Toxicity and blood concentrations of xylazine and its metabolite, 2,6- dimethylaniline, in rats after single or continuous oral administrations

Journal of Toxicological Sciences

Volumn 25, Issue 2, 2000, Pages 105-113

  Yasuhara, Kazuo ^a   Kobayashi, Hiroko ^b   Shimamura, Yuji ^c   Koujitani, Takatoshi ^a   Onodera, Hiroshi ^a   Takagi, Hisayoshi ^a   Hirose, Masao ^a   Mitsumori, Kunitoshi ^a  

^a NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^b Res Inst Japan Plant Protect A   (Japan)

^c INSTITUTE OF ENVIRONMENTAL TOXICOLOGY   (Japan)

Author keywords

2,6 Dimethylaniline; Nasal cavity; Plasma concentration; Pulmonary edema; Thyroid gland; Xylazine

Indexed keywords

2,6 DIMETHYLANILINE; UNCLASSIFIED DRUG; XYLAZINE;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHEMICAL CARCINOGENESIS; CONTROLLED STUDY; DRUG BLOOD LEVEL; HISTOPATHOLOGY; HYDROTHORAX; LUNG EDEMA; MALE; MAXIMUM ALLOWABLE CONCENTRATION; MUTAGEN TESTING; NONHUMAN; NOSE CANCER; OLFACTORY EPITHELIUM; RAT; TOXICITY TESTING; TOXICOKINETICS;

EID: 0034089418     PISSN: 03881350     EISSN: 18803989     Source Type: Journal    
DOI: 10.2131/jts.25.105     Document Type: Article

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