Split ends encodes large nuclear proteins that regulate neuronal cell fate and axon extension in the Drosophila embryo

Development

Volumn 127, Issue 7, 2000, Pages 1517-1529

  Kuang, Bing ^a   Wu, Sareina C Y ^a   Shin, Young Ah ^a   Luo, Liqun ^b   Kolodziej, Peter ^a  

^a VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^b STANFORD UNIVERSITY   (United States)

Author keywords

EGF receptor; Notch; Ras; RRM; Spen; Su(H)

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; NUCLEAR PROTEIN; REPRESSOR PROTEIN; TRANSCRIPTION FACTOR;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL FATE; CELL PROLIFERATION; CELL STRUCTURE; CONTROLLED STUDY; DROSOPHILA; EMBRYO; EMBRYO DEVELOPMENT; FEMALE; GENE FUNCTION; MALE; NERVE CELL DIFFERENTIATION; NERVE FIBER; NERVE GROWTH; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN FAMILY; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; ZYGOTE;

AMINO ACID SEQUENCE; ANIMALS; AXONS; CLONING, MOLECULAR; CONSERVED SEQUENCE; DROSOPHILA; DROSOPHILA PROTEINS; EVOLUTION, MOLECULAR; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HOMEODOMAIN PROTEINS; INSECT PROTEINS; MOLECULAR SEQUENCE DATA; MUTATION; NEURONS; NUCLEAR PROTEINS; PROTEIN STRUCTURE, TERTIARY; RNA-BINDING PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; STEM CELLS;

ANIMALIA; ARACHNIDA; HEXAPODA; INSECTA; VERTEBRATA;

EID: 0034092939     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (66)

1. Altschul, S. F., Gish, W., Miller, W., Myers, E. W. and Lipman, D. J. (1990). Basic local alignment search tool. J. Mol. Biol. 215, 403-410.
2. Artavanis-Tsakonas, S., Rand, M. D. and Lake, R. J. (1999). Notch signaling: cell fate control and signal integration in development. Science 284, 770-776.
3. Bailey, A. M. and Posakony, J. W. (1995). Suppressor of hairless directly activates transcription of enhancer of split complex genes in response to Notch receptor activity. Genes Dev. 9, 2609-2622.
4. Bertolotti, A., Lutz, Y., Heard, D. J., Chambon, P. and Tora, L. (1996). hTAF(II)68, a novel RNA/ssDNA-binding protein with homology to the prooncoproteins TLS/FUS and EWS is associated with both TFIID and RNA polymerase II. EMBO J. 15, 5022-5031.
5. Bier, E., Jan, L. Y. and Jan, Y. N. (1990). rhomboid, a gene required for dorsoventral axis establishment and peripheral nervous system development in Drosophila melanogaster. Genes Dev. 4, 190-203.
6. Brown, N. H. and Kafatos, F. C. (1988). Functional cDNA libraries from Drosophila embryos. J. Mol. Biol. 203, 425-437.
7. Burd, C. G. and Dreyfuss, G. (1994). Conserved structures and diversity of RNA-hinding proteins. Science 265, 615-621.
8. Campos-Ortega, J. A. (1995). Genetic mechanisms of early neurogenesis in Drosophila melanogaster. Mol. Neurobiol. 10, 75-89.
9. Campos-Ortega, J. A. and Hartenstein, V. (1985). The Embryonic Development of Drosophila melanogaster. Springer-Verlag, New York, NY, USA.
10. Chou, T. B. and Perrimon, N. (1996). The autosomal FLP-DFS technique for generating germline mosaics in Drosophila melanogaster. Genetics 144, 1673-1679.
11. DeAngelo, D. J., DeFalco, J., Rybacki, L. and Childs, G. (1995). The embryonic enhancer-binding protein SSAP contains a novel DNA-binding domain which has homology to several RNA-binding proteins. Mol. Cell Biol. 15, 1254-1264.
12. Dickson, B. J., van der Straten, A., Dominguez, M. and Hafen, E. (1996). Mutations modulating Raf signaling in Drosophila eye development. Genetics 142, 163-171.
13. Doe, C. Q., Hiromi, Y., Gehring, W. J. and Goodman, C. S. (1988a). Expression and function of the segmentation gene fushi tarazu during Drosophila neurogenesis. Science 239, 170-175.
14. Doe, C. Q., Smouse, D. and Goodman, C. S. (1988b). Control of neuronal fate by the Drosophila segmentation gene even-skipped. Nature 333, 376-378.
15. Florence, B. and McGinnis, W. (1998). A genetic screen of the Drosophila X chromosome for mutations that modify Deformed function. Genetics 150, 1497-1511.
16. Fortini, M. E. and Artavanis-Tsakonas, S. (1994). The suppressor of hairless protein participates in notch receptor signaling. Cell 79, 273-282.
17. Fujita, S. C., Zipursky, S. L., Benzer, S., Ferrus, A. and Shotwell, S. L. (1982). Monoclonal antibodies against the Drosophila nervous system. Proc. Natl. Acad. Sci. USA 79, 7929-7933.
18. Gabay, L., Scholz, H., Golembo, M., Klaes, A., Shilo, B. Z. and Klambt, C. (1996). EGF receptor signaling induces pointed P1 transcription and inactivates Yan protein in the Drosophila embryonic ventral ectoderm. Development 122, 3355-3362.
19. Gabay, L., Seger, R. and Shilo, B. Z. (1997). In situ activation pattern of Drosophila EGF receptor pathway during development. Science 211, 1103-1106.
20. Gao, F. B. and Keene, J. D. (1996). Hel-N1/Hel-N2 proteins are bound to poly(A)+ mRNA in granular RNP structures and are implicated in neuronal differentiation. J. Cell Sci. 109, 579-589.
21. Gellon, G., Harding, K. W., McGinnis, N., Martin, M. M. and McGinnis, W. (1997). A genetic screen for modifiers of Deformed homeotic function identifies novel genes required for head development. Development 124, 3321-3331.
22. Giniger, E. (1998). A role for Abl in Notch signaling. Neuron 20, 667-681.
23. Giniger, E., Jan, L. Y. and Jan, Y. N. (1993a). Specifying the path of the intersegmental nerve of the Drosophila embryo: a role for Delta and Notch. Development 117, 431-440.
24. Giniger, E., Wells, W., Jan, L. Y. and Jan, Y. N. (1993b). Tracing neurons with a kinesin-β-galactosidase marker. Wilhelm Roux's Arch. Dev. Biol. 202, 112-122.
25. Gould, A. P. and White, R. A. (1992). Connectin, a target of homeotic gene control in Drosophila. Development 116, 1163-1174.
26. Hartenstein, A. Y., Rugendorff, A., Tepass, U. and Hartenstein, V. (1992). The function of the neurogenic genes during epithelial development in the Drosophila embryo. Development 116, 1203-1220.
27. Jan, Y. N. and Jan, L. Y. (1994). Genetic control of cell fate specification in Drosophila peripheral nervous system. Annu. Rev. Genet. 28, 373-393.
28. Jarman, A. P., Grau, Y., Jan, L. Y. and Jan, Y. N. (1993). atonal is a proneural gene that directs chordotonal organ formation in the Drosophila peripheral nervous system. Cell 73, 1307-1321.
29. Jarman, A. P., Sun, Y., Jan, L. Y. and Jan, Y. N. (1995). Role of the proneural gene, atonal, in formation of Drosophila chordotonal organs and photoreceptors. Development 121, 2019-2030.
30. Kolodziej, P. A., Jan, L. Y. and Jan, Y. N. (1995). Mutations that affect the length, fasciculation, or ventral orientation of specific sensory axons in the Drosophila embryo. Neuron 15, 273-286.
31. Lage, P., Jan, Y. N. and Jarman, A. P. (1997). Requirement tor EGF receptor signalling in neural recruitment during formation of Drosophila chordotonal sense organ clusters. Curr. Biol. 7, 166-175.
32. Lai, Z. C. and Rubin, G. M. (1992). Negative control of photoreceptor development in Drosophila by the product of the yan gene, an ETS domain protein Cell 70, 609-620.
33. Landgraf, M., Bossing, T., Technau, G. M. and Bate, M. (1997). The origin, location, and projections of the embryonic abdominal motorneurons of Drosophila. J. Neurosci. 17, 9642-9655.
34. Landgraf, M., Roy, S., Prokop, A., VijayRaghavan, K. and Bate, M. (1999). even-skipped determines the dorsal growth of motor axons in Drosophila. Neuron 22, 43-52.
35. Lecourtois, M. and Schweisguth, F. (1995). The neurogenic suppressor of hairless DNA-binding protein mediates the transcriptional activation of the enhancer of split complex genes triggered by Notch signaling. Genes Dev. 9, 2598-2608.
36. Lee, S., Harris, K. W., Whitington, P. and Kolodziej, P. A. (2000). short stop is allelic to kakapo, and encodes a family of rodlike cytoskeletal associated proteins required for axon growth. J. Neurosci. 20, 1096-1108.
37. Martin-Bermudo, M. D., Carmena, A. and Jimenez, F. (1995). Neurogenic genes control gene expression at the transcriptional level in early neurogenesis and in mesectoderm specification. Development 121, 219-224.
38. Menne, T. V. and Klambt, C. (1994). The formation of commissures in the Drosophila CNS depends on the midline cells and on the Notch gene. Development 120, 123-133.
39. Mitchison, T. J. and Sedat, J. (1983). Localization of antigenic determinants in whole Drosophila embryos. Dev. Biol. 99, 261-264.
40. Nambu, J. R., Lewis, J. O., Wharton, K. A., Jr. and Crews, S. T. (1991). The Drosophila single-minded gene encodes a helix-loop-helix protein that acts as a master regulator of CNS midline development. Cell 67, 1157-1167.
41. Newberry, E. P., Latifi, T. and Towler, D. A. (1999). The RRM domain of MINT, a novel Msx2 binding protein, recognizes and regulates the rat osteocalcin promoter. Biochemistry 38, 10678-10690.
42. O'Neill, E. M., Rebay, I., Tjian, R. and Rubin, G. M. (1994). The activities of two Ets-related transcription factors required for Drosophila eye development are modulated by the Ras/MAPK pathway. Cell 78, 137-147.
43. Okabe, M. and Okano, H. (1997). Two-step induction of chordotonal organ precursors in Drosophila embryogenesis. Development 124, 1045-1053.
44. Orita, M., Iwahana, H., Kanazawa, H., Hayashi, K. and Sekiya, T. (1989). Detection of polymorphisms of human DNA by gel electrophoresis as single-strand conformation polymorphisms. Proc. Natl. Acad. Sci. USA 86, 2766-2770.
45. Patel, N. H., Martin-Blanco, E., Coleman, K. G., Poole, S. J., Ellis, M. C., Kornberg, T. B. and Goodman, C. S. (1989). Expression of engrailed proteins in arthropods, annelids, and chordates. Cell 58, 955-968.
46. Rebay, I., Chen, F., Hsiao, F., Kolodziej, P. A., Kuang, B., Laverty, T., Suh, C., Voas, M., Williams, A. and Rubin, G. (2000). A genetic screen for novel components of the Ras/MAPK signaling pathway that interact with the yan gene of Drosophila identifies split ends, a new RRM motif containing protein. Genetics 154, 695-712.
47. Rebay, I. and Rubin, G. M. (1995). Yan functions as a general inhibitor of differentiation and is negatively regulated by activation of the Ras1/MAPK pathway. Cell 81, 857-866.
48. Robertson, H. M., Preston, C. R., Phillis, R. W., Johnson-Schlitz, D. M., Benz, W. K. and Engels, W. R. (1988). A stable genomic source of P element transposase in Drosophila melanogaster. Genetics 118, 461-470.
49. Robinow, S. and White, K. (1991). Characterization and spatial distribution of the ELAV protein during Drosophila melanogasier development. J. Neurobiol. 22, 443-461.
50. Rogge, R., Green, P. J., Urano, J., Horn-Saban, S., Mlodzik, M., Shilo, B. Z., Hartenstein, V. and Banerjee, U. (1995). The role of yan in mediating the choice between cell division and differentiation. Development 121, 3947-3958.
51. Rutledge, B. J., Zhang, K., Bier, E., Jan, Y. N. and Perrimon, N. (1992). The Drosophila spitz gene encodes a putative EGF-like growth factor involved in dorsal-ventral axis formation and neurogenesis. Genes Dev. 6, 1503-17.
52. Scholz, H., Sadlowski, E., Klaes, A. and Klambt, C. (1997). Control of midline glia development in the embryonic Drosophila CNS. Mech. Dev. 64, 137-151.
53. Seeger, M., Tear, G., Ferres-Marco, D. and Goodman, C. S. (1993). Mutations affecting growth cone guidance in Drosophila: genes necessary for guidance toward or away from the midline. Neuron 10, 409-426.
54. Sestan, N., Artavanis-Tsakonas, S. and Rakic, P. (1999). Contact-Dependent Inhibition of Cortical Neurite Growth Mediated by Notch Signaling. Science 286, 741-746.
55. Siegler, M. V. and Jia, X. X. (1999). Engrailed negatively regulates the expression of cell adhesion molecules connectin and neuroglian in embryonic Drosophila nervous system. Neuron 22, 265-276.
56. Sink, H. and Whitington, P. M. (1991). Location and connectivity of abdominal motoneurons in the embryo and larva of Drosophila melanogaster. J. Neurobiol. 22, 298-311.
57. Skeath, J. B. and Doe, C. Q. (1996). The achaete-scute complex proneural genes contribute to neural precursor specification in the Drosophila CNS. Curr. Biol. 6, 1146-1152.
58. Staehling-Hampton, K., Ciampa, P. J., Brook, A. and Dyson, N. (1999). A genetic screen for modifiers of E2F in Drosophila melanogaster. Genetics 153, 275-287.
59. Sun, Y., Jan, L. Y. and Jan, Y. N. (1998). Transcriptional regulation of atonal during development of the Drosophila peripheral nervous system. Development 125, 3731-3740.
60. Tessier-Lavigne, M. and Goodman, C. S. (1996). The molecular biology of axon guidance. Science 274, 1123-1133.
61. Thomas, J. B., Crews, S. T. and Goodman, C. S. (1988). Molecular genetics of the single-minded locus: a gene involved in the development of the Drosophila nervous system. Cell 52, 133-141.
62. Van Vactor, D. V., Sink, H., Fambrough, D., Tsoo, R. and Goodman, C. S. (1993). Genes that control neuromuscular specificity in Drosophila. Cell 73, 1137-1153.
63. Wiellette, E. L., Harding, K. W., Mace, K. A., Ronshaugen, M. R., Wang, F. Y. and McGinnis, W. (1999). Spen encodes an RNP motif protein that interacts with Hox pathways to repress the development of head sclerites in the Drosophila trunk. Development 126, 5373-5385.
64. Xiong, W. C., Okano, H., Patel, N. H., Blendy, J. A. and Montell, C. (1994). repo encodes a glial-specific homeo domain protein required in the Drosophila nervous system. Genes Dev. 8, 981-994.
65. Zinn, K., McAllister, L. and Goodman, C. S. (1988). Sequence analysis and neuronal expression of fasciclin I in grasshopper and Drosophila. Cell 53, 577-587.
66. zur Lage, P. and Jarman, A. P. (1999). Antagonism of EGFR and notch signalling in the reiterative recruitment of Drosophila adult chordotonal sense organ precursors. Development 126, 3149-3157.