Eczematous plaques related to unfractionated and low-molecular-weight heparins: Cross-reaction with danaparoid but not with desirudin

Contact Dermatitis

Volumn 42, Issue 5, 2000, Pages 295-296

  Martin, L ^a   Machet, L ^a   Gironet, N ^a   Pouplard, C ^a   Gruel, Y ^a   Vaillant, L ^a  

^a SERVICE DE DERMATOLOGIE   (France)

Author keywords

Adverse drug reactions; Delayed hypersensitivity; Heparin; Heparinoids; Low molecular weight heparin; Medicaments; Recombinant hirudins; Tolerance

Indexed keywords

DALTEPARIN; DANAPAROID; DESULFATOHIRUDIN; ENOXAPARIN; HEPARIN CALCIUM; HEPARIN DERIVATIVE; HEPARINOID; LOW MOLECULAR WEIGHT HEPARIN; NADROPARIN; RECOMBINANT HIRUDIN; TINZAPARIN;

ARTICLE; CASE REPORT; DRUG CROSS REACTIVITY; DRUG ERUPTION; ECZEMA; ERYTHEMA; FEMALE; HUMAN; INTRACUTANEOUS TEST; PATCH TEST; PROVOCATION TEST; SKIN TEST;

ANTICOAGULANTS; CHONDROITIN SULFATES; CROSS REACTIONS; DERMATAN SULFATE; DRUG COMBINATIONS; DRUG HYPERSENSITIVITY; FEMALE; HEPARIN, LOW-MOLECULAR-WEIGHT; HEPARINOIDS; HEPARITIN SULFATE; HIRUDINS; HUMANS; HYPERSENSITIVITY, DELAYED; RECOMBINANT PROTEINS; SKIN TESTS;

EID: 0034090739     PISSN: 01051873     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (6)

1. 1. Wütschert R, Piletta P, Bounameaux H. Adverse skin reactions to low molecular weight heparins. Drug Saf 1999: 20: 515-525.
2. 2. Wilde M I, Markham A. Danaparoid. A review of its pharmacology and clinical use in the management of heparin-induced thrombocytopenia. Drugs 1997: 54: 903-924.
3. 3. Sivakumaran M, Ghosh K, Munks R et al. Delayed cutaneous reaction to unfractionated heparin, low molecular weight heparin and heparinoid. Br J Haematol 1994: 86: 893-894.
4. 4. Koch P, Hindi S, Landwehr D. Delayed allergic skin reactions due to subcutaneous heparin-calcium, enoxaparin-sodium, pentosan polysulfate and acute skin lesions from systemic sodium-heparin. Contact Dermatitis 1996: 34: 156-158.
5. 5. Boehncke W H, Weber L, Gall H. Tolerance to intravenous administration of heparin and heparinoid in a patient with delayed-type hypersensitivity to heparins and heparinoids. Contact Dermatitis 1996: 35: 73-75.
6. 6. Hunzelmann N, Gold H, Scharffetter-Kochanek K. Concomitant sensitization to high and low molecular weight heparins, heparinoid and pentosanpolysulfate. Contact Dermatitis 1998: 39: 88-89.