Comparison of cyanamide and disulfiram in effects on liver function

Alcoholism: Clinical and Experimental Research

Volumn 24, Issue 4 SUPPL., 2000, Pages

  Tamai, Hironao ^a   Yokoyama, Akira ^a   Okuyama, Keiji ^a   Takahashi, Hisao ^a   Maruyama, Katsuya ^a   Suzuki, Yukako ^a   Ishii, Hiromasa ^b  

^a KURIHAMA NATIONAL HOSPITAL   (Japan)

^b KEIO UNIVERSITY   (Japan)

Author keywords

Alcoholic Liver Disease; Alcoholism; Cyanamide; Disulfiram

Indexed keywords

ALANINE AMINOTRANSFERASE; ALCOHOL; ASPARTATE AMINOTRANSFERASE; CYANAMIDE; DISULFIRAM;

ADULT; ALCOHOLISM; CONFERENCE PAPER; DETOXIFICATION; DISEASE ASSOCIATION; DOSE LIVER FUNCTION RELATION; DRUG ABSORPTION; DRUG MECHANISM; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; INCIDENCE; LIVER FUNCTION; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL;

EID: 0034098676     PISSN: 01456008     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1530-0277.2000.tb00021.x     Document Type: Conference Paper

References (13)

1. American Psychiatric Association (1987) Diagnostic and Statistical Manual of Mental Disorders, 3rd ed rev. American Psychiatric Association, Washington DC.
2. Berlin RG (1989) Disulfiram hepatotoxicity: A consideration of its mechanism and clinical spectrum. Alcohol Alcohol 24:241-246.
3. Bruguera M, Lamar C, Bernet M, Rodés J (1986) Hepatic disease associated with ground-glass inclusions in hepatocytes after cyanamide therapy. Arch Pathol Lab Med 110:906-910.
4. Fuller RK, Branchey L, Brightwell DR (1986) Disulfiram treatment of alcoholism: A Veterans Administration cooperative study. JAMA 256: 1449-1455.
5. Guillen FJ, Vazquez JJ (1984) Cyanamide-induced liver cell injury. Experimental study in the rat. Lab Invest 50:385-393.
6. Moreno A, Vazquez JJ, Ruiz del Arbol L, Guillen FJ, Colina F (1984) Structural hepatic changes associated with cyanamide treatment: Cholangiolar proliferation, fibrosis and cirrhosis. Liver 4:15-21.
7. Peachey JE, Annis HM, Bornstein ER, Sykora K, Maglana SM, Shamai S (1989) Carcium carbimide in alcoholism treatment: 1. A placebo-controlled, double-blind clinical trial of short-term efficacy. Br J Addict 84:877-887.
8. Swift RM (1999) Drug therapy for alcohol dependence. N Engl J Med 340:1482-1490.
9. Suzuki Y, Yokoyama A, Nakano M, Okuyama K, Takahashi H, Tamai H, Maruyama K, Ishii H (2000) Cyanamide-induced liver dysfunction after abstinence in alcoholics: A long-term follow-up study on four cases. Alcohol Clin Exp Res (Suppl.) 24:100S-105S.
10. Vázquez JJ, Cervera S (1980) Cyanamide-induced liver injury in alcoholics. Lancet 1:361-362.
11. Vázquez JJ, Diaz de Otazu R, Guillen FJ, Zozaya J, Pardo FJ (1983) Hepatitis induced by drugs used as alcohol aversion therapy. Diagn Histopathol 6:29-37.
12. Wright C, Moore RD, Grodin DM, Spyker DA, Gill EV (1993) Screening for disulfiram-induced liver test dysfunction in an inpatient alcoholism program. Alcohol Clin Exp Res 17:187-191.
13. Yokoyama A, Sato S, Maruyama K, Nakano M, Takahashi H, Okuyama K, Takagi S, Takagi T, Yokoyama T, Hayashida M, Ishii H (1995) Cyanamide-associated alcoholic liver disease: A sequential histological evaluation. Alcohol Clin Exp Res 19:1307-1311.