A monoclonal antibody raised against human β-factor XIIa which also recognizes α-factor XIIa but not factor XII or complexes of factor XIIa with C1̄ esterase inhibitor

Thrombosis and Haemostasis

Volumn 83, Issue 6, 2000, Pages 874-881

  Esnouf, M Peter ^a   Burgess, Annette I ^a   Dodds, Alister W ^b   Sarphie, Anna F ^a   Miller, George J ^c,d  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b MRC Immunochemistry Unit   (United Kingdom)

^c QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^d MEDICAL RESEARCH COUNCIL   (United Kingdom)

Author keywords

Affinity binding studies; ELISA; Factor XIIa; Monoclonal antibody

Indexed keywords

3,4 DICHLOROISOCOUMARIN; BLOOD CLOTTING FACTOR 12; BLOOD CLOTTING FACTOR 12A; COMPLEMENT COMPONENT C1S INHIBITOR; ENZYME PRECURSOR; MONOCLONAL ANTIBODY; TRITON X 100;

ANTIGEN RECOGNITION; ARTICLE; BINDING AFFINITY; ENZYME LINKED IMMUNOSORBENT ASSAY; GEL FILTRATION; HUMAN; IMMUNOBLOTTING; PRIORITY JOURNAL;

EID: 0034089121     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0037-1613936     Document Type: Article

References (31)

1. Ratnoff OD, Saito H. Interactions among Hageman factor, plasma prekallikrein, high molecular weight kininogen, and plasma thromboplastin antecedent. Proc Natl Acad Sci USA 1979; 76: 958-61.
2. Tans G, Rosing J, Griffin JH. Sulfatide-dependent autoactivation of human blood coagulation Factor XII (Hageman Factor). J Biol Chem 1983; 258: 8215-22.
3. Small EJ, Katzmann JA, Tracy RP, Ratnoff OD, Goldsmith GH, Jr., Everson B. A monoclonal antibody that inhibits activation of human Hageman factor (factor XII). Blood 1985; 65: 202-10.
4. Saito H, Ishihara T, Suzuki H, Watanahe T. Production and characterization of a murine monoclonal antibody against a heavy chain of Hageman factor (factor XII). Blood 1985; 65: 1263-8.
5. Clarke BJ, Cote HC, Cool DE, Clark Lewis I, Saito H, Pixley RA, Colman RW, MacGillivray RT. Mapping of a putative surface-binding site of human coagulation factor XII. J Biol Chem 1989; 264: 11497-502.
6. Pixley RA, Colman RW. A monoclonal antibody recognizing an iscosapeptide sequence in the heavy chain of human factor XII inhibits surface-catalyzed activation. Adv Exp Med Biol 1989; 247a: 473-6.
7. Nuijens JH, Huijbregts CC, Eerenberg Belmer AJ, Meijers JC, Bouma BN, Hack CE. Activation of the contact system of coagulation by a monoclonal antibody directed against a neodeterminant in the heavy chain region of human coagulation factor XII (Hageman factor). J Biol Chem 1989; 264: 12941-9.
8. Ravon DM, Citarella F, Lubbers YT, Pascucci B, Hack CE. Monoclonal antibody F1 binds to the kringle domain of factor XII and induces enhanced susceptibility for cleavage by kallikrein. Blood 1995; 86: 4134-43.
9. Lachmann PJ, Strangeways L, Vyakarnam A, Evan G. Raising antibodies by coupling peptides to PPD and immunizing BCG-sensitized animals. Ciba Found Symp 1986; 119: 25-57.
10. Kohler G, Milstein C. Continuous cultures of fused cells secreting antibody of predefined specificity. Nature 1975; 256: 495-7.
11. Ford RP, Esnouf MP, Burgess AI, Sarphie AF. An enzyme linked immuno-absorbent assay (ELISA) for the measurement of activated factor XII (Hageman factor) in human plasma. J. Immunoassay 1996; 17: 119-31.
12. Fujikawa K, Davie EW. Human factor XII (Hageman factor). Methods Enzymol 1981; 80 Pt C: 198-211.
13. Kohn J, Wilchek M. A new approach (cyano-transfer) for cyanogen bromide activation of Sepharose at neutral pH, which yields activated resins, free of interfering nitrogen derivatives. Biochem Biophys Res Commun 1982; 107: 878-84.
14. Fujikawa K, McMullen BA. Amino acid sequence of human beta-factor XIIa. J Biol Chem 1983; 258: 10924-33.
15. Jameson GW, Roberts DV, Adams RW, Kyle WS, Elmore DT. Determination of the operational molarity of solutions of bovine alpha-chymotrypsin, trypsin, thrombin and factor Xa by spectrofluorimetric titration. Biochem J 1973; 131: 107-17.
16. Sim RB, Reboul A. Preparation and properties of human C1 inhibitor. Methods Enzymol 1981; 80 Pt C: 43-54.
17. Proctor RR, Rapaport SI. The partial thromboplastin time with kaolin:a simple screening test for the first stage plasma clotting deficiencies. Am J Clin Pathol 1961; 35: 212-9.
18. Friguct B, Chaffotte AF, Djavadi Ohaniance L, Goldberg ME. Measurements of the true affinity constant in solution of antigen-antibody complexes by enzyme-linked immunosorbent assay. J Immunol Methods 1985: 77: 305-19.
19. Kam CM, Fujikawa K, Powers JC. Mechanism-based isocoumarin inhibitors for trypsin and blood coagulation serine proteases: new anticoagulants. Biochemistry 1988; 27: 2547-57.
20. Burnette WN. "Western blotting": electrophoretic transfer of proteins from sodium dodecyl sulfate-polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A. Anal Biochem 1981; 112: 195-203.
21. Knecht DA, Dimond RL. Visualization of antigenic proteins on Western blots. Anal Biochem 1984; 136: 180-4.
22. Saito H. The contact phase of blood coagulation. In: Bloom AL, Forbes CD, Thomas DP, Tuddenham EGD, eds. Haemostasis and Thrombosis. 3rd ed. London: Churchill Livingstone, 1994: 289. vol 1.
23. Cool DE, Edgell CJ, Louie GV, Zoller MJ, Brayer GD, MacGillivray RT. Characterization of human blood coagulation factor XII cDNA. Prediction of the primary structure of factor XII and the tertiary structure of beta-factor XIIa. J Biol Chem 1985; 260: 13666-76.
24. Munakata M, Komiyama Y, Mori T, Okuda K, Murakami T, Masuda M, Egawa H, Takahashi H. Evaluation of the factor XIIa assay kit. Rinsho-Byori 1996; 44: 883-8.
25. Pixley RA, Schapira M, Colman RW. The regulation of human factor XIIa by plasma proteinase inhibitors. J Biol Chem 1985; 260: 1723-9.
26. Cardigan RA, Donohoe S, Purdy G, Mackie IJ, Machin SJ. The association of factor VIIa, factor XIIa and beta2-glycoprotein-1 with triglyceride-rich lipoproteins in normolipidaemic subjects. Blood Coagul Fibrinolysis 1998; 9: 323-32.
27. Boisclair MD, Lane DA, Philippou H, Esnouf MP, Sheikh S, Hunt B, Smith KJ. Mechanisms of thrombin generation during surgery and cardiopulmonary bypass. Blood 1993; 82: 3350-7.
28. Coppola R, Cristilli P, Cugno M, Ariens RA, Mari D, Mannucci PM. Measurement of activated factor XII in health and disease. Blood Coagul Fibrinolysis 1996; 7: 530-5.
29. Cugno M, Cicardi M, Bottasso B, Coppola R, Paonessa R, Mannucci PM, Agostini A. Activation of the coagulation cascade in C1-inhibitor deficiencies. Blood 1997; 89: 3213-8.
30. Miller GJ, Esnouf MP, Burgess AI, Cooper JA, Mitchell JP. Risk of Coronary Heart Disease and activation of Factor XII in Middle-Aged Men. ArteriosclerThromb Vasc Biol 1997; 17: 2103-6.
31. Kohler HP, Carter AM, Stickland MH, Grant PJ. Levels of activated FXII in survivors of myocardial infarction-association with circulating risk factors and extent of coronary artery disease. Thromb Haemost 1998; 79: 14-8.