Effects of aging on neurogenic vasodilator responses evoked by transcutaneous electrical nerve stimulation: Relevance to wound healing

Journals of Gerontology - Series A Biological Sciences and Medical Sciences

Volumn 55, Issue 6, 2000, Pages

  Khalil, Zeinab ^a   Merhi, Merhi ^b  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOPPLER FLOWMETER; ELECTROSTIMULATION THERAPY; NERVE STIMULATION; NONHUMAN; PRIORITY JOURNAL; RAT; SENSORY NERVE; VASODILATATION; WOUND HEALING;

ANIMALIA;

EID: 0034090074     PISSN: 10795006     EISSN: None     Source Type: Journal    
DOI: 10.1093/gerona/55.6.B257     Document Type: Article

References (46)

1. Richards AM, Mitsou J, Floyd DC, Terenghi G, McGrouther DA. Neural innervation and healing. Lancet. 1997;350:339-340.
2. Kjartansson J, Dalsgaard CJ. Calcitonin gene-related peptide increases survival of a musculocutaneous critical flap in the rat. Eur J Pharmacol. 1987;142:355-358.
3. Pincelli C, Fantini F, Romualdi P, et al. Substance P is diminished and vasoactive intestinal peptide is augmented in psoriatic lesions and these peptides exert disparate effects on the proliferation of cultured human keratinocytes. J Invest Dermatol. 1992;98:421-427.
4. Benrath J, Zimmermann M, Gillardon F. Substance P and nitric oxide mediate wound healing of ultraviolet photodamaged rat skin: evidence for an effect of nitric oxide on keratinocyte proliferation. Neurosci Lett. 1995;200:17-20.
5. Khalil Z, Helme RD. Sensory peptides as neuromodulators of wound healing in aged rats. J Gerontol Biol Sci. 1996;51A:B354-B361.
6. Nilsson J, Von Euler AM, Dalsgaard CJ. Stimulation of connective tissue cell growth by substance P and substance K. Nature. 1985;315:61-63.
7. Haegerstrand A, Dalsgaard CJ, Jonzon B, Larsson O, Nilsson J. Calcitonin gene-related peptide stimulates proliferation of human endothelial cells. Proc Natl Acad Sci USA. 1990;87:3299-3303.
8. Ziche M, Morbidelli L, Pacini M, Geppetti P, Alessandri G, Maggi CA. Substance P stimulates neovascularization in vivo and proliferation of cultured endothelial cells. Microvasc Res. 1990;40:264-278.
9. Kjartansson J, Lundeberg T, Samuelson UE, Dalsgaard CJ. Transcutaneous electrical nerve stimulation (TENS) increases survival of ischaemic musculocutaneous flaps. Acta Physiol Scand. 1988;13:95-99.
10. Jansen G, Lundeberg T, Kjartansson J, Samuelson UE. Acupuncture and sensory neuropeptides increase cutaneous blood flow in rats. Neurosci Lett. 1989;97:305-309.
11. Knight KR, Kawabata H, Coe SA, Martin TJ, Angus JA, O'Brien BM. The salvage of rabbit ischaemic epigastric free flaps using the vasodilator calcitonin gene-related peptide. Br J Plast Surg. 1990;43:447-451.
12. Jernbeck J, Dalsgaard CJ. Calcitonin gene-related peptide treatment of flaps with compromised circulation in humans. Plast Reconstr Surg. 1993;91:236-244.
13. Khalil Z, Ralevic V, Bassirat M, Dusting GJ, Helme RD. Effect of ageing on sensory nerve function in rat skin. Brain Res. 1994;641: 265-272.
14. Cohen BJ, Danon D, Roth GS. Wound repair in mice as influenced by age and antimacrophage serum. J Gerontol. 1987;42:295-301.
15. Eaglstein W. Wound healing and ageing. Clin Geriat Med. 1989;5: 183-188.
16. Jones PL, Millman A. Wound healing and the aged patient. Nursing Clin N Am. 1990;25:263-277.
17. Roth GS, Kowatch MA, Hengemihle J, et al. Effect of age and caloric restriction on cutaneous wound closure in rats and monkeys. J Gerontol Biol Sci. 1997;52A:B98-B102.
18. Kloth LC, McCulloch JM. Promotion of wound healing with electrical stimulation. Adv Wound Care. 1996;9(5):42-45.
19. Alvarez OM, Mertz PM, Smerbeck RV, Eaglstein WH. The healing of superficial skin wounds is stimulated by external electrical current. J Invest Dermatol. 1983;81:144-148.
20. Brown M, McDonnell MK, Menton DN. Polarity effects on wound healing using electric stimulation in rabbits. Arch Phys Med Rehabil. 1989;70:624-627.
21. Cruz NI, Bayron FE, Suarez AJ. Accelerated healing of full-thickness burns by the use of high-voltage pulsed galvanic stimulation in the pig. Ann Plast Surg. 1989;23:49-55.
22. Stromberg BV. Effects of electrical currents on wound contraction. Ann Plast Surg. 1988;21:121-123.
23. Lundeberg T, Kjartansson J, Samuelsson U. Effect of electrical nerve stimulation on healing of ischaemic skin flaps. Lancet. 1988;ii:712-714.
24. Feedar JA, Kloth LC, Gentzkow GD. Chronic dermal ulcer healing enhanced with monophasic pulsed electrical stimulation. Phys Ther. 1991;71:639-649.
25. Lundeberg TC, Eriksson SV, Malm M. Electrical nerve stimulation improves healing of diabetic ulcers. Ann Plast Surg. 1992;29:328-331.
26. Baker LL, Chambers R, Demuth SK, Villar F. Effects of electrical stimulation on wound healing in patients with diabetic ulcers. Diabetes Care. 1997;20:405-412.
27. Merhi M, Helme RD, Khalil Z. Age-related changes in sympathetic modulation of sensory nerve activity in rat skin. Inflamm Res. 1998; 47:239-244.
28. Ganong WF. Excitable tissue: nerve. In: Ganong WF, ed. Review of Medical Physiology. 16th ed., Englewood Cliffs, NJ: Prentice Hall; 1993.
29. Willette RN, Hieble P, Sauermelch CF. Sympathetic regulation of cutaneous circulation in the rat. J Auton Nerv Syst. 1991;32:135-144.
30. Kurvers HA, Tangelder GJ, De Mey JG, et al. Skin blood flow abnormalities in a rat model of neuropathic pain: result of decreased sympathetic vasoconstrictor outflow? J Auton Nerv Syst. 1997;63:19-29.
31. Pinter E, Helyes Z, Petho G, Szolcsanyi J. Noradrenergic and peptidergic sympathetic regulation of cutaneous microcirculation in the rat. Eur J Pharmacol. 1997;325:57-64.
32. Matran R, Martling CR, Lundberg JM. Inhibition of cholinergic and non-adrenergic, non-cholinergic bronchoconstriction in the guinea pig mediated by neuropeptide Y and alpha 2-adrenoceptors and opiate receptors. Eur J Pharmacol. 1989;163:15-23.
33. De Luca A, Li CG, Rand MJ, Reid JJ, Thaina P, Wong-Dusting HK. Effects of ω-conotoxin GVIA on autonomic neuroeffector transmission in various tissues. Br J Pharmacol. 1990;101:437-447.
34. Kawasaki H, Nuki C, Saito A, Takasaki K. Adrenergic modulation of CGRP-containing nerve-mediated vasodilatation in the rat mesenteric resistance vessels. Brain Res. 1990;506:287-290.
35. 2-receptors in rabbit iris. Naunyn Schimiedeberg's Arch Pharmacol. 1993;347:394-401.
36. Lou YP. Regulation of neuropeptide release from pulmonary capsaicin-sensitive afferents in relation to bronchoconstriction. Acta Physiol Scand Suppl. 1993;612:1-88.
37. Nicholas AP, Pieribone V, Hokfelt T. Distributions of mRNAs for alpha-2 adrenergic receptor subtypes in rat brain: an in situ hybridization study. J Comp Neurol. 1993;328:575-594.
38. Jancso G, Kiraly E, Jansco-Gabor A. Pharmacologically induced selective degeneration of chemosensitive primary sensory neurones. Nature. 1977;270:741-743
39. Lembeck F, Holzer P, Substance P as a neurogenic mediator of antidromic vasodilatation and neurogenic plasma extravasation. Naunyn Schmiedeberg's Arch Pharmacol. 1979;310:175-183.
40. Lynn B. Capsaicin: actions on nociceptive C-fibres and therapeutic potential. [Review]. Pain. 1990;41:61-69.
41. Bassirat M, Helme RD, Khalil Z. Effect of chronic sciatic nerve lesion on the neurogenic inflammatory response in intact and acutely injured denervated rat skin, Inflamm Res. 1996;45:380-385.
42. Gersh MR, Wolf SL. Applications of transcutaneous electrical nerve stimulation in the management of patients with pain. State-of-the-art update. Phys Ther. 1985;65:314-336.
43. Scudds RJ, Helewa A, Scudds RA. The effects of transcutaneous electrical nerve stimulation on skin temperature in asymptomatic subjects. Phys Ther. 1995;75:621-628.
44. Lynn B, Shakhanbeh J. Neurogenic inflammation in skin of the rabbit. Agents Actions. 1988;25(3-4):228-230.
45. Torebjork E. Nociceptor activation and pain. Philos Trans R Soc Lond (Biol). 1985;308:227-234.
46. Szolscanyi J, Anton F, Reeh PW, Handwerker HO. Selective excitation by capsaicin of mechano-heat sensitive nociceptors in rat skin. Brain Res. 1988;446:262-268.