Procalcitonin and C-reactive protein: Comparison of two markers for sepsis-syndrom in severely immunocompromised children after bone marrow transplantation;Procalcitonin im vergleich zum C-reaktiven protein als marker fur septische krankheitsverlaufe bei schwer immunsupprimierten kindern nach knochenmarktransplantation

Klinische Padiatrie

Volumn 212, Issue 1, 2000, Pages 10-15

  Sauer, M ^a   Tiede, K ^b   Volland, R ^b   Fuchs, D ^b   Zintl, F ^b  

^a UNIVERSITY OF MINNESOTA   (United States)

^b NONE

Author keywords

Bone marrow transplantation; C reactive protein; Children; Procalcitonin; Sepsis; Sepsis syndrome

Indexed keywords

C REACTIVE PROTEIN; PROCALCITONIN;

ARTICLE; BONE MARROW TRANSPLANTATION; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; DIAGNOSTIC VALUE; DISEASE MARKER; HUMAN; IMMUNE DEFICIENCY; PROGNOSIS; SEPSIS;

ADOLESCENT; ADULT; BIOLOGICAL MARKERS; BONE MARROW TRANSPLANTATION; C-REACTIVE PROTEIN; CALCITONIN; CHILD; CHILD, PRESCHOOL; FEMALE; GLYCOPROTEINS; HUMANS; IMMUNOCOMPROMISED HOST; MALE; PREDICTIVE VALUE OF TESTS; PROSPECTIVE STUDIES; PROTEIN PRECURSORS; RISK ASSESSMENT; SENSITIVITY AND SPECIFICITY; SEPSIS; SEVERITY OF ILLNESS INDEX; SURVIVAL ANALYSIS;

EID: 0034093279     PISSN: 03008630     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2000-9644     Document Type: Article

References (30)

1. 1 Al-Nawas B, Krammer I, Sah PM et al. Procalcitonin in the diagnosis of severe infections. Eur J Med Res 1996; 1: 331-333
2. 2 Antonelli M, Raponi GM, Martino P. High IL-6 levels are associated with septic shock and mortality in septic patients with severe leukopenia due to hematological malignancies. Scand J Infect Dis 1995; 27: 381 -384
3. 3 Assicot M, Gendrel D, Carsin H. High serum procalcitonon concentrations in patients with sepsis and infection. Lancet 1993; 341: 515-518
4. 4 Becker KL, O'Neill W, Snider RH. Hypercalcitonin-emia in inhalation burn injury: A response of the pulmonary endocrine cell? Anatomic Record 1993; 236: 136-138
5. 5 Bone R, Fisher C, Cemmer T. Sepsis syndrome: a valid clinical entity. Methylprednisolone Severe Sepsis Study Group. Crit Care Med 1989; 17: 389-393
6. 6 Brunkhorst FM, Forycki ZF, Wagner J. Release and kinetics of procalcitonin (PCT after gram-negativ bacterial injection in a healthy subject. Shock 1997; 7: 124 (Abst)
7. 7 Dandona P, Nix D, Wilson MF. Procalcironin increase after endotoxin injection in normal subjects. J Ctin Endocrinol Metab 1994; 79: 1605-1608
8. 8 De Werra I, Jaccard C, Corradin SB. Cytokines, nitrite/nitrate, soluble tumor necrosis factor receptors, and procalcitonin concentrations: Comparison in patients with septic shock, cardiogenic shock, and bacterial pneumonia. Crit Care Med 1997; 25: 607-613
9. 9 Enright H, Coyle M, O'Connel L. CRP Concentration pre-and post transfusion. Clin Lab Haematol 1990; 12: 25-29
10. 10 Erikson S, Grantstom L, Olander BJ. Sensitivity of interleukin-6 and C-reactive protein concentrations in the diagnosis of acute appendicitis. Eur J Surg 1995; 161: 41 -45
11. 11 Gerard Y, Hober D, Petitjean S, Assicot M. High serum procalcitonin level in a 4-year-old liver transplant recipient with a disseminated candidiasis. Infection 1995; 23: 310-311
12. 12 Gerard Y, Hober D, Assicot M. Procalcitonin as a marker of bacterial sepsis in patients infected with HIV 1. J Infect 1997; 35: 41-46
13. 13 Gramm HJ, Reinhart K, Goecke J. Early clinical, laboratory, and hemodynamic indicators of sepsis and septic shock. In: Reinhart K, Eyrich K (eds.): Sepsis - An interdisiplinary Challenge. Springer Verlag, Berlin 1989; pp 45-57
14. 14 Groll A, Müller FM. Fortschritte in Pravention und Therapie infektiöser Komplikationen bei Kindern und Jugendlichen mit neoplastischen Erkrankungen. Klin Pädiatr 1998; 210: 106-114
15. 15 Hammer C, Staehler M. Procalcitonin (PCT), a new marker for differential diagnosis of acute rejection of and bacterial infection of heart transplanted patients. Clinical Intensive Care 7: 1996; S39 (Abstract)
16. 16 Jackson SR, Tweeddale MG, Barnett MT. Admission for bone marrow transplant recipients to the intensiv care unit: outcome, survival and prognostic factors. Bone marrow Transplantation 1998; 21(7): 697-704
17. 17 Kragsberbjer P, Holmberg H, Vikefors T. Serum concentrations of interleukin-6, tumor necrosis factor-alpha and C-reactive protein in patients undergoing major operations. Eur J Surg 1995; 161: 17-22
18. 18 Le Moullec JM, Jullienne A, Chenais J. The complete sequence of preprocalcitonin. FEBS 1984; 67: 93-97
19. 19 Leser HG, Gross V, Scheibenbogen C. Elevation of serum interleukin-6 concentrations precedes acute phase response and reflects severity of acute pancreatitis. Gastroenterology 1991; 101:782-785
20. 20 Manian F. A prospective study of daily measurement of CRP in serum of adults with neutropenia. Clinical Infect Dis 1995; 21: 114-121
21. 21 Meisner M, Tschaikowsky K, Schmidt J. Procalcitonin (PCT) -Indications for a new diagnostic parameter of severe bacterial infection and sepsis in transplantation, immunsuppression and cardiac assist devices. Cardiovascular Engineering 1997; 1: 67-76
22. 22 Monneret G, Labaune JM, Isaac C. Procalcitonin and C-reactive protein levels in neonatal infections. Acta Pediatr 1997; 86: 209-212
23. 23 Oberhoffer M, Bögel D, Meier-Hellmann A. Procalcitonin vs immunological markers in infection/inflammation. Br J Anaesth 1996; 76: A348 (Abstract)
24. 24 Oberhoffer M, Vogelsang H, Meier Hellmann A. Anti-Katacalcin-antibody-reaction in different types of human leucococytes indicates procalcitonon content. Shock 1997; 7: 487 (Abstract)
25. 25 Rintala E, Pulkki K, Mertsola J. Endotoxin, interleukin-6, and phospholipase-A2 as markers of sepsis in patients with hematological malignancies. Scand J Infect Dis 1995; 27: 39-43
26. 26 Ruescher TJ, Sodeifi A, Scrivani SJ. The impact of mucositis on alpha-hemolytic streptococcal infection in patients undergoing autologous bone marrow transplantations for hematolgic malignancies. Cancer 1998; 82(11): 2275-2281
27. 27 Shaw AC. Serum C-reactive protein and neopterin concentrations in patients with viral or bacterial infection. J Clin Pathol 1991; 44: 596-599
28. 28 Smith MD, Suputtamongkol Y, Chaowagul W. Elevated serum Procalcitonin levels in patients with melioidosis. Clin Infect Dis 1995; 20: 641 -645
29. 29 Smith RP, Lipworth BJ. C-reactive protein in simple community acquired pneumonia. Chest 1995; 107: 1028-1031
30. 30 Zintl F, Sauer M, Fuchs D et al.. High Serum Procalcitonin (PCT) Concentrations in children and adults after hematopoietic stem cell transplantation - an indicator for poor prognosis in severe infections Blood 1996; 88: 3791 (Abstract)