Mutants of p53 gene presence in laryngeal carcinoma and adjacent histopathologically normal tissue

ORL

Volumn 62, Issue 3, 2000, Pages 140-142

  Jin, Xiaojie ^a   Zhou, Liang ^a   Zhao, Aiguang ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Gene mutation; Histopathology; Laryngeal cancer; p53

Indexed keywords

PROTEIN P53;

ADULT; AGED; ARTICLE; CANCER GENETICS; CARCINOGENESIS; CLINICAL ARTICLE; FEMALE; GENE MUTATION; HISTOPATHOLOGY; HUMAN; LARYNX CARCINOMA; MALE; MOLECULAR BIOLOGY; PRIORITY JOURNAL;

EID: 0034100909     PISSN: 03011569     EISSN: None     Source Type: Journal    
DOI: 10.1159/000027734     Document Type: Article

References (7)

1. Shin DM, Ro JY, Hong WK, Hittelman WN: Dysregulation of epidermal growth factor receptor expression in premalignant lesions during head and neck tumorigenesis. Cancer Res 1994;54:3153-3159.
2. Knudson AG: Hereditary cancer, oncogenes and antioncogenes. Cancer Res 1985;45:1437-1443.
3. Nigro JM, Baker SJ, Pressinger AC, Jessup JM, Hosteller R, Cleary K, Bigner SH, Davidson N, Bayin S, Devileem P, Glover T, Collins FS, Weston A, Modali R, Harris CC, Vogelstein B: Mutations in the p53 gene occur in diverse human tumor types. Natur (Lond) 1989;342: 705-708.
4. Bachman DG, Graves D, Yokes E, Beckett M, Haraf D, Montag A, Dunphy E, Mick R, Yandell D, Weichselbaum RR: Occurrence of p53 gene deletion and human papilloma virus infection in head and neck cancer. Cancer Res 1992;52:4832-4836.
5. Gusterson BA, Anbazhagan R, Warren W, Midgely C, Lane DP, O'Hare M, Stamps A, Carter R, Jayatilake H: Expression of p53 in premalignant and malignant squamous epithelium. Oncogene 1991;6:1785-1789.
6. Carles D, Traissac L, Herfaut G: The local approaches of the extension of laryngeal cancers: Implication of the anatomopathological examination of laryngectomy operative parts. Rev Laryngol 1991;112:193-198.
7. Shin DM, Kim J, Ro JY, Hittelman J, Roth JA, Hong WK, Hittelman WN: Activation of p53 gene expression in premalignant lesions during head and neck tumourigenesis. Cancer Res 1994;54:321-326.