메뉴 건너뛰기




Volumn 14, Issue 4, 2000, Pages 712-715

Ex vivo assessment of drug response by differential staining cytotoxicity (DiSC) assay suggests a biological basis for equality of chemotherapy irrespective of age for patients with chronic lymphocytic leukaemia

Author keywords

Age; Cellular sensitivity; Chronic lymphocytic leukaemia; Cytotoxic; DiSC assay

Indexed keywords

ANTILEUKEMIC AGENT; CHLORAMBUCIL; CLADRIBINE; CYCLOPHOSPHAMIDE; DOXORUBICIN; EPIRUBICIN; FLUDARABINE; MAFOSFAMIDE; METHYLPREDNISOLONE; PENTOSTATIN; PREDNISOLONE; VINCRISTINE;

EID: 0034091153     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.leu.2401727     Document Type: Article
Times cited : (12)

References (28)
  • 2
    • 0029154446 scopus 로고
    • Corticosteroid resistance is increased in lymphoblasts from adults compared with children: Preliminary results of in vitro drug sensitivity study in adults with acute lymphoblastic leukaemia
    • Maung ZT, Reid MM, Matheson E, Taylor PR, Proctor SJ, Hall AG. Corticosteroid resistance is increased in lymphoblasts from adults compared with children: preliminary results of in vitro drug sensitivity study in adults with acute lymphoblastic leukaemia. Br J Haematol 1995; 91: 93-100.
    • (1995) Br J Haematol , vol.91 , pp. 93-100
    • Maung, Z.T.1    Reid, M.M.2    Matheson, E.3    Taylor, P.R.4    Proctor, S.J.5    Hall, A.G.6
  • 3
    • 0031717981 scopus 로고    scopus 로고
    • Relation between age, immunophenotype and in vitro drug resistance in 395 children with acute lymphoblastic leukemia - Implications for treatment of infants
    • Pieters R, den Boer ML, Durian M, Janka G, Schmiegelow K, Kaspers GJ, van Wering ER, Veerman AJ. Relation between age, immunophenotype and in vitro drug resistance in 395 children with acute lymphoblastic leukemia - implications for treatment of infants. Leukemia 1998; 12: 1344-1348.
    • (1998) Leukemia , vol.12 , pp. 1344-1348
    • Pieters, R.1    Den Boer, M.L.2    Durian, M.3    Janka, G.4    Schmiegelow, K.5    Kaspers, G.J.6    Van Wering, E.R.7    Veerman, A.J.8
  • 4
    • 0031005627 scopus 로고    scopus 로고
    • Acute myeloid leukemia in the elderly: Assessment of multidrug resistance (MDR1) and cytogenetics distinguishes biologic subgroups with remarkably distinct responses to standard chemotherapy. A southwest oncology group study
    • Leith CP, Kopecky KJ, Godwin J, McConnell T, Slovak ML, Chen IM, Head DR, Appelbaum FR, Willman CL. Acute myeloid leukemia in the elderly: assessment of multidrug resistance (MDR1) and cytogenetics distinguishes biologic subgroups with remarkably distinct responses to standard chemotherapy. A Southwest Oncology Group study. Blood 1997; 89: 3323-3329.
    • (1997) Blood , vol.89 , pp. 3323-3329
    • Leith, C.P.1    Kopecky, K.J.2    Godwin, J.3    McConnell, T.4    Slovak, M.L.5    Chen, I.M.6    Head, D.R.7    Appelbaum, F.R.8    Willman, C.L.9
  • 5
    • 0027409765 scopus 로고
    • High-frequency representation of a single VH gene in the expressed human B cell repertoire
    • Stewart AK, Huang C, Stollar BD, Schwartz RS. High-frequency representation of a single VH gene in the expressed human B cell repertoire. J Exp Med 1993; 177: 409-418.
    • (1993) J Exp Med , vol.177 , pp. 409-418
    • Stewart, A.K.1    Huang, C.2    Stollar, B.D.3    Schwartz, R.S.4
  • 6
    • 0028822481 scopus 로고
    • Chronic lymphocytic leukemia
    • Rozman C, Montserrat E. Chronic lymphocytic leukemia. New Engl J Med 1995; 333: 1052-1057.
    • (1995) New Engl J Med , vol.333 , pp. 1052-1057
    • Rozman, C.1    Montserrat, E.2
  • 8
    • 0032838007 scopus 로고    scopus 로고
    • Prognosis for fludarabine therapy of chronic lymphocytic leukaemia based on ex vivo drug response by DiSC assay
    • Bosanquet AG, Johnson SA, Richards SM. Prognosis for fludarabine therapy of chronic lymphocytic leukaemia based on ex vivo drug response by DiSC assay. Br J Haematol 1999; 106: 71-77.
    • (1999) Br J Haematol , vol.106 , pp. 71-77
    • Bosanquet, A.G.1    Johnson, S.A.2    Richards, S.M.3
  • 9
    • 0032860502 scopus 로고    scopus 로고
    • Response to cladribine in previously treated patients with chronic lymphocytic leukaemia identified by ex vivo assessment of drug sensitivity by DiSC assay
    • Bosanquet AG, Copplestone JA, Johnson SA, Smith AG, Povey SJ, Orchard JA, Oscier DG. Response to cladribine in previously treated patients with chronic lymphocytic leukaemia identified by ex vivo assessment of drug sensitivity by DiSC assay. Br J Haematol 1999; 106: 474-476.
    • (1999) Br J Haematol , vol.106 , pp. 474-476
    • Bosanquet, A.G.1    Copplestone, J.A.2    Johnson, S.A.3    Smith, A.G.4    Povey, S.J.5    Orchard, J.A.6    Oscier, D.G.7
  • 10
    • 0028274114 scopus 로고
    • Short-term in vitro drug sensitivity tests for cancer chemotherapy. A summary of correlations of test result with both patient response and survival
    • Bosanquet AG. Short-term in vitro drug sensitivity tests for cancer chemotherapy. A summary of correlations of test result with both patient response and survival. Forum Trends Exp Clin Med 1994; 4: 179-195.
    • (1994) Forum Trends Exp Clin Med , vol.4 , pp. 179-195
    • Bosanquet, A.G.1
  • 11
    • 0029963932 scopus 로고    scopus 로고
    • Enhanced ex vivo drug sensitivity testing of chronic: Lymphocytic leukemia using refined DiSC assay methodology
    • Bosanquet AG, Bell PB. Enhanced ex vivo drug sensitivity testing of chronic: lymphocytic leukemia using refined DiSC assay methodology. Leukemia Res 1996; 20: 143-153.
    • (1996) Leukemia Res , vol.20 , pp. 143-153
    • Bosanquet, A.G.1    Bell, P.B.2
  • 12
    • 0036007546 scopus 로고    scopus 로고
    • Parameters affecting the ex vivo cytotoxic drug sensitivity of human haematopoietic cells
    • in press
    • Bosanquet AG, Burlton AR, Bell PB. Parameters affecting the ex vivo cytotoxic drug sensitivity of human haematopoietic cells. J Exp Ther Oncol (in press).
    • J Exp Ther Oncol
    • Bosanquet, A.G.1    Burlton, A.R.2    Bell, P.B.3
  • 13
    • 0029809147 scopus 로고    scopus 로고
    • Are the elderly receiving appropriate treatment for cancer?
    • Fentiman IA. Are the elderly receiving appropriate treatment for cancer? Ann Oncol 1996; 7: 657-658.
    • (1996) Ann Oncol , vol.7 , pp. 657-658
    • Fentiman, I.A.1
  • 14
    • 0031785723 scopus 로고    scopus 로고
    • Recent developments in the pharmacology of anticancer drugs in the elderly
    • Lichtman SM. Recent developments in the pharmacology of anticancer drugs in the elderly. Curr Opin Oncol 1998; 10: 572-579.
    • (1998) Curr Opin Oncol , vol.10 , pp. 572-579
    • Lichtman, S.M.1
  • 15
    • 0030325192 scopus 로고    scopus 로고
    • Individual variation and age dependency in the radiosensitivity of peripheral blood T-lymphocytes from normal donors
    • Mei N, Imada H, Nomoto S, Kunugita N, Norimura T. Individual variation and age dependency in the radiosensitivity of peripheral blood T-lymphocytes from normal donors. J Radiat Res 1996; 37: 235-245.
    • (1996) J Radiat Res , vol.37 , pp. 235-245
    • Mei, N.1    Imada, H.2    Nomoto, S.3    Kunugita, N.4    Norimura, T.5
  • 16
    • 0025350542 scopus 로고
    • Molecular cytogenetics: Rosetta stone for understanding cancer
    • Rowley JD. Molecular cytogenetics: Rosetta stone for understanding cancer. Cancer Res 1990; 50: 3816-3825.
    • (1990) Cancer Res , vol.50 , pp. 3816-3825
    • Rowley, J.D.1
  • 19
    • 0024458031 scopus 로고
    • On the value of intensive remission-induction chemotherapy in elderly patients of 65+ years with acute myeloid leukemia: A randomised phase III study of the European Organization for Research and Treatment of Cancer Leukemia Group
    • Lowenberg B, Zittoun R, Kerkhofs H, Jehn U, Abels J, Debusscher L, Cauchie C, Peetermans M, Solbu G, Suciu S. On the value of intensive remission-induction chemotherapy in elderly patients of 65+ years with acute myeloid leukemia: a randomised phase III study of the European Organization for Research and Treatment of Cancer Leukemia Group. J Clin Oncol 1989; 7: 1268-1274.
    • (1989) J Clin Oncol , vol.7 , pp. 1268-1274
    • Lowenberg, B.1    Zittoun, R.2    Kerkhofs, H.3    Jehn, U.4    Abels, J.5    Debusscher, L.6    Cauchie, C.7    Peetermans, M.8    Solbu, G.9    Suciu, S.10
  • 20
    • 0026038974 scopus 로고
    • B-cell chronic lymphocytic leukaemia: Present status and future directions
    • Dighiero G, Travade P, Chevret S, Fenaux P, Chastang C, Binet JL. B-cell chronic lymphocytic leukaemia: present status and future directions. Blood 1991; 78: 1901-1914.
    • (1991) Blood , vol.78 , pp. 1901-1914
    • Dighiero, G.1    Travade, P.2    Chevret, S.3    Fenaux, P.4    Chastang, C.5    Binet, J.L.6
  • 21
    • 0028959982 scopus 로고
    • Chronic lymphocytic leukemia: Present status
    • Montserrat E, Rozman C. Chronic lymphocytic leukemia: present status. Ann Oncol 1995; 6: 219-235.
    • (1995) Ann Oncol , vol.6 , pp. 219-235
    • Montserrat, E.1    Rozman, C.2
  • 22
    • 15844368449 scopus 로고    scopus 로고
    • Multicentre prospective randomised trial of fludarabine versus cyclophosphamide, doxorubicin, and prednisone (CAP) for treatment of advanced-stage chronic lymphocytic leukaemia
    • The French Cooperative Group on CLL, Johnson S, Smith AG, Löffler H, Ösby, E, Juliusson G, Emmerich B, Wyld PJ, Hiddemann W. Multicentre prospective randomised trial of fludarabine versus cyclophosphamide, doxorubicin, and prednisone (CAP) for treatment of advanced-stage chronic lymphocytic leukaemia. Lancet 1996; 347: 1432-1438.
    • (1996) Lancet , vol.347 , pp. 1432-1438
    • Johnson, S.1    Smith, A.G.2    Löffler, H.3    Ösby, E.4    Juliusson, G.5    Emmerich, B.6    Wyld, P.J.7    Hiddemann, W.8
  • 23
    • 0025981930 scopus 로고
    • Correlations between therapeutic response of leukaemias and in vitro drug sensitivity assay
    • Bosanquet AG. Correlations between therapeutic response of leukaemias and in vitro drug sensitivity assay. Lancet 1991; 337: 711-714.
    • (1991) Lancet , vol.337 , pp. 711-714
    • Bosanquet, A.G.1
  • 27
    • 0028128964 scopus 로고
    • Clinical aspects of cancer in the elderly. Treatment decisions, treatment choices and follow-up
    • McKenna RJ. Clinical aspects of cancer in the elderly. Treatment decisions, treatment choices and follow-up. Cancer 1994; 74: 2107-2117.
    • (1994) Cancer , vol.74 , pp. 2107-2117
    • McKenna, R.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.