A study of tea tree oil ototoxicity

Audiology and Neuro-Otology

Volumn 5, Issue 2, 2000, Pages 64-68

  Zhang, Si Yi ^a,b   Robertson, Donald ^a  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^b GUANGDONG PROVINCIAL PEOPLE'S HOSPITAL   (China)

Author keywords

Compound action potential; External and middle ear infection; Ototoxicity; Tea tree oil

Indexed keywords

TEA TREE OIL;

ACTION POTENTIAL; ANIMAL EXPERIMENT; ARTICLE; COCHLEA; COCHLEA FENESTRA; COCHLEAR NERVE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG SAFETY; EXTERNAL OTITIS; GUINEA PIG; NONHUMAN; OTITIS MEDIA; OTOTOXICITY; PRIORITY JOURNAL;

EID: 0034097803     PISSN: 14203030     EISSN: None     Source Type: Journal    
DOI: 10.1159/000013869     Document Type: Article

References (20)

1. Aguis AM, Pickles JM, Burch KL: A prospective study of otitis externa. Clin Otolaryngol 1992; 17:150-154.
2. Altman PM: Australian tea tree oil. Austral J Pharmacy 1988;69:276-278.
3. Basset IB, Pannowitz DL, Barnetson RSC: A comparative study of tea tree oil versus benzoyl peroxide in the treatment of acne. Med J Austral 1990;153:455-458.
4. Blackwell AL: Tea tree oil and anaerobic (bacterial) vaginosis. Australas J Dermatol 1992;33:145-149.
5. Brook I: Bacterial flora of stethoscopes' earpieces and otitis externa. Ann Otol Rhinol Laryngol 1997;106:751-752.
6. Carson CF, Hammer KA, Riley TV: Broth microdilution method for determining the susceptibility of Escherichia coli and Staphylococcus aureus to be essential oil of Melaleuca alternifolia (tea tree oil). Microbios 1995;82:181-185.
7. Carson CF, Riley TV: Antimicrobial activity of the essential oil of Melaleuca alternifolia - A review. Lett Appl Microbiol 1993;16:49-55.
8. Carson CF, Riley TV: Susceptibility of Propionibacterium acnes to the essential oil of Melaleuca alternifolia. Lett Appl Microbiol 1994;19: 24-25.
9. Carson CF, Riley TV: Antimicrobial activity of the major components of the essential oil of Melaleuca alternifolia. J Appl Bacteriol 1995;78: 264-269.
10. Clark WB, Brook I, Thompson DH: Microbiology of otitis externa. Otolaryngol Head Neck Surg 1997;116:23-25.
11. Hammer KA, Carson CF, Filey TV: In vitro susceptibility of Malassezia furfur to the essential oil of Melaleuca alternifolia. J Med Vet Mycol 1997;35:375-377.
12. International Standard: Oil of Melaleuca, terpinen-4-ol type (Tea Tree oil). Geneva, International Organisation for Standardisation, 1996.
13. Johnstone JR, Alder VA, Johnstone BM, Robertson D, Yates GK: Cochlcar action potential threshold and single unit thresholds. J Acoust Soc Am 1979;65:254-257.
14. Matsumoto Y, Suzuki Y, Ishii Y, Ishihara R, Nakazawa A, Nakane Y, Nishinari C, Deguchi K: Antimicrobial activity of ofloxacin against recent clinical isolates from otitis media and otitis externa. Jpn J Antibiot 1998;51:561-575.
15. Oshima A, Iizuka T, Ninomiya J, Hamaguchi T, Takiuchi T: Two cases of dermatophytosis of the external auditory meatus. Nippon Ishinkin Gakkai Zasshi 1998;39:99-102.
16. Patuzzi R, Robertson D: Tuning in the mammalian cochlea. Physiol Rev 1988;68:1009-1082.
17. Syed TA, Qureshi ZA, Ali SM, Ahmad S, Ahmad SA: Treatment of toenail onychomycosis with 2% butenafine and 5% Melaleuca alternifolia (tea tree) oil in cream. Med J Aust 1990;153: 455-458.
18. Shanson DC: Microbiology in Clinical Practice, ed 2. London, Wright Butterworth & Co, 1989, p 382.
19. Tong MM, Altman PM, Barnetson RS: Tea tree oil in the treatment of tinea pedis. Trop Med Int Health 1999;4:284-287.
20. Walsh LJ, Longstaff J: The antimicrobial effect of an essential oil on selected oral pathogens. Periodontology 1987;8:11-15.