메뉴 건너뛰기




Volumn 27, Issue 3, 2000, Pages 172-178

T-0162, a novel free radical scavenger, reduces myocardial infarct size in rabbits

Author keywords

Free radical scavenger; Myocardial infarction; Rabbits; Reperfusion injury; T 0162

Indexed keywords

1 (3 TERT BUTYL 2 HYDROXY 5 METHOXYPHENYL) 3 (3 PYRIDYLMETHYL)UREA; FREE RADICAL; HYDROXYL RADICAL; SCAVENGER; SUPEROXIDE; UNCLASSIFIED DRUG; UREA DERIVATIVE;

EID: 0034093511     PISSN: 03051870     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1440-1681.2000.03222.x     Document Type: Article
Times cited : (4)

References (41)
  • 2
    • 0021343227 scopus 로고
    • Canine myocardial reperfusion injury: Its reduction by the combined administration of superoxide dismutase and catalase
    • 2. Jolly SR, Kane WJ, Baillie MB, Abrams GD, Lucchesi BR. Canine myocardial reperfusion injury: Its reduction by the combined administration of superoxide dismutase and catalase. Circ. Res. 1984; 54: 277-85.
    • (1984) Circ. Res. , vol.54 , pp. 277-285
    • Jolly, S.R.1    Kane, W.J.2    Baillie, M.B.3    Abrams, G.D.4    Lucchesi, B.R.5
  • 3
    • 0015882341 scopus 로고
    • The mitochondrial generation of hydrogen peroxide: General properties and effect of hyperbaric oxygen
    • 3. Boveris A, Chance B. The mitochondrial generation of hydrogen peroxide: General properties and effect of hyperbaric oxygen. Biochem. J. 1973; 134: 707-16.
    • (1973) Biochem. J. , vol.134 , pp. 707-716
    • Boveris, A.1    Chance, B.2
  • 5
    • 0027368720 scopus 로고
    • Ischaemic preconditioning is not mediated by oxygen derived free radicals in rats
    • 5. Richard V, Tron C, Thuillez C. Ischaemic preconditioning is not mediated by oxygen derived free radicals in rats. Cardiovasc. Res. 1993; 27: 2016-21.
    • (1993) Cardiovasc. Res. , vol.27 , pp. 2016-2021
    • Richard, V.1    Tron, C.2    Thuillez, C.3
  • 6
    • 0027944654 scopus 로고
    • Contraction band necrosis: Its modification by the free radical scavenger N-2-mercaptopropionyl glycine
    • 6. Widman SC, Liang CS, Schenk EA, Hood Jr WB. Contraction band necrosis: Its modification by the free radical scavenger N-2-mercaptopropionyl glycine. J. Cardiovasc. Pharmacol. 1994; 24: 694-701.
    • (1994) J. Cardiovasc. Pharmacol. , vol.24 , pp. 694-701
    • Widman, S.C.1    Liang, C.S.2    Schenk, E.A.3    Hood W.B., Jr.4
  • 7
    • 0022982366 scopus 로고
    • Reduction in experimental infarct size by recombinant human superoxide dismutase: Insights into the pathophysiology of reperfusion injury
    • 7. Ambrosio G, Becker LC, Hutchins GM, Weisman HF, Weisfeldt ML. Reduction in experimental infarct size by recombinant human superoxide dismutase: Insights into the pathophysiology of reperfusion injury. Circulation 1986; 74: 1424-33.
    • (1986) Circulation , vol.74 , pp. 1424-1433
    • Ambrosio, G.1    Becker, L.C.2    Hutchins, G.M.3    Weisman, H.F.4    Weisfeldt, M.L.5
  • 8
    • 0025865007 scopus 로고
    • Reduction of canine myocardial infarct size by a diffusible reactive oxygen metabolite scavenger: Efficacy of dimethylthiourea given at the onset of reperfusion
    • 8. Carrea FP, Lesnefsky EJ, Repine JE, Shikes RH, Horwitz LD. Reduction of canine myocardial infarct size by a diffusible reactive oxygen metabolite scavenger: Efficacy of dimethylthiourea given at the onset of reperfusion. Circ. Res. 1991; 68: 1652-9.
    • (1991) Circ. Res. , vol.68 , pp. 1652-1659
    • Carrea, F.P.1    Lesnefsky, E.J.2    Repine, J.E.3    Shikes, R.H.4    Horwitz, L.D.5
  • 9
    • 0026034564 scopus 로고
    • Myocardial infarct size-limiting effect of ischemic preconditioning was not attenuated by oxygen free-radical scavengers in the rabbit
    • 9. Iwamoto T, Miura T, Adachi T et al. Myocardial infarct size-limiting effect of ischemic preconditioning was not attenuated by oxygen free-radical scavengers in the rabbit. Circulation 1991; 83: 1015-22.
    • (1991) Circulation , vol.83 , pp. 1015-1022
    • Iwamoto, T.1    Miura, T.2    Adachi, T.3
  • 10
    • 0025977376 scopus 로고
    • Superoxide dismutase conjugated to polyethylene glycol fails to limit myocardial infarct size after 30 min ischemia followed by 72 h of reperfusion in the rabbit
    • 10. Ooiwa H, Stanley A, Felaneous-Bylund AC, Wilborn W, Downey JM. Superoxide dismutase conjugated to polyethylene glycol fails to limit myocardial infarct size after 30 min ischemia followed by 72 h of reperfusion in the rabbit. J. Mol. Cell. Cordiol. 1991; 23: 119-25.
    • (1991) J. Mol. Cell. Cordiol. , vol.23 , pp. 119-125
    • Ooiwa, H.1    Stanley, A.2    Felaneous-Bylund, A.C.3    Wilborn, W.4    Downey, J.M.5
  • 11
    • 0027421367 scopus 로고
    • Hyperbaric oxygen limits infarct size in ischemic rabbit myocardium in vivo
    • 11. Sterling DL, Thornton JD, Swafford A et al. Hyperbaric oxygen limits infarct size in ischemic rabbit myocardium in vivo. Circulation 1993; 88: 1931-6.
    • (1993) Circulation , vol.88 , pp. 1931-1936
    • Sterling, D.L.1    Thornton, J.D.2    Swafford, A.3
  • 12
    • 0024600283 scopus 로고
    • Effect of superoxide dismutase on myocardial infarct size in the canine heart after 6 hours of regional ischemia and reperfusion: A demonstration of myocardial salvage
    • 12. Chi L, Tamura Y, Hoff PT et al. Effect of superoxide dismutase on myocardial infarct size in the canine heart after 6 hours of regional ischemia and reperfusion: A demonstration of myocardial salvage. Circ. Res. 1989; 64: 665-75.
    • (1989) Circ. Res. , vol.64 , pp. 665-675
    • Chi, L.1    Tamura, Y.2    Hoff, P.T.3
  • 13
    • 0027254168 scopus 로고
    • Superoxide dismutase plus catalase therapy delays neither cell death nor the loss of the TTC reaction in experimental myocardial infarction in dogs
    • 13. Tanaka M, Richard VJ, Murry CE, Jennings RB, Reimer KA. Superoxide dismutase plus catalase therapy delays neither cell death nor the loss of the TTC reaction in experimental myocardial infarction in dogs. J. Mol. Cell. Cardiol. 1993; 25: 367-78.
    • (1993) J. Mol. Cell. Cardiol. , vol.25 , pp. 367-378
    • Tanaka, M.1    Richard, V.J.2    Murry, C.E.3    Jennings, R.B.4    Reimer, K.A.5
  • 14
    • 0027255026 scopus 로고
    • Myocardial preservation by therapy with coenzyme Q10 during heart surgery
    • 14. Judy WV, Stogsdill WW, Folkers K. Myocardial preservation by therapy with coenzyme Q10 during heart surgery. Clin. Invest. 1993; 71 (Suppl. 8): S155-61.
    • (1993) Clin. Invest. , vol.71 , Issue.SUPPL. 8
    • Judy, W.V.1    Stogsdill, W.W.2    Folkers, K.3
  • 15
    • 0026493797 scopus 로고
    • Lidocaine: A hydroxyl radical scavenger and singlet oxygen quencher
    • 15. Das KC, Mistra HP. Lidocaine: A hydroxyl radical scavenger and singlet oxygen quencher. Mol. Cell. Biochem. 1992; 115: 179-85.
    • (1992) Mol. Cell. Biochem. , vol.115 , pp. 179-185
    • Das, K.C.1    Mistra, H.P.2
  • 16
    • 0028346253 scopus 로고
    • Marked reduction in myocardial infarct size due to prolonged infusion of an antioxidant during reperfusion
    • 16. Howitz LD, Fennessey PV, Shikes RH, Kong Y. Marked reduction in myocardial infarct size due to prolonged infusion of an antioxidant during reperfusion. Circulation 1994; 89: 1792-801.
    • (1994) Circulation , vol.89 , pp. 1792-1801
    • Howitz, L.D.1    Fennessey, P.V.2    Shikes, R.H.3    Kong, Y.4
  • 17
    • 0015530358 scopus 로고
    • The occurrence of superoxide anion in the reaction of reduced phenazine methosulfate and molecular oxygen
    • 17. Nishiki M, Rao NA, Yagi K. The occurrence of superoxide anion in the reaction of reduced phenazine methosulfate and molecular oxygen. Biochem. Biophys. Res. Commun. 1972; 46: 849-54.
    • (1972) Biochem. Biophys. Res. Commun. , vol.46 , pp. 849-854
    • Nishiki, M.1    Rao, N.A.2    Yagi, K.3
  • 20
    • 0025758874 scopus 로고
    • Detection of hydroxyl radicals in the postischemic reperfused heart using salicylate as a trapping agent
    • 20. Onodera T, Ashraf M. Detection of hydroxyl radicals in the postischemic reperfused heart using salicylate as a trapping agent. J. Mol. Cell. Cardiol. 1991; 23: 365-70.
    • (1991) J. Mol. Cell. Cardiol. , vol.23 , pp. 365-370
    • Onodera, T.1    Ashraf, M.2
  • 21
    • 0021733759 scopus 로고
    • Sensitive assay of hydroxyl free radical formation utilizing high pressure liquid chromatography with electro-chemical detection of phenol and salicylate hydroxylation products
    • 21. Floyd RA, Watson JJ, Wong PK. Sensitive assay of hydroxyl free radical formation utilizing high pressure liquid chromatography with electro-chemical detection of phenol and salicylate hydroxylation products. J. Biochem. Biophys. Methods 1984; 10: 221-35.
    • (1984) J. Biochem. Biophys. Methods , vol.10 , pp. 221-235
    • Floyd, R.A.1    Watson, J.J.2    Wong, P.K.3
  • 22
    • 0022448732 scopus 로고
    • Aromatic hydroxylation as a potential measure of hydroxyl-radical formation in vivo
    • 22. Grootvelt M, Halliwell B. Aromatic hydroxylation as a potential measure of hydroxyl-radical formation in vivo. Biochem. J. 1986; 237: 499-504.
    • (1986) Biochem. J. , vol.237 , pp. 499-504
    • Grootvelt, M.1    Halliwell, B.2
  • 23
    • 0025733745 scopus 로고
    • Hydroxylation of salicylate as an assay for hydroxyl radicals: A cautionary report
    • 23. Halliwell B, Kauer H, Ingelman-Sundberg M. Hydroxylation of salicylate as an assay for hydroxyl radicals: A cautionary report. Free Rad. Biol. Med. 1991; 10: 439-41.
    • (1991) Free Rad. Biol. Med. , vol.10 , pp. 439-441
    • Halliwell, B.1    Kauer, H.2    Ingelman-Sundberg, M.3
  • 24
    • 0023709360 scopus 로고
    • Superoxide dismutase conjugated to polyethylene glycol provides sustained protection against myocardial ischemia/reperfusion injury in canine heart
    • 24. Tamura Y, Chi L, Driscoll EM et al. Superoxide dismutase conjugated to polyethylene glycol provides sustained protection against myocardial ischemia/reperfusion injury in canine heart. Circ. Res. 1988; 63: 944-59.
    • (1988) Circ. Res. , vol.63 , pp. 944-959
    • Tamura, Y.1    Chi, L.2    Driscoll, E.M.3
  • 25
    • 0024995105 scopus 로고
    • Evidence against the 'early protection-delayed death' hypothesis of superoxide dismutase therapy in experimental myocardial infarction
    • 25. Tanaka M, Stoler RC, FitzHarris GP, Jennings RB, Reimer KA. Evidence against the 'early protection-delayed death' hypothesis of superoxide dismutase therapy in experimental myocardial infarction. Circ. Res. 1990; 67: 636-44.
    • (1990) Circ. Res. , vol.67 , pp. 636-644
    • Tanaka, M.1    Stoler, R.C.2    FitzHarris, G.P.3    Jennings, R.B.4    Reimer, K.A.5
  • 26
    • 0025542037 scopus 로고
    • Time course of endothelial dysfunction and myocardial injury during myocardial ischemia and reperfusion in the cat
    • 26. Tsao PS, Aoki N, Lefer DJ, Johnson G III, Lefer AM. Time course of endothelial dysfunction and myocardial injury during myocardial ischemia and reperfusion in the cat. Circulation 1990; 82: 1402-12.
    • (1990) Circulation , vol.82 , pp. 1402-1412
    • Tsao, P.S.1    Aoki, N.2    Lefer, D.J.3    Johnson G. III4    Lefer, A.M.5
  • 27
    • 0022774380 scopus 로고
    • Canine myocardial reperfusion injury: Protection by a free radical scavenger, N-2-mercaptopropionyl glycine
    • 27. Mitsos SE, Fantone JC, Gallagher KP et al. Canine myocardial reperfusion injury: Protection by a free radical scavenger, N-2-mercaptopropionyl glycine. J. Cardiovasc. Pharmacol. 1986; 8: 978-88.
    • (1986) J. Cardiovasc. Pharmacol. , vol.8 , pp. 978-988
    • Mitsos, S.E.1    Fantone, J.C.2    Gallagher, K.P.3
  • 29
    • 0027745856 scopus 로고
    • Quantitative assessment of free-radical generation during ischemia and reperfusion in the isolated rabbit heart
    • 29. Premaratne S, Limm W, Mugiishi MM, Piette LH, McNamara JJ. Quantitative assessment of free-radical generation during ischemia and reperfusion in the isolated rabbit heart. Coron. Art. Dis. 1993; 4: 1093-6.
    • (1993) Coron. Art. Dis. , vol.4 , pp. 1093-1096
    • Premaratne, S.1    Limm, W.2    Mugiishi, M.M.3    Piette, L.H.4    McNamara, J.J.5
  • 30
    • 0028290755 scopus 로고
    • Reduced production of the deleterious hydroxyl free radical during the final reperfusion of isolated rabbit heart with the use of an improved sodium lactobionate-based cardioplegic medium
    • 30. Charloux C, Ishii K, Paul M, Loisance D, Astier A. Reduced production of the deleterious hydroxyl free radical during the final reperfusion of isolated rabbit heart with the use of an improved sodium lactobionate-based cardioplegic medium. J. Heart Lung Transplant. 1994; 13: 481-8.
    • (1994) J. Heart Lung Transplant. , vol.13 , pp. 481-488
    • Charloux, C.1    Ishii, K.2    Paul, M.3    Loisance, D.4    Astier, A.5
  • 31
    • 0030962051 scopus 로고    scopus 로고
    • Continuous detection of superoxide in situ during ischemia and reperfusion in the rabbit heart
    • 31. Ushiroda S, Maruyama Y, Nakano M. Continuous detection of superoxide in situ during ischemia and reperfusion in the rabbit heart. Jpn. Heart J. 1997; 38: 91-105.
    • (1997) Jpn. Heart J. , vol.38 , pp. 91-105
    • Ushiroda, S.1    Maruyama, Y.2    Nakano, M.3
  • 32
    • 0025232708 scopus 로고
    • Detection of oxygen-derived free radical generation in the canine postischemic heart during late phase of reperfusion
    • 32. Kuzuya T, Hoshida S, Kim Y et al. Detection of oxygen-derived free radical generation in the canine postischemic heart during late phase of reperfusion. Circ. Res. 1990; 66: 1160-5.
    • (1990) Circ. Res. , vol.66 , pp. 1160-1165
    • Kuzuya, T.1    Hoshida, S.2    Kim, Y.3
  • 33
    • 0028308540 scopus 로고
    • Antioxidant effectiveness in ischemia-reperfusion tissue injury
    • 33. Das DK, Maulik N. Antioxidant effectiveness in ischemia-reperfusion tissue injury. Methods Enzymol. 1994; 233: 601-10.
    • (1994) Methods Enzymol. , vol.233 , pp. 601-610
    • Das, D.K.1    Maulik, N.2
  • 34
    • 0032508594 scopus 로고    scopus 로고
    • Potentiation of nitric oxide synthase expression by superoxide in interleukin-1beta-stimulated rat mesangial cells
    • 34. Beck KF, Eberhardt W, Walpen S, Apel M, Pfeilschifter J, Potentiation of nitric oxide synthase expression by superoxide in interleukin-1beta-stimulated rat mesangial cells. FEBS Lett. 1998; 435: 35-8.
    • (1998) FEBS Lett. , vol.435 , pp. 35-38
    • Beck, K.F.1    Eberhardt, W.2    Walpen, S.3    Apel, M.4    Pfeilschifter, J.5
  • 35
    • 0031931907 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase augments injury elicited by oxidative stress in rat cardiac myocytes
    • 35. Igarashi J, Nishida M, Hoshida S et al. Inducible nitric oxide synthase augments injury elicited by oxidative stress in rat cardiac myocytes. Am. J. Physiol. 1998; 274: C245-52.
    • (1998) Am. J. Physiol. , vol.274
    • Igarashi, J.1    Nishida, M.2    Hoshida, S.3
  • 37
    • 0029907565 scopus 로고    scopus 로고
    • Free radicals in reperfusion-induced arrythmias: Study with EUK8, a novel nonprotein catalytic antioxidant
    • 37. Tanguy S, Boucher FR, de Malfroy B, Leiris JG. Free radicals in reperfusion-induced arrythmias: Study with EUK8, a novel nonprotein catalytic antioxidant. Free Rad. Biol. Med. 1996; 21: 945-54.
    • (1996) Free Rad. Biol. Med. , vol.21 , pp. 945-954
    • Tanguy, S.1    Boucher, F.R.2    De Malfroy, B.3    Leiris, J.G.4
  • 39
    • 0026593813 scopus 로고
    • The failure of radical scavengers to attenuate the incidence of reperfusion arrhythmias despite improvement of cardiac function
    • 39. Minezaki KK, Nakazawa H, Shinozaki Y, Ichimori K, Okino H. The failure of radical scavengers to attenuate the incidence of reperfusion arrhythmias despite improvement of cardiac function. Heart Vessels 1992; 7: 31-6.
    • (1992) Heart Vessels , vol.7 , pp. 31-36
    • Minezaki, K.K.1    Nakazawa, H.2    Shinozaki, Y.3    Ichimori, K.4    Okino, H.5
  • 40
    • 0028857569 scopus 로고
    • Role of oxygen-derived free radicals in canine reperfusion arrhythmias
    • 40. Euler DE. Role of oxygen-derived free radicals in canine reperfusion arrhythmias. Am. J. Physiol. 1995; 268: H295-300.
    • (1995) Am. J. Physiol. , vol.268
    • Euler, D.E.1
  • 41
    • 0027213897 scopus 로고
    • Reperfusion arrhythmias and purine wash-out in isolated rat and rabbit heart. Effect of allopurinol, dimethylthiourea and calcium reduction
    • 41. Kopacz M, Karwatowska-Prokopczuk E, Beresewicz A. Reperfusion arrhythmias and purine wash-out in isolated rat and rabbit heart. Effect of allopurinol, dimethylthiourea and calcium reduction. J. Mol. Cell. Cardiol. 1993; 25: 859-74.
    • (1993) J. Mol. Cell. Cardiol. , vol.25 , pp. 859-874
    • Kopacz, M.1    Karwatowska-Prokopczuk, E.2    Beresewicz, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.