Orally active cephalosporins. Part 2: Synthesis, structure-activity relationships and oral absorption of cephalosporins having a C-3 pyridyl side chain

Bioorganic and Medicinal Chemistry

Volumn 8, Issue 5, 2000, Pages 1159-1170

  Yamamoto, Hirofumi ^a   Terasawa, Takeshi ^a   Nakamura, Ayako ^a   Kawabata, Kohji ^a   Sakane, Kazuo ^a   Matsumoto, Satoru ^a   Matsumoto, Yoshimi ^a   Tawara, Shuichi ^a  

^a ASTELLAS PHARMA INC   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

7BETA [2 (2 AMINOTHIAZOL 4 YL) 2 (HYDROXYIMINO)ACETAMIDO] 3 [(4 PYRIDYL)METHYLTHIO] 3 CEPHEM 4 CARBOXYLIC ACID; CEPHALOSPORIN DERIVATIVE; FR 86830; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL INFECTION; DRUG ABSORPTION; DRUG DESIGN; DRUG SYNTHESIS; GRAM NEGATIVE BACTERIUM; MINIMUM INHIBITORY CONCENTRATION; MOUSE; NONHUMAN; RAT; STAPHYLOCOCCUS AUREUS; STRUCTURE ACTIVITY RELATION;

ADMINISTRATION, ORAL; ANIMALS; CEPHALOSPORINS; GRAM-NEGATIVE BACTERIA; GRAM-POSITIVE BACTERIA; MICROBIAL SENSITIVITY TESTS; RATS; STRUCTURE-ACTIVITY RELATIONSHIP;

ANIMALIA; BACTERIA (MICROORGANISMS); NEGIBACTERIA; STAPHYLOCOCCUS AUREUS;

EID: 0034091272     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(00)00021-3     Document Type: Article

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