V(β)8+ T cells protect from demyelinating disease in a viral model of multiple sclerosis

International Immunology

Volumn 12, Issue 3, 2000, Pages 271-280

  Drescher, Kristen M ^a,c   Johnston, Sean L ^a   Hogancamp, William ^a   Nabozny, Gerald H ^a   David, Chella S ^a   Rimm, Ilonna J ^b   Wettstein, Peter J ^a   Rodriguez, Moses ^a  

^a MAYO CLINIC   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c CREIGHTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Demyelination; Theiler's murine encephalomyelitis virus; Theiler's virus

Indexed keywords

RECEPTOR ANTIBODY; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; DEMYELINATION; GENE SEGREGATION; GENETIC SUSCEPTIBILITY; MOUSE; MULTIPLE SCLEROSIS; MURINE ENCEPHALOMYELITIS VIRUS; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE RECEPTOR GENE; T LYMPHOCYTE SUBPOPULATION; TRANSGENIC MOUSE; VIRUS INFECTION;

EID: 0034090714     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/12.3.271     Document Type: Article

References (54)

1. Lipton, H. L. and Dal Canto, M. C. 1979. Susceptibility of inbred mice to chronic central nervous system infection by Theiler's murine encephalomyelitis virus. Infect. Immun. 26:369.
2. b gene become resistant to persistent infection by Theiler's virus. J. Virol. 68:4049.
3. Rodriguez, M. and David, C. S. 1985. Demyelination induced by Theiler's virus: influence of the H-2 haplotype. J. Immunol. 135:2145.
4. Rodriguez, M., Leibowitz, J. and David, C. S. 1986. Susceptibility to Theiler's virus-induced demyelination: mapping of the gene within the H-2D region. J. Exp. Med. 163:620.
5. d transgene suppresses Theiler's virus-induced demyelination in susceptible strains of mice. J. Neurovirol. 1:111.
6. Melvold, R. W., Jokinen, D. M., Miller, S. D., Dal Canto, M. C. and Lipton, H. L. 1990. Identification of a locus on mouse chromosome 3 involved in differential susceptibility to Theiler's murine encephalomyelitis virus-induced demyelinating disease. J. Virol. 64:686.
7. Melvold, R. W., Jokinen, D. M., Knobler, R. L. and Lipton, H. L. 1987. Variations in genetic control of susceptibility to Theiler's murine encephalomyelitis virus (TMEV)-induced demyelinating disease. I. Differences between susceptible SJL/J and resistant BALB/c strains map near the T cell beta-chain constant gene on chromosome 6. J. Immunol. 138:1429.
8. Bureau, J. F., Montagutelli, X., Bihl, F., Lefebvre, S., Guenet, J. L. and Brahic, M. 1993. Mapping loci influencing the persistence of Theiler's virus in the murine central nervous system. Nat. Genet. 5:87.
9. Bureau, J. F., Drescher, K. M., Pease, L. R., Vikoren, T., Delcroix, M., Zoecklein, L., Brahic, M. and Rodriguez, M. 1998. Chromosome 14 contains determinants that regulate susceptibility to Theiler's virus-induced demyelination in the mouse. Genetics 148:1941.
10. Yamada, M., Zurbriggen, A. and Fujinami, R. S. 1991. Pathogenesis of Theiler's murine encephalomyelitis virus. Adv. Virus Res. 39:291.
11. Rodriguez, M., Lafuse, W., Leibowitz, J. and David, C. S. 1986. Partial suppression of Theiler's virus-induced demyelination in vivo by administration of monoclonal antibodies to immune response gene products (Ia antigens). Neurol. 36:964.
12. Rodriguez, M. and Sriram, S. 1988. Successful therapy of TMEV-induced demyelination (DA strain) with monoclonal anti-lyt2. 2 antibody. J. Immunol. 140:2950.
13. Rodriguez, M., Patick, A. K. and Pease, L. R. 1990. Abrogation of resistance to Theiler's virus-induced demyelination in C57BL mice by total body irradiation. J. Neuroimmunol. 26:189.
14. Rivera-Quinones, C., McGavern, D., Schmelzer, J. D., Hunter, S. F., Low, P. A. and Rodriguez, M. 1998. Absence of neurological deficits following extensive demyelination in a class I-deficient murine model of multiple sclerosis. Nat. Med. 4:187.
15. 2-microglobulin-deficient mice. J. Virol. 67:589.
16. Njenga, M. K., Pavelko, K. D., Baisch, J., Lin, X., David, C. S., Leibowitz, J. and Rodriguez, M. 1996. Theiler's virus persistence and demyelination in major histocompatibility complex class II-deficient mice. J. Virol. 70:1729.
17. Fiette, L., Brahic, M. and Pena-Rossi, C. 1996. Infection of class-II deficient mice by the DA strain of Theiler's virus. J. Virol. 70:4811.
18. Rodriguez, M., Patick, A. K., Pease, L. R. and David, C. S. 1992. Role of T cell receptor V beta genes in Theiler's virus-induced demyelination of mice. J. Immunol. 148:921.
19. Lipton, H. L. 1975. Theiler's virus infection in mice: an unusual biphasic disease process leading to demyelination. Infect. Immun. 11:1147.
20. Rodriguez, M., Pavelko, K. D., Njenga, M. K., Logan, W. C. and Wettstein, P. J. 1996. The balance between persistent virus infection and immune cells determines demyelination. J. Immunol. 157:5699.
21. Lin, X., Sato, H., Patick, A. K., Pease, L. R., Roos, R. P. and Rodriguez, M. 1998. Molecular characterization of a nondemyelinating variant of Daniel's strain of Theiler's virus isolated from a persistently infected glioma cell line. J. Virol. 72:1262.
22. β genes on the Theiler's virus model of multiple sclerosis. Autoimmunity 19:221.
23. Fenton, R. G., Marrack, P., Kappler, J. W., Kanagawa, O. and Seidman, J. G. 1988. Isotypic exclusion of gamma-delta T cell receptors in transgenic mice bearing a rearranged b-chain gene. Science 241:1049.
24. Kappler, J. W., Staerz, U., White, J. and Marrack, P. C. 1988. Self-tolerance eliminates T cells specific for MIs-modified products of the major histocompatibility complex. Nature 322:35.
25. dml mice. Ann. Neurol. 33:208.
26. Rodriguez, M., Nickerson, C., Patick, A. K. and David, C. S. 1991. Expression of human HLA-B27 transgene alters susceptibility to murine Theiler's virus-induced demyelination. J. Immunol. 146:2596.
27. Pierce, M. L. and Rodriguez, M. 1989. Erichrome stain for myelin on osmicated tissue embedded in glycol methacrylate plastic. J. Histotech. 12:35.
28. Rodriguez, M., Leibowitz, J. L. and Lampert, P. W. 1983. Persistent infection of oligodendrocytes in Theiler's virus-induced encephalomyelitis. Ann. Neurol. 13:426.
29. Johnston, S. L. and Wettstein, P. J. 1997. T cell receptor diversity in CTLs specific for the CTT-1 and CTT-2 minor histocompatibility antigens. J. Immunol. 159:5233.
30. Lin, X., Thiemann, R., Pease, L. R. and Rodriguez, M. 1995. VP1 and VP2 capsid proteins of Theiler's virus are targets of H-2D-restricted cytotoxic lymphocytes in the central nervous system of B10 mice. Virology 214:91.
31. b mice deficient in β 2-microglobulin. J. Immunol. 151:266.
32. Rodriguez, M., Prayoonwiwat, N., Zhou, P. and David, C. 1993. Expression of T cell receptor V beta transcripts in central nervous system of mice susceptible and resistant to Theiler's virus-induced demyelination. J. Neuroimmunol. 47:95.
33. Puisieux, I., Even, J., Pannetier, C., Jotereau, F., Favrot, M. and Kourilsky, P. 1994. Oligoclonality of tumor-infiltrating lymphocytes from human melanomas. J. Immunol. 153:2807.
34. Caignard, A., Dietrich, P., Morand, V., Lim, A., Pannetier, C., Leridant, A. M., Hercend, T., Even, J., Kourilsky, P. and Triebel, F. 1994. Evidence for T-cell clonal expansion in a patient with squamous cell carcinoma of the head and neck. Cancer Res. 54:1292.
35. Dietrich, P. Y., Caignard, A., Lim, A., Chung, V., Pico, J. L., Pannetier, C., Kourilsky, P., Hercend, T., Even, J. and Triebel, F. 1994. In vivo T-cell clonal amplification at time of acute graft-versus-host disease. Blood 84:2815.
36. Musette, P., Bureau, J. F., Gachelin, G., Kourilsky, P. and Brahic, M. 1995. T lymphocyte repertoire in Theiler's virus encephalomyelitis: the nonspecific infiltration of the central nervous system of infected SJL/J mice is associated with a selective local T cell expansion. Eur. J. Immunol. 25:1589.
37. Nabozny, G. H., Rimm, I. J., Griffiths, M. M., Luthra, H. S. and David, C. S. 1995. Expression of an ovalbumin-specific V beta 8.2 TCR transgene inhibits collagen arthritis in B10.Q mice. Int. Immunol. 7:1279.
38. Lomo, L. C., Motte, R. W., Giraldo, A. A., Nabozny, G. H., David, C. S., Rimm, I. J. and Kong, Y. M. 1996. V beta 8.2 transgene expression interferes with development of experimental autoimmune thyroiditis in CBA k/q but not k/k mice. Cell. Immunol. 168:297.
39. Rimm, I. J., Krenger, W., Beland, J. L., Geller, M. C., DiSavino, E., Yui, K., Katsumata, M. and Ferrara, J. L. 1996. TCR-beta transgenic mice fail to mediate GVHR due to defects of allorecognition and subsequent IL-2 generation. Bone Marrow Transplant. 17:835.
40. Imrich, H., Kugler, C., Torres-Nagel, N., Dorries, R. and Hunig, T. 1995. Prevention and treatment of Lewis rat experimental allergic encephalomyelitis with a monoclonal antibody to the T cell receptor V beta 8.2 segment. Eur. J. Immunol. 25:1960.
41. Dethlefs, S., Escriou, N., Brahic, M., van der Werf, S. and Larsson-Sciard, E. L. 1997. Theiler's virus and mengo virus induce cross-reactive cytotoxic T lymphocytes restricted to the same immunodominant VP2 epitope in C57BL/6 mice. J. Virol. 71:5361.
42. b molecules complexed with a viral VP2 peptide lacking a consensus anchor residue. J. Virol. 71:5244.
43. Arrunategui-Correa, V., Dutt, J. E. and Foster, C. S. 1997. Analysis of T cell receptor V beta gene expression in B cell deficient mice after experimental herpes simplex keratitis. Acta Virol. 41:145.
44. b-restricted response to an influenza A virus neucleoprotein epitope. J. Immunol. 151:2658.
45. Chluba, J., Steeg, C., Becker, A., Wekerle, H. and Epplen, J. T. 1989. T cell receptor beta chain usage in myelin basic protein-specific T lymphocytes. Eur. J. Immunol. 19:279.
46. h2 T cells. Trans Am. Ophthal. Soc. 91:325.
47. + T lymphocytes in experimental autoimmune uveoretinitis induced with two different retinal antigens. J. Immunol. 151:1627.
48. Gregorian, S. K., Clark, L., Heber-Katz, E., Amento, E. P. and Rostami, A. 1993. Induction of peripheral tolerance with peptide-specific anergy in experimental autoimmune neuritis. Cell Immunol. 150:298.
49. + T cells in demyelinating disease following Theiler's virus infection: a model for multiple sclerosis. J. Neurovirol. 3:S43.
50. Drescher, K. M., Murray, P. D., David, C. S., Pease, L. R. and Rodriguez, M. 1999. CNS cell populations are protected from virus-induced pathology by distinct arms of the immune system. Brain Pathol. 9:21.
51. Fiette, L., Aubert, C., Muller, U., Huang, S., Auget, M., Brahic, M. and Bureau, J. F. 1995 Theiler's virus infection of 129 Sv mice that lack the interferon α/β or interferon γ receptors. J. Exp. Med. 181:2069.
52. Patick, A. K., Pease, L. R., David, C. S. and Rodriguez, M. 1990. Major histocompatibility complex-conferred resistance to Theiler's virus-induced demyelinating disease is inherited as a dominant trait in B10 congenic mice. J. Virol. 64:5570.
53. Miller, S. D., Vanderlugt, C. L., Smith Begolka, W., Pao, W., Yauch, R. L., Neville, K. L., Katz-Levy, Y., Carrizosa, A. and Kim, B. S. 1997. Persistent infection with Theiler's virus leads to CNS autoimmunity via epitope spreading. Nat. Med. 3:1133.
54. Kucheroo, V. K., Collins, M., al-Sabbagh, A., Sobel, R. A., Whitters, M. J., Zamvil, S. S., Dorf, M. E., Hafler, D. A., Seidman, J. G. and Weiner, H. L. 1994. T cell receptor (TCR) usage determines disease susceptibility in experimental autoimmune encephalomyelitis: studies with TCR V beta 8.2 transgenic mice. J. Exp. Med. 179:1659.