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Volumn 28, Issue 5, 2000, Pages 503-513

Metabolism, disposition, excretion, and pharmacokinetics of levormeloxifene, a selective estrogen receptor modulator, in the rat

Author keywords

[No Author keywords available]

Indexed keywords

CENTCHROMAN; ESTROGEN DERIVATIVE; ESTROGEN RECEPTOR;

EID: 0034095017     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (16)

References (16)
  • 1
    • 0001486764 scopus 로고    scopus 로고
    • Levormeloxifene, a non-steroidal estrogen receptor therapeutic, prevents bone loss, reduces serum cholesterol and has differentiated uterine effects in the ovariectomised rat
    • Bain S, Shalmi M and Korsgaard N (1997) Levormeloxifene, a non-steroidal estrogen receptor therapeutic, prevents bone loss, reduces serum cholesterol and has differentiated uterine effects in the ovariectomised rat. Maturitas 27:144.
    • (1997) Maturitas , vol.27 , pp. 144
    • Bain, S.1    Shalmi, M.2    Korsgaard, N.3
  • 4
    • 0031458251 scopus 로고    scopus 로고
    • A partial estrogen receptor agonist with strong antiatherogenic properties without noticeable effect on reproductive tissue in cholesterol-fed female and male rabbits
    • Holm P, Shalmi M, Korsgaard N, Guldhammer B, Skouby SO and Stender S (1997) A partial estrogen receptor agonist with strong antiatherogenic properties without noticeable effect on reproductive tissue in cholesterol-fed female and male rabbits. Arterioscler Thromb Vasc Biol 17:2264-2272.
    • (1997) Arterioscler Thromb Vasc Biol , vol.17 , pp. 2264-2272
    • Holm, P.1    Shalmi, M.2    Korsgaard, N.3    Guldhammer, B.4    Skouby, S.O.5    Stender, S.6
  • 5
    • 0006353876 scopus 로고    scopus 로고
    • Levormeloxifene, a non-steroidal estrogen receptor therapeutic, exerts a non-proliferative action on uterine tissues of the ovariectomised rat
    • Korsgaard N, Greenspan DL, Kurman R and Bain S (1997) Levormeloxifene, a non-steroidal estrogen receptor therapeutic, exerts a non-proliferative action on uterine tissues of the ovariectomised rat. Maturitas 27:144.
    • (1997) Maturitas , vol.27 , pp. 144
    • Korsgaard, N.1    Greenspan, D.L.2    Kurman, R.3    Bain, S.4
  • 6
    • 0031039888 scopus 로고    scopus 로고
    • Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors alpha and beta
    • Kuiper GG, Carlsson B. Grandien K, Enmark E, Haggblad J, Nilsson S and Gustafsson JA (1997) Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors alpha and beta. Endocrinology 138:863-870.
    • (1997) Endocrinology , vol.138 , pp. 863-870
    • Kuiper, G.G.1    Carlsson, B.2    Grandien, K.3    Enmark, E.4    Haggblad, J.5    Nilsson, S.6    Gustafsson, J.A.7
  • 9
    • 0021674554 scopus 로고
    • Disposition and metabolism of a new benzothiophene antiestrogen in rats, dogs, and monkeys
    • Lindstrom TD, Whitaker NG and Whitaker GW (1984) Disposition and metabolism of a new benzothiophene antiestrogen in rats, dogs, and monkeys. Xenobiotica 11:841-847.
    • (1984) Xenobiotica , vol.11 , pp. 841-847
    • Lindstrom, T.D.1    Whitaker, N.G.2    Whitaker, G.W.3
  • 10
    • 0034002828 scopus 로고    scopus 로고
    • Metabolism of levormeloxifene, a selective estrogen receptor modulator, in the sprague dawley rat, cynomolgus monkey, and postmenopausal women
    • Mountfield RJ, Panduro AM, Wassmann O, Thompson M, John B and Van Der Merbel N (2000) Metabolism of levormeloxifene, a selective estrogen receptor modulator, in the Sprague Dawley rat, Cynomolgus monkey, and postmenopausal women. Xenobiotica 30:201-217.
    • (2000) Xenobiotica , vol.30 , pp. 201-217
    • Mountfield, R.J.1    Panduro, A.M.2    Wassmann, O.3    Thompson, M.4    John, B.5    Van Der Merbel, N.6
  • 11
    • 0031948975 scopus 로고    scopus 로고
    • Sex dependent metabolism of xenobiotics
    • Mugford CA and Kedderis GL (1998) Sex dependent metabolism of xenobiotics. Drug Metab Rev 30:441-498.
    • (1998) Drug Metab Rev , vol.30 , pp. 441-498
    • Mugford, C.A.1    Kedderis, G.L.2
  • 12
    • 0031939442 scopus 로고    scopus 로고
    • Metabolism of droloxifene in the CD-1 mouse, fischer-344 rat and cynomolgus monkey
    • O'Donnell JP, Khosla NB and Dalvie DK (1998) Metabolism of droloxifene in the CD-1 mouse, Fischer-344 rat and cynomolgus monkey. Xenobiotica 28:153-166.
    • (1998) Xenobiotica , vol.28 , pp. 153-166
    • O'Donnell, J.P.1    Khosla, N.B.2    Dalvie, D.K.3
  • 13
    • 0026322724 scopus 로고
    • The permanent bile fistula rat model
    • Siegers C and Watkins JB eds Gustav Fischer Verlag Press, New York
    • Remie R, Rensema JW, Havinga R and Kuipers F (1991) The permanent bile fistula rat model. in Progress in Pharmacology and Clinical Pharmacology (Siegers C and Watkins JB eds) vol. 8(4), pp. 127-145, Gustav Fischer Verlag Press, New York.
    • (1991) Progress in Pharmacology and Clinical Pharmacology , vol.8 , Issue.4 , pp. 127-145
    • Remie, R.1    Rensema, J.W.2    Havinga, R.3    Kuipers, F.4
  • 15
    • 0005818010 scopus 로고
    • Whole-body autoradiography
    • Bridges JW and Chasseau LF eds John Wiley, New York
    • Ullberg S and Larrson B (1981) Whole-body autoradiography, in Progress in Drug Metabolism (Bridges JW and Chasseau LF eds) pp 249-288, John Wiley, New York.
    • (1981) Progress in Drug Metabolism , pp. 249-288
    • Ullberg, S.1    Larrson, B.2
  • 16
    • 0030917577 scopus 로고    scopus 로고
    • Controversies surrounding estrogen use in postmenopausal women
    • Witt DM and Lousberg TR (1997) Controversies surrounding estrogen use in postmenopausal women. Ann Pharmacother 31:745-755.
    • (1997) Ann Pharmacother , vol.31 , pp. 745-755
    • Witt, D.M.1    Lousberg, T.R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.