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Volumn 20, Issue 5, 2000, Pages 1347-1353

Antithrombotic effect of platelet glycoprotein Ib-blocking monoclonal antibody Fab fragments in nonhuman primates

Author keywords

Glycoprotein Ib; Monoclonal antibodies; Platelet adhesion; Platelet aggregation; Thrombosis

Indexed keywords

GLYCOPROTEIN IB; IMMUNOGLOBULIN F(AB) FRAGMENT; MONOCLONAL ANTIBODY; MONOLCONAL ANTIBODY 6 B 4; UNCLASSIFIED DRUG;

EID: 0034101943     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.20.5.1347     Document Type: Article
Times cited : (128)

References (42)
  • 1
    • 0027416021 scopus 로고
    • Thromboregulation: Multicellular modulation of platelet reactivity in hemostasis and thrombosis
    • Marcus AJ, Safier LB. Thromboregulation: multicellular modulation of platelet reactivity in hemostasis and thrombosis. FASEB J. 1993;7: 516-522.
    • (1993) FASEB J , vol.7 , pp. 516-522
    • Marcus, A.J.1    Safier, L.B.2
  • 2
    • 0021847311 scopus 로고
    • Plaque fissuring: The cause of acute myocardial infarction, sudden ischaemic death, and crescendo angina
    • Davies MJ, Thomas AC. Plaque fissuring: the cause of acute myocardial infarction, sudden ischaemic death, and crescendo angina. Br Heart J. 1985;53:363-373.
    • (1985) Br Heart J , vol.53 , pp. 363-373
    • Davies, M.J.1    Thomas, A.C.2
  • 4
    • 0032855948 scopus 로고    scopus 로고
    • Platelet collagen receptors: A new target for inhibition?
    • Clemetson KJ. Platelet collagen receptors: a new target for inhibition? Haemostasis. 1999;29:16-26.
    • (1999) Haemostasis , vol.29 , pp. 16-26
    • Clemetson, K.J.1
  • 6
    • 0017276144 scopus 로고
    • Bernard-Soulier syndrome: A new platelet glycoprotein abnormality: Its relationship with platelet adhesion to subendothelium and with the factor VIII von Willebrand protein
    • Caen JP, Nurden AT, Jeanneau C, Michel H, Tobelem G, Levy-Toledano S, Sultan Y, Valensi F, Bernard J. Bernard-Soulier syndrome: a new platelet glycoprotein abnormality: its relationship with platelet adhesion to subendothelium and with the factor VIII von Willebrand protein. J Lab Clin Med. 1976;87:586-596.
    • (1976) J Lab Clin Med , vol.87 , pp. 586-596
    • Caen, J.P.1    Nurden, A.T.2    Jeanneau, C.3    Michel, H.4    Tobelem, G.5    Levy-Toledano, S.6    Sultan, Y.7    Valensi, F.8    Bernard, J.9
  • 7
    • 0030757166 scopus 로고    scopus 로고
    • Platelet glycoprotein IIb/IIIa integrin blockade: Recent clinical trials in interventional cardiology
    • Tcheng JE. Platelet glycoprotein IIb/IIIa integrin blockade: recent clinical trials in interventional cardiology. Thromb Haemost. 1997;78:205-209.
    • (1997) Thromb Haemost , vol.78 , pp. 205-209
    • Tcheng, J.E.1
  • 8
    • 0031862517 scopus 로고    scopus 로고
    • Blood flow and antithrombotic drug effects
    • Hanson SR, Sakariassen KS. Blood flow and antithrombotic drug effects. Am Heart J. 1998;135:S132-S145.
    • (1998) Am Heart J , vol.135
    • Hanson, S.R.1    Sakariassen, K.S.2
  • 9
    • 0030611288 scopus 로고    scopus 로고
    • GPIIb/IIIa antagonists: Pathophysiologic and therapeutic insights from studies of c7E3 Fab
    • Coller BS. GPIIb/IIIa antagonists: pathophysiologic and therapeutic insights from studies of c7E3 Fab. Thromb Haemost. 1997;78:730-735.
    • (1997) Thromb Haemost , vol.78 , pp. 730-735
    • Coller, B.S.1
  • 10
    • 0028361191 scopus 로고
    • Relative antithrombotic effects of monoclonal antibodies targeting different platelet glycoprotein-adhesive molecule interactions in nonhuman primates
    • Cadroy Y, Hanson SR, Kelly AB, Marzec UM, Evatt BL, Kunicki TJ, Montgomery RR, Harker LA. Relative antithrombotic effects of monoclonal antibodies targeting different platelet glycoprotein-adhesive molecule interactions in nonhuman primates. Blood. 1994;83:3218-3224.
    • (1994) Blood , vol.83 , pp. 3218-3224
    • Cadroy, Y.1    Hanson, S.R.2    Kelly, A.B.3    Marzec, U.M.4    Evatt, B.L.5    Kunicki, T.J.6    Montgomery, R.R.7    Harker, L.A.8
  • 12
    • 0030800626 scopus 로고    scopus 로고
    • Anti-thrombotic effects and bleeding risk of AJvW-2, a monoclonal antibody against human von Willebrand factor
    • Kageyama S, Yamamoto H, Nagano M, Arisaka H, Kayahara T, Yoshimoto R. Anti-thrombotic effects and bleeding risk of AJvW-2, a monoclonal antibody against human von Willebrand factor. Br J Pharmacol. 1997;122:165-171.
    • (1997) Br J Pharmacol , vol.122 , pp. 165-171
    • Kageyama, S.1    Yamamoto, H.2    Nagano, M.3    Arisaka, H.4    Kayahara, T.5    Yoshimoto, R.6
  • 13
    • 0027212250 scopus 로고
    • Echicetin: A snake venom protein that inhibits binding of von Willebrand factor and alboaggregins to platelet glycoprotein Ib
    • Peng M, Lu W, Beviglia L, Niewiarowski S, Kirby EP. Echicetin: a snake venom protein that inhibits binding of von Willebrand factor and alboaggregins to platelet glycoprotein Ib. Blood. 1993;81:2321-2328.
    • (1993) Blood , vol.81 , pp. 2321-2328
    • Peng, M.1    Lu, W.2    Beviglia, L.3    Niewiarowski, S.4    Kirby, E.P.5
  • 14
    • 0032031490 scopus 로고    scopus 로고
    • Antithrombotic effect of crotalin, a platelet membrane glycoprotein Ib antagonist from venom of Crotalus atrox
    • Chang MC, Lin HK, Peng HC, Huang TF. Antithrombotic effect of crotalin, a platelet membrane glycoprotein Ib antagonist from venom of Crotalus atrox. Blood. 1998;91:1582-1589.
    • (1998) Blood , vol.91 , pp. 1582-1589
    • Chang, M.C.1    Lin, H.K.2    Peng, H.C.3    Huang, T.F.4
  • 15
    • 0029123084 scopus 로고
    • Aurintricarboxylic acid reduces platelet deposition in stenosed and endothelially injured rabbit carotid arteries more effectively than other antiplatelet interventions
    • Golino P, Ragni M, Cirillo P, Pascucci I, Ezekowitz MD, Pawashe A, Scognamiglio A, Pace L, Guarino A, Chiariello M. Aurintricarboxylic acid reduces platelet deposition in stenosed and endothelially injured rabbit carotid arteries more effectively than other antiplatelet interventions. Thromb Haemost. 1995;74:974-979.
    • (1995) Thromb Haemost , vol.74 , pp. 974-979
    • Golino, P.1    Ragni, M.2    Cirillo, P.3    Pascucci, I.4    Ezekowitz, M.D.5    Pawashe, A.6    Scognamiglio, A.7    Pace, L.8    Guarino, A.9    Chiariello, M.10
  • 16
    • 0029077090 scopus 로고
    • VCL, an antagonist of the platelet GP1b receptor, markedly inhibits platelet adhesion and intimal thickening after balloon injury in the rat
    • Zahger D, Fishbein MC, Garfinkel LI, Shah PK, Forrester JS, Regnstrom J, Yano J, Cercek B. VCL, an antagonist of the platelet GP1b receptor, markedly inhibits platelet adhesion and intimal thickening after balloon injury in the rat. Circulation. 1995;92:1269-1273.
    • (1995) Circulation , vol.92 , pp. 1269-1273
    • Zahger, D.1    Fishbein, M.C.2    Garfinkel, L.I.3    Shah, P.K.4    Forrester, J.S.5    Regnstrom, J.6    Yano, J.7    Cercek, B.8
  • 17
    • 0028641293 scopus 로고
    • Abolition of cyclic flow variations in stenosed, endothelium-injured coronary arteries in nonhuman primates with a peptide fragment (VCL) derived from human plasma von Willebrand factor-glycoprotein Ib binding domain
    • McGhie AI, McNatt J, Ezov N, Cui K, Mower LK, Hagay Y, Buja LM, Garfinkel LI, Gorecki M, Willerson JT. Abolition of cyclic flow variations in stenosed, endothelium-injured coronary arteries in nonhuman primates with a peptide fragment (VCL) derived from human plasma von Willebrand factor-glycoprotein Ib binding domain. Circulation. 1994;90: 2976-2981.
    • (1994) Circulation , vol.90 , pp. 2976-2981
    • McGhie, A.I.1    McNatt, J.2    Ezov, N.3    Cui, K.4    Mower, L.K.5    Hagay, Y.6    Buja, L.M.7    Garfinkel, L.I.8    Gorecki, M.9    Willerson, J.T.10
  • 18
    • 0028240844 scopus 로고
    • Blockade of platelet membrane glycoprotein Ib receptors delays intracoronary thrombogenesis, enhances thrombolysis, and delays coronary artery reocclusion in dogs
    • Yao SK, Ober JC, Garfinkel LI, Hagay Y, Ezov N, Ferguson JJ, Anderson HV, Panet A, Gorecki M, Buja LM. Blockade of platelet membrane glycoprotein Ib receptors delays intracoronary thrombogenesis, enhances thrombolysis, and delays coronary artery reocclusion in dogs. Circulation. 1994;89:2822-2828.
    • (1994) Circulation , vol.89 , pp. 2822-2828
    • Yao, S.K.1    Ober, J.C.2    Garfinkel, L.I.3    Hagay, Y.4    Ezov, N.5    Ferguson, J.J.6    Anderson, H.V.7    Panet, A.8    Gorecki, M.9    Buja, L.M.10
  • 19
    • 0028825737 scopus 로고
    • Characterization of the unique mechanism mediating the shear-dependent binding of soluble von Willebrand factor to platelets
    • Goto S, Salomon DR, Ikeda Y, Ruggeri ZM. Characterization of the unique mechanism mediating the shear-dependent binding of soluble von Willebrand factor to platelets. J Biol Chem. 1995;270:23352-23361.
    • (1995) J Biol Chem , vol.270 , pp. 23352-23361
    • Goto, S.1    Salomon, D.R.2    Ikeda, Y.3    Ruggeri, Z.M.4
  • 21
    • 0027173382 scopus 로고
    • Artificial microvascular graft thrombosis: The consequences of platelet membrane glycoprotein Ib inhibition and thrombin inhibition
    • Dascombe WH, Hong C, Garrett KO, White JG, Lyle VA, Miller JL, Johnson PC. Artificial microvascular graft thrombosis: the consequences of platelet membrane glycoprotein Ib inhibition and thrombin inhibition. Blood. 1993;82:126-134.
    • (1993) Blood , vol.82 , pp. 126-134
    • Dascombe, W.H.1    Hong, C.2    Garrett, K.O.3    White, J.G.4    Lyle, V.A.5    Miller, J.L.6    Johnson, P.C.7
  • 22
    • 0024392126 scopus 로고
    • Effects of an antiplatelet glycoprotein Ib antibody on hemostatic function in the guinea pig
    • Becker BH, Miller JL. Effects of an antiplatelet glycoprotein Ib antibody on hemostatic function in the guinea pig. Blood. 1989;74:690-694.
    • (1989) Blood , vol.74 , pp. 690-694
    • Becker, B.H.1    Miller, J.L.2
  • 23
    • 0010732089 scopus 로고    scopus 로고
    • Differential effects of monoclonal antibodies to rat GPIIb-IIIa, GPIba or GPV on platelet function and in vivo survival
    • Abstract
    • Ravanat C, Freund M, Moog S, Mangin P, Azorsa D, Schwartz C, Lanza F, Cazenave J. Differential effects of monoclonal antibodies to rat GPIIb-IIIa, GPIba or GPV on platelet function and in vivo survival. Thromb Haemost. 1999;82(suppl):528a. Abstract.
    • (1999) Thromb Haemost , vol.82 , Issue.SUPPL.
    • Ravanat, C.1    Freund, M.2    Moog, S.3    Mangin, P.4    Azorsa, D.5    Schwartz, C.6    Lanza, F.7    Cazenave, J.8
  • 24
    • 0023124182 scopus 로고
    • The glycoprotein Ib complex of human blood platelets
    • Wicki AN, Clemetson KJ. The glycoprotein Ib complex of human blood platelets. Eur J Biochem. 1987;163:43-50.
    • (1987) Eur J Biochem , vol.163 , pp. 43-50
    • Wicki, A.N.1    Clemetson, K.J.2
  • 25
    • 0016756272 scopus 로고
    • Continuous cultures of fused cells secreting antibody of predefined specificity
    • Kohler G, Milstein C. Continuous cultures of fused cells secreting antibody of predefined specificity. Nature. 1975;256:495-497.
    • (1975) Nature , vol.256 , pp. 495-497
    • Kohler, G.1    Milstein, C.2
  • 26
    • 0027267973 scopus 로고
    • Expression and characterization of functionally active fragments of the platelet glycoprotein (GP) Ib-IX complex in mammalian cells: Incorporation of GP Ibα into the cell surface membrane
    • Meyer S, Kresbach G, Raring P, Schumpp Vonach B, Clemetson KJ, Hadvary P, Steiner B. Expression and characterization of functionally active fragments of the platelet glycoprotein (GP) Ib-IX complex in mammalian cells: incorporation of GP Ibα into the cell surface membrane. J Biol Chem. 1993;268:20555-20562.
    • (1993) J Biol Chem , vol.268 , pp. 20555-20562
    • Meyer, S.1    Kresbach, G.2    Raring, P.3    Schumpp Vonach, B.4    Clemetson, K.J.5    Hadvary, P.6    Steiner, B.7
  • 28
    • 0025727990 scopus 로고
    • Isolation and chemical characterization of two structurally and functionally distinct forms of botrocetin, the platelet coagglutinin isolated from the venom of Bothrops jararaca
    • Fujimura Y, Titani K, Usami Y, Suzuki M, Oyama R, Matsui T, Fukui H, Sugimoto M, Ruggeri ZM. Isolation and chemical characterization of two structurally and functionally distinct forms of botrocetin, the platelet coagglutinin isolated from the venom of Bothrops jararaca. Biochemistry. 1991;30:1957-1964.
    • (1991) Biochemistry , vol.30 , pp. 1957-1964
    • Fujimura, Y.1    Titani, K.2    Usami, Y.3    Suzuki, M.4    Oyama, R.5    Matsui, T.6    Fukui, H.7    Sugimoto, M.8    Ruggeri, Z.M.9
  • 29
    • 0028928893 scopus 로고
    • Calin from Hirudo medicinalis, an inhibitor of von Willebrand factor binding to collagen under static and flow conditions
    • Harsfalvi J, Stassen JM, Hoylaerts MF, Van Houtte E, Sawyer RT, Vermylen J, Deckmyn H. Calin from Hirudo medicinalis, an inhibitor of von Willebrand factor binding to collagen under static and flow conditions. Blood. 1995;85:705-711.
    • (1995) Blood , vol.85 , pp. 705-711
    • Harsfalvi, J.1    Stassen, J.M.2    Hoylaerts, M.F.3    Van Houtte, E.4    Sawyer, R.T.5    Vermylen, J.6    Deckmyn, H.7
  • 30
    • 0022401020 scopus 로고
    • Platelet interactions with Dacron vascular grafts: A model of acute thrombosis in baboons
    • Hanson SR, Kotze HF, Savage B, Harker LA. Platelet interactions with Dacron vascular grafts: a model of acute thrombosis in baboons. Arteriosclerosis. 1985;5:595-603.
    • (1985) Arteriosclerosis , vol.5 , pp. 595-603
    • Hanson, S.R.1    Kotze, H.F.2    Savage, B.3    Harker, L.A.4
  • 34
    • 0017874586 scopus 로고
    • Proteins and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3a,6a-diphenylglycoluril
    • Fraker PJ, Speck JC. Proteins and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3a,6a-diphenylglycoluril. Biochem Biophys Res Commun. 1978;80:849-857.
    • (1978) Biochem Biophys Res Commun , vol.80 , pp. 849-857
    • Fraker, P.J.1    Speck, J.C.2
  • 35
    • 0025274917 scopus 로고
    • Low molecular weight heparin as an anticoagulant for in vitro platelet function studies
    • van Wyk V, Heyns AD. Low molecular weight heparin as an anticoagulant for in vitro platelet function studies. Thromb Res. 1990;57: 601-609.
    • (1990) Thromb Res , vol.57 , pp. 601-609
    • Van Wyk, V.1    Heyns, A.D.2
  • 36
    • 0028245488 scopus 로고
    • Glycoprotein Ib and von Willebrand factor in the process of thrombus formation
    • Ruggeri ZM. Glycoprotein Ib and von Willebrand factor in the process of thrombus formation. Ann N Y Acad Sci. 1994;714:200-210.
    • (1994) Ann N Y Acad Sci , vol.714 , pp. 200-210
    • Ruggeri, Z.M.1
  • 37
    • 0029030141 scopus 로고
    • Bleeding complications with the chimeric antibody to platelet glycoprotein IIb/IIIa integrin in patients undergoing percutaneous coronary intervention: EPIC Investigators
    • Aguirre FV, Topol EJ, Ferguson JJ, Anderson K, Blankenship JC, Heuser RR, Sigmon K, Taylor M, Gottlieb R, Hanovich G. Bleeding complications with the chimeric antibody to platelet glycoprotein IIb/IIIa integrin in patients undergoing percutaneous coronary intervention: EPIC Investigators. Circulation. 1995;91:2882-2890.
    • (1995) Circulation , vol.91 , pp. 2882-2890
    • Aguirre, F.V.1    Topol, E.J.2    Ferguson, J.J.3    Anderson, K.4    Blankenship, J.C.5    Heuser, R.R.6    Sigmon, K.7    Taylor, M.8    Gottlieb, R.9    Hanovich, G.10
  • 38
    • 0025724038 scopus 로고
    • von Willebrand factor binding to platelet GPIβ initiates signals for platelet activation
    • Kroll MH, Harris TS, Moake JL, Handin RI, Schafer AI. von Willebrand factor binding to platelet GPIβ initiates signals for platelet activation. J Clin Invest. 1991;88:1568-1573.
    • (1991) J Clin Invest , vol.88 , pp. 1568-1573
    • Kroll, M.H.1    Harris, T.S.2    Moake, J.L.3    Handin, R.I.4    Schafer, A.I.5
  • 39
    • 0031454108 scopus 로고    scopus 로고
    • Glycoprotein Ib-von Willebrand factor interactions activate tyrosine kinases in human platelets
    • Asazuma N, Ozaki Y, Satoh K, Yatomi Y, Handa M, Fujimura Y, Miura S, Kume S. Glycoprotein Ib-von Willebrand factor interactions activate tyrosine kinases in human platelets. Blood. 1997;90:4789-4798.
    • (1997) Blood , vol.90 , pp. 4789-4798
    • Asazuma, N.1    Ozaki, Y.2    Satoh, K.3    Yatomi, Y.4    Handa, M.5    Fujimura, Y.6    Miura, S.7    Kume, S.8
  • 40
    • 0021139987 scopus 로고
    • Cellular transformation by coordinate action of three peptide growth factors from human platelets
    • Assoian RK, Grotendorst GR, Miller DM, Sporn MB. Cellular transformation by coordinate action of three peptide growth factors from human platelets. Nature. 1984;309:804-806.
    • (1984) Nature , vol.309 , pp. 804-806
    • Assoian, R.K.1    Grotendorst, G.R.2    Miller, D.M.3    Sporn, M.B.4
  • 42
    • 0033168347 scopus 로고    scopus 로고
    • Contribution of distinct adhesive interactions to platelet aggregation in flowing blood
    • Ruggeri ZM, Dent JA, Saldivar E. Contribution of distinct adhesive interactions to platelet aggregation in flowing blood. Blood. 1999;94: 172-178.
    • (1999) Blood , vol.94 , pp. 172-178
    • Ruggeri, Z.M.1    Dent, J.A.2    Saldivar, E.3


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