Östgaard HC, Andersson GBJ, Karlsson K. Prevalence of back pain in pregnancy. Spine 1991; 16: 549-52.
3. Mantle MJ, Greenwood RM, Currey HLF. Backache in pregnancy. Rheumatol Rehabil 1977; 16: 95-101.
4. MacLennan AH, MacLennan SC. Symptom-giving pelvic girdle relaxation of pregnancy, postnatal pelvic joint syndrome and developmental dysplasia of the hip. The Norwegian Association for Women with Pelvic Girdle Relaxation (Landforeningen for Kvinner med Bekkenløsningsplager). Acta Obstet Gynecol Scand 1997; 76: 760-4.
5. Brynhildsen J, Hansson A, Persson A, Hammar M. Follow-up of patients with low back pain during pregnancy. Obstet Gynecol 1998; 91: 182-6.
6. Östgaard HC, Roos-Hansson E, Zetherström G. Regression of back and posterior pelvic pain after pregnancy. Spine 1996; 21: 2777-80.
7. Todd TW. The pubic symphysis of the guinea-pig in relation to pregnancy and parturition. Am J Anat 1923; 31: 345-57.
8. Chihal JH, Espey LL. Utilisation of the relaxed symphysis pubis of guinea pigs for clues to the mechanism of ovulation. Endocrinology 1973; 93: 1441-5.
9. Hall K. An evaluation of the roles of oestrogen, progesterone and relaxin in producing relaxation of the symphysis pubis of the ovariectomized mouse, using the technique of metachromatic staining with toludine blue. J Endocrinol 1956; 13: 384-93.
10. Weinberg A. An x-ray pelvimetric study of relaxin extract in pelvic expansion. Surg Gynecol Obstet 1956; 103: 303-6.
11. Slate WG. Pelvic girdle relaxation. Obst Gyn 1960; 16: 625-7.
12. Farbrot E. The relationship of the effect and pain of pregnancy to the anatomy of the pelvis. Acta Radiol 1952; 38: 403-17.
13. Heyman J, Lundqvist A. The symphysis pubis in pregnancy and parturition. Acta Obstet Gynecol Scand 1932; 12: 191-226.
14. Abramson D, Roberts SM, Wilson PD. Relaxation of the pelvic joints in pregnancy. Surg Gynecol Obstet 1934; 58: 595-613.
15. Roberts RE. Discussion on the physiology and pathology of the pelvic joints in relation to child-bearing. Proc R Soc Med 1934; 27: 1217-25.
16. Young J. Relaxation of the pelvic joints in pregnancy. J Obstet Gynaecol Br Emp 1940; 47: 493-524.
17. Björklund K, Nordström M-L, Bergström S. Sonographic assessment of symphyseal joint distention during pregnancy and post partum with special reference to pelvic pain. Acta Obstet Gynecol Scand 1998; 78; 125-30.
18. Goldsmith LT, Weiss G, Steinetz BG. Relaxin and its role in pregnancy. Endocrinol Metab Clin North Am 1995; 24: 171-86.
19. Skajaa K. Om svangerskapsopbløtning av bekkenets ledd og smerter som følge herav. (Painful relaxation of pelvic joints in pregnancy.) (In Norwegian with English abstract). Norsk Mag Laegevidensk 1929: 90: 713-29.
20. Kogstad O, Biørnstad N. Bekkenløsning. Patogenese, etiologi, definisjon, epidemiologi. (Pelvic girdle relaxation.) (In Norwegian with English abstract.) Tidsskr Nor Laegeforen 1990; 110: 2209-11.
21. Hansen A, Jensen DV, Larsen E, Wilken-Jensen C, Petersen LK. Relaxin is not related to symptom-giving pelvic girdle relaxation in pregnant women. Acta Obstet Gynecol Scand 1996; 75: 245-9.
22. MacLennan AH. The role of the hormone relaxin in human reproduction and pelvic girdle relaxation. Scand J Rheumatol Suppl 1991; 88: 7-15.
23. MacLennan AH, Nicolson R, Green RC, Bath M. Serum relaxin and pelvic pain of pregnancy. Lancet 1986; ii: 243-4.
24. Petersen LK, Hvidman L, Uldbjerg N. Normal serum relaxin in women with disabling pelvic pain during pregnancy. Gynecol Obstet Invest 1994; 38: 21-3.
25. Albert H, Godskesen M, Westergaard JG, Chard T, Gunn L. Circulating levels of relaxin are normal in pregnant women with pelvic pain. Eur J Obstet Gynecol Reprod Biol 1997; 74: 19-22.
26. Kristiansson P, Svärdsudd K, von Schoultz B. Serum relaxin, symphyseal pain and back pain during pregnancy. Am J Obstet Gynecol 1996; 175: 1342-7.
27. Hagen R. Pelvic girdle relaxation from an orthopaedic point of view. Acta Orthop Scand 1974; 45: 550-63.
28. Bahlmann F, Merz E, Macchiella D, Weber G. Sonographische Darstellung des Symphysenspaltes zur Beurteilung eines Symphysenschadens in der Schwangerschaft und post partum. (The sonographical sign of the widening of the symphysis during pregnancy and post partum.) (In German with English abstract.) Z Geburtshilfe Perinatol 1993; 197: 27-30.
29. Scriven MW, Jones DA, McKnight L. The importance of pubic pain following childbirth: a clinical and ultrasonographic study of diastasis of the pubic symphysis. J R Soc Med 1995; 88: 28-30.
30. Björklund K, Bergström S, Lindgren PG, Ulmsten U. Ultrasonographic measurement of the symphysis pubis. A potential method of studying symphyseolysis in pregnancy. Gynecol Obstet Invest 1996; 42: 151-3.
31. Björklund K, Lindgren PG, Bergström S, Ulmsten U. Sonographic assessment of symphyseal joint distention intra partum. Acta Obstet Gynecol Scand 1997; 76: 227-32.
32. Roos-Hansson E, Zetherström G. Tillförlitlighet av provokationstest vid bakre bäckensmärtor under graviditet. (Reliability of provocation test in posterior pelvic pain during pregnancy.) (In Swedish with English abstract.) Sjukgymnasten 1991; 2: 23-4.
33. Walheim GG, Olerud S, Ribbe T. Motion of the pubic symphysis in pelvic instability. Scand J Rehabil Med 1984; 16: 163-9.
34. Lucas C, Bald LN, Martin MC, Jaffe RB, Drolet DW, Mora-Worms M et al. An enzyme-linked immunosorbent assay to study human relaxin in human pregnancy and in pregnant rhesus monkeys. J Endocrinol 1989; 120: 449-57.
35. Conover WJ. Practical nonparametric statistics. 2nd ed. New York: John Wiley & Sons, 1980: 326.
36. Kamieth H, Reinhardt K. Der ungleiche Symphysenstand. Ein wichtiges Symtom der Beckenringlockerung. Fortschr Röntgenstr 1955; 83: 530-46.
37. Petersen LK, Vogel I, Agger AO, Wertergard J, Nils M, Uldbjerg N. Variations in serum relaxin (hRLX-2) concentrations during human pregnancy. Acta Obstet Gynecol Scand 1995; 74: 251-6.
38. Seeger H, Awirner M, Voelter W, Lippert TH. Relaxin and human chorionic gonadotropin concentrations in blood serum during the first trimester of normal and pathological pregnancy. Gynecol Obstet Invest 1988; 25: 209-12.
39. Sheerwood OD. Relaxin in the physiology of reproduction. In: Knobil E, Niell J et al., editors. New York: Raven Press, 1992: 585-673.
40. Calguneri M, Bird HA, Wright V. Changes in joint laxity during pregnancy. Ann Rheum Dis 1982; 41: 126-8.
41. Östgaard HC, Andersson GBJ, Schultz AB, Miller JAA. The influence of biomechanical factors on low back pain during pregnancy. Spine 1993; 18: 61-5.
42. Schauberger CW, Rooney BL, Goldsmith L, Shenton D, Silva PD, Schaper A. Peripheral joint laxity increases in pregnancy but does not correlate with serum relaxin levels. Am J Obstet Gynecol 1996; 174: 667-71.