Mutant presenilin 1 increases the levels of Alzheimer amyloid β-peptide aβ42 in late compartments of the constitutive secretory pathway

Journal of Neurochemistry

Volumn 74, Issue 5, 2000, Pages 1878-1884

  Petanceska, Suzana S ^a,b   Seeger, Mary ^b   Checler, Frederic ^c   Gandy, Sam ^a,b  

^a NEW YORK UNIVERSITY   (United States)

^b ROCKEFELLER UNIVERSITY   (United States)

^c INSTITUT DE PHARMACOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

Author keywords

Amyloid peptide; Familial Alzheimer's disease; Neuroblastoma; Plasma membrane; Proteolytic processing; Rab; Trans Golgi network

Indexed keywords

AMYLOID BETA PROTEIN; NOTCH RECEPTOR; PRESENILIN 1;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; GENE ACTIVITY; GENE CONTROL; GENE LOCATION; GENE MUTATION; GOLGI COMPLEX; MEMBRANE VESICLE; MOUSE; NEUROBLASTOMA CELL; NONHUMAN; PRIORITY JOURNAL;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; ANIMALS; HUMANS; MEMBRANE PROTEINS; MICE; MUTATION; PEPTIDE FRAGMENTS; PRESENILIN-1; SUBCELLULAR FRACTIONS; TISSUE DISTRIBUTION; TUMOR CELLS, CULTURED;

ANIMALIA;

EID: 0034100349     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2000.0741878.x     Document Type: Article

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