Xanthogranulomas with inconspicuous foam cells and giant cells mimicking malignant melanoma: A clinical, histologic, and immunohistochemical study of three cases

American Journal of Surgical Pathology

Volumn 24, Issue 6, 2000, Pages 864-869

  Busam, Klaus J ^b   Rosai, Juan ^c   Iversen, Kristin ^a   Jungbluth, Achim A ^a  

^a LUDWIG INSTITUTE FOR CANCER RESEARCH   (Australia)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^c NONE

Author keywords

Melanoma; Xanthogranuloma

Indexed keywords

BLOOD CLOTTING FACTOR 8A; CD68 ANTIGEN; GLYCOPROTEIN GP 100; MONOPHENOL MONOOXYGENASE; PROTEIN S 100;

ADOLESCENT; ADULT; AGED; ARTICLE; CASE REPORT; DIAGNOSTIC ERROR; FOAM CELL; GIANT CELL; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; MELANOMA; SKIN NODULE; XANTHOGRANULOMA;

ADOLESCENT; ADULT; AGED; BIOPSY; DIAGNOSIS, DIFFERENTIAL; GRANULOMA; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MELANOMA; SCALP DERMATOSES; SKIN; SKIN DISEASES; SKIN NEOPLASMS; XANTHOMATOSIS;

EID: 0034092411     PISSN: 01475185     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000478-200006000-00013     Document Type: Article

References (34)

1. Busam KJ, Chen YT, Old LJ, et al. Expression of Melan-A (MART-1) in benign melanocytic nevi and primary malignant melanoma. Am J Surg Pathol 1998;22:976-82.
2. Busam KJ, Iversen K, Coplan KA, et al. Immunoreactivity for A103, an antibody to Melan-A (MART-1), in adrenocortical and other steroid tumors. Am J Surg Pathol 1998;22:57-63.
3. Caputo R, Grimait R, Gelmetti C, Cottoni E. Unusual aspects of juvenile xanthogranuloma. J Am Acad Dermatol 1993;29:868-70.
4. Chen YT, Stocken E, Jungbluth AA, et al. Serologic analysis of Melan-A (MART-1), a melanocyte-specific protein homogeneously expressed in human melanomas. Proc Natl Acad Sci USA 1996;93:5915-9.
5. Chen YT, Stocken E, Tsang S, Coplan KA, Old LJ. Immunophenotyping of melanomas for tyrosinase: implications for vaccine development. Proc Natl Acad Sci USA 1995;92:8125-9.
6. Claudy Al, Misery L, Serre D, Boucheron S. Multiple juvenile xanthogranulomas without foam cells and giant cells. Pediatr Dermatol 1993:10:61-3.
7. Davies MG, Marks R. Multiple xanthogranulomata in an adult. Br J Dermatol 1977;97(suppl):70-2.
8. Gartmann H, Tritsch H. Klein-und grossknotiges Naevoxanthoenodothelioma. Dermatologica 1963;215:409-21.
9. Gloghini A, Rizzo A, Zanette I, et al. KP1/CD68 expression in malignant neoplasms including lymphomas, sarcomas, and carcinomas. Am J Clin Pathol 1995;103:425-31.
10. Glusac EJ, Barr RJ, Everett MA, Pitha J, Santa Cruz DJ. Epithelioid cell histiocytoma: a report of 10 cases including a new cellular variant. Am J Surg Pathol 1994;18:583-90.
11. Glusac EJ, McNiff JM. Epithelioid cell histiocytoma: a simulant of vascular and melanocytic neoplasms. Am J Dermatopathol 1999; 21:1-7.
12. Helwig EB, Hackney VC. Juvenile xanthogranuloma (nevoxanthoendothelioma). Am J Pathol 1954;30:625-6.
13. Hofbauer GF, Kamarshev J, Geertsen R, Boni R, Dummer R. Tyrosinase expression in formalin-fixed paraffin-embedded primary and metastatic melanoma: frequency and distribution. J Cutan Pathol 1998;25:204-9.
14. Jungbluth AA, Busam KJ, Chen TY. et al. A103 - an anti-Melan-A/MART-1 monoclonal antibody for the detection of malignant melanoma in paraffin embedded tissues. Am J Surg Pathol 1998;22:595-602.
15. Jungbluth AA, Iversen K, Coplan K, et al. Expression of melanocyte-associated markers gp-100 and Melan-A/MART-1 in angiomyolipomas. Virchows Arch 1999;434:429-35.
16. Kurtin PJ, Bonin DM. Immunohistochemical demonstration of the lysosome-associated glycoprotein CD68 (KP-1) in granular cell tumors and schwannomas. Hum Pathol 1994;25:1172-8.
17. Lieberman PH, Jones CR, Steinman RM, et al. Langerhans cell (eosinophilic) granulomatosis. A clinicopathologic study encompassing 50 years. Am J Surg Pathol 1996;20:519-52.
18. Marrogi AJ, Dehner LP, Coffin ChM, Wick MR. Benign cutaneous histiocytic tumors in childhood and adolescence, excluding Langerhans cell proliferations. Am J Dermatopathol 1992;14:8-18.
19. McNutt SN. The S-100 family of multipurpose calcium-binding proteins. J Cutan Pathol 1998;25:521-9.
20. Nakamura D, Izawa R, Nakayama K, Hoshi K, Onda S. Xanthogranuloma in the adult. J Dermatol 1983;10:151-6.
21. Oliver GF, Umbert I, Winkelmann RK. Reticulohistiocytoma cutis - review of 15 cases and an association with systemic vasculitis in two cases. Clin Exp Dermatol 1990;15:1-6.
22. Pineiro Maceira JM, Fukuyama K, Epstein WL, Rowden G. Immuno-histochemical demonstration of S-100 protein antigen-containing cells in beryllium-induced, zirconium-induced, and sarcoidosis granulomas. Am J Clin Pathol 1984;81:563-8.
23. Purvis WE III, Helwig EB. Reticulohistiocytic granuloma ('reticulohistiocytoma') of the skin. Am J Clin Pathol 1954;24:1005-15.
24. Rodriguez J, Ackerman AB. Xanthogranuloma in adults. Arch Dermatol 1976;112:43-4.
25. Sangueza OP, Salmon JK, White CR Jr, Beckstead JH. Juvenile xanthogranuloma: a clinical, histopathologic and immunohistochemical study. J Cutan Pathol 1995;22:327-35.
26. Seo IS, Min KW, Mirkin LD. Juvenile xanthogranuloma. Ultrastructural and immunocytochemical studies. Arch Pathol Lab Med 1986;110:911-5.
27. Shapiro PE, Silvers DN, Treiber RK, Cooper PH, True LD, Lattes R. Juvenile xanthogranulomas with inconspicuous or absent foam cells and giant cells. J Am Acad Dermatol 1991;24:1005-9.
28. Singh Gomez C, Calonje E, Fletcher CDM. Epithelioid benign fibrous histiocytoma of skin: clinico-pathological analysis of 20 cases of a poorly known variant. Histopathology 1994;24:123-9.
29. Sonoda T, Hashimoto H, Enjoji M. Juvenile xanthogranuloma. Clinicopathologic analysis and immunohistochemical study of 57 patients. Cancer 1985;56:2280-6.
30. Tahan SR, Pastel-Levy C, Bhan AK, Mihm MC Jr. Juvenile xanthogranuloma. Clinical and pathological characterization. Arch Pathol Lab Med 1989;113:1057-62.
31. Tanz WS, Kim YA, Schwartz RA, et al. Juvenile xanthogranuloma with inconspicuous foam cells and giant cells. Int J Dermatol 1995;34:653-5.
32. Tomaszewski M-M, Lupton GP. Unusual expression of S-100 protein in histiocytic neoplasms. J Cutan Pathol 1998;25:129-35.
33. Wilson Jones E, Cerio R, Smith NP. Epithelioid cell histiocytoma: a new entity. Br J Dermatol 1989;120:185-95.
34. Zelger B, Cerio R, Orchard G, Wilson-Jones E. Juvenile and adult xanthogranuloma. Am J Surg Pathol 1994;18:126-35.