Cancer-associated retinopathy;Karzinomassoziierte retinopathie: Eine ubersicht mit klinischen beispielen

Klinische Monatsblatter fur Augenheilkunde

Volumn 216, Issue 1, 2000, Pages 17-24

  Sobottka, Beate ^a,b   Schlote, Torsten ^a,c   Besch, Dorothea ^a,d   Djelebova, Tzonka ^a,d   Wilhelm, Helmut ^a,d   Zrenner, Eberhart ^a,d  

^a UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

^b Abteilung III Glaskörper und Netzhautchirurgie   (Germany)

^c Abteilung I: Allgemeine Augenheilkunde mit Poliklinik   (Germany)

^d Abteilung II: Pathophysiologie des Sehens und Neuroophthalmologie   (Germany)

Author keywords

Cancer associated retinopathy; Carcinoma of the endometrium; Mamma carcinoma; Paraneoplastic neurological syndromes; Paraneoplastic optic neuropathy; Paraneoplastic syndrome

Indexed keywords

CORTICOSTEROID; PREDNISONE;

BREAST CARCINOMA; CANCER; DIFFERENTIAL DIAGNOSIS; ELECTRORETINOGRAM; ENDOMETRIUM CARCINOMA; HUMAN; LUNG CARCINOMA; OPTIC NERVE DISEASE; PARANEOPLASTIC SYNDROME; PROGNOSIS; PROSTATE CARCINOMA; RETINOPATHY; REVIEW; VISUAL IMPAIRMENT;

AGED; AUTOANTIBODIES; BREAST NEOPLASMS; CALCIUM-BINDING PROTEINS; CARCINOMA; DIAGNOSIS, DIFFERENTIAL; ELECTRORETINOGRAPHY; EYE PROTEINS; FEMALE; HIPPOCALCIN; HUMANS; LIPOPROTEINS; MALE; MIDDLE AGED; NERVE TISSUE PROTEINS; OPTIC NEURITIS; PARANEOPLASTIC SYNDROMES; RECOVERIN; RETINAL DISEASES; UTERINE NEOPLASMS;

EID: 0034089004     PISSN: 00232165     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2000-10511     Document Type: Review

References (68)

1. Adamus G, Guy J, Dchmied JL, et al. Role of Anti-recoverin autoantibodies in cancer-associated retinopathy. Invest Ophthalmol Vis Sci 1993; 34: 2626-2633
2. Aptsiauri N, Jordan BI, Heckenlively J. Anti-recoverin immuno-reactivity in patients with retinal degeneration without systemic malignancy. ARVO abstracts. Invest Ophthalmol Vis Sci 1998; 39(4, Suppl.): S.363
3. Bearse MA, Sutter EE. Imaging localized retinal dysfunction with the multi-focal electroretinogram. Opt Soc Am J A 1996; 13: 634-640
4. Berson EL, Lessell S. Paraneoplastic night blindness with malignant melanoma. Am J Ophthalmol 1988; 106: 307-311
5. Boghen D, Sebag M, Michaud J. Paraneoplastic optic neuritis and encephalomyelitis: report of a case. Arch Neurol 1988; 45: 353-356
6. Boucher MA, Allaire GS. Cancer-associated retinopathy: a clinico-pathological case report. Can J Ophthalmol 1997; 32: 46-49
7. Brink H, Deutmann A, Beex L Unusual retinal pigment epitheliopathy and choroidopathy in carcinomatosis: a rare cae of cancer-associated retinopathy. Graefe's Arch Clin Exp Ophthalmol 1997; 235: 59-61
8. Buchanan TAS, Gardiner TA, Archer DB. An ultrastructural study of retinal photoreceptor degeneration associated with bronchial carcinoma. Am J Ophthalmol 1984; 97: 277-287
9. Campo E, Brunier MN, Merino MJ. Small cell carcinoma of the endometrium with associated ocular paraneoplastic syndrome. Cancer 1992; 69: 2283-2288
10. Christian CL, Elkon KB. Autoantibodies to intracellular proteins. Clinical and biological significance. Am J Med 1986; 80: 53-61
11. Cogan DG, Kuwabara T, Currie J, Kattah J. Paraneoplastische Retinopathie unter dem klinischen Bild einer Zapfendystrophie und Achromatopsie. KHn Monatsbl Augenheilkd 1990; 197: 156-158
12. Crofts JW, Bachynski BN, Odel JG. Visual paraneoplastic syndrome associated with undifferentiated endometrial carcinoma. Can J Ophthalmol 1988; 23: 128-132
13. Dizhoor AM, Ray S, Kumar S, et al. Recoverin: a calcium sensitive activator of retinal rod guaylate cyclase. Science 1991; 251: 915-918
14. Gehrs K, Tiedemann J. Hemeralopia in an older adult. Surv Ophthalmol 1992; 37: 185-189
15. Grunwald GB, Klein R, Simmonds MA, Kornguth SE. Autoimmune basis for visual paraneoplastic syndrome in patients with small cell lung carcinoma. Lancet 1985; 1: 658-661
16. Grunwald GB, Kornguth SE, Towfighi J, et al. Autoimmune basis for visual paraneoplastic syndrome in patients with small cell lung carcinoma: retinal immune deposits and ablation of retinal ganglion cells. Cancer 1987; 60: 780-786
17. Guy JR, Adamus G, Aptsiauri N, et al. Cancer associated retinopathy: a new antibody. Invest Ophthalmol Vis Sci 1993; 100 (Suppl): 116
18. Guy J, Aptsiauri N. IVIg protocol: reversal of carcinoma ssociated retinopathy (CAR) induced blindness with IVIg. Neurology 1997; 48 (Suppl): A329 -A330
19. Hammerstein W, Jurgens H, Gobel U. Retinadegeneration und embryonales Rhabdomyosarkom des Thorax. Fortschr Ophthalmol 1991; 88: 463-465
20. Hararda T, Fukami H, Takeuchi T, et al. Interferone-assoziierte Retinopathie. Klin Monatsbl Augenheilkd 1995; 207: 302-304
21. Heckenlively JR, Oversier JJ, Jordan B, Aptsiauri N. CAR-like syndrome: progressive panretinal degenerations not associated with cancer but with anti-recoverin (and other) anti-retinal antibodies. ARVO abstracts. Invest Ophthalmol Vis Sci 1998; 39 (4, suppl): 5216
22. Henson RA, Russel DS, Wilkinson M. Carcinomatous neuropathy and myopathy: a clinical and pathological study. Brain 1954; 77: 82-121
23. Honorat: J, Antoine JC, Derringto E, et al, Antibodies to a subpopulation of glial cells and a 66kDa developmental protein in patients with paraneoplastic neurological syndromes. J Neurol Neurosurg Psychiatry 1996; 61: 270-278
24. Jacobsen DM, Thirkill CE, Tipping SJ. A clinical triad to diagnose paraneoplastic retinopathy. Ann Neurol 1990; 28: 162-167
25. Jordan BL, Dawson WW, Weeks CL, Tahir R, Hazariwala K, Marsh RD. Anti-retina antibody responses in patients with cancer associated retinal deficit (CARD). ARVO abstracts. Invest Ophthalmol Vis Sci 1999; 40(4,suppl): S153
26. Keltner JL, Roth AM, Chang RS. Photoreceptor degeneration: possible autoimmune disorder. Arch Ophthalmol 1983; 101: 564-569
27. Keltner JL, Thirkill CE, Tyler NK, Roth AM. Management and monitoring of cancer-associated retinopathy. Arch Ophthalmol 1992; 110: 48-53
28. Klingele TG, Burde RM, Rappazzo JA, et al. Paraneoplastic retinopathy. J Clin Neuro Ophthalmol 1984; 4: 239-245
29. Kornguth SE. Neuronal proteins and paraneoplastic syndromes. N Eng J Med 1989; 321: 1607-1608
30. Kornguth SE, Kalinke T, Grunwald GB, et al. Antineurofilament antibodies in the sera of patients with small cell carcinoma of the lung and visual paraneoplastic syndrome. Cancer Res 1986; 46: 2588-2593
31. Kornguth SE, Klein R, Appen R, Choate J. Occurrence of antiretinal ganglion cell antibodies in patiens with small cell carcinoma of the lung. Cancer 1982; 50: 1289-1293
32. Kretschmann U, Rüther K, Usui T, Zrenner E. ERG campimetry using a multi-input Stimulation technique for mapping of retinal function in the central visual field. Ophthalmic Res 1996; 160: 303-311
33. Kretschmann U, Schlote T, Stübiger N, et al. Multifokale Elektro-retinographie bei erworbenen Makulafunktionsstörungen. Klin Monatsbl Augenheilkd 1998; 212: 93-100
34. Kupersmith MJ, Seiple WH, Holopigian K, et al. Maculopathy caused by intra-arterially administered cisplatin and intravenously administered carmustine. Am J Ophthalmol 1992; 113: 435-438
35. Malik S, Furlan AJ, Sweeney PJ, et al. Optic neuropathy a rare paraneoplsatic syndrome. J Clin Neuroophthalmol 1992; 12: 137-141
36. Marmor MF, Zrenner E. Standard for clinical electroretinography (1994 upgrade). Doc Ophthalmol 1995; 89: 199-210
37. Matsui Y, Mehta MC, Katsumi O, et al. Electrophysiological findings in paraneoplastic retinopathy. Graefe's Arch Clin Exp Ophthalmol 1992; 230: 324-328
38. Milam AH, Dacey DM, Dizhoor DM. Recoverin immunoreactivity in mammalian cone bipolar cells. Vis Neurosci 1992; 0: 1-2
39. Milam AH, Saari JC, Jacobson SG, Lubinski WP, Feun LG, Alexander KR. Autoantibodies against retinal bipolar cells in cutaneous melanoma-associated retinopathy. Invest Ophthalmol Vis Sci 1993; 34: 91-99
40. Mizener JB, Kimura AE, Adamus G, et al. Autoimmune retinopathy in the absence of cancer. Am J Ophthalmol 1997: 123: 607-618
41. Murphy MA, Thirkill CE, Hart WM. Paraneoplastic retinopathy: a novel auto-antibody reaction associated with small cell lung carcinoma. J Neuroophthalmol 1996; 17: 77-83
42. Oohira A, Tamaki Y, Nagahara K. A case of paraneoplastic retinopathy. Jpn J Ophthalmol 1993; 37: 28-31
43. Ohnishi Y, Ohara S, SakamotoT, et al. Cancer-associated retinopathy with retinal phlebitis. Br J Ophthalmol 1993; 77: 795-798
44. Ojeda VJ. The classification of spinal cord disorders in patients with cancer. Pathology 1983; 5: 122-124
45. Pepkowitz S, Reader A. Jacobs A, et al. Paraneoplastic retinopathy: resolution with plasmapheresis. Transfusion 1993; 33 (Suppl): S275
46. Pillay N, Gibert JJ, Ebers GC, Brown JD. Internuclear ophthalmoplegia and optic neuritis: paraneoplastic effects of bronchial carcinoma. Neurology 1984; 34: 788-791
47. van der Pol BAE, Planten JTJ. A non-metastatic remote effect of lung carcinoma. Doc Ophthalmol 1997; 67: 89-94
48. Polans AS, Burton MD, Haley TL, et al. Recoverin, but not visinin, is an autoantigen in the human retina identified with a cancer-associated retinopathy. Invest Ophthalmol Vis Sci 1993; 34: 81 -90
49. Polans AS, Buczylko J, Crabb J, Palczewski K. A photoreceptor calcium binding protein is recognized by autoantibodies obtained from patients with cancer-associated ertinopathy. J Cell Biol 1991; 112: 981-989
50. Purvin VA. Anterior ischemic optic neuropathy secondary to interferon alfa. Arch Ophthalmol 1995; 113: 1041-1044
51. Ripps H, Carr RE, Siegel IM, Greenstein VC. Functional abnormalities in vincristine-induced nicht blindness. Invest Ophthalmol Vis Sci 1984; 25: 787-794
52. Rizzo JF, Gittinger JW. Selective immunohistochemical staining in the paraneoplastic retinopathy syndrome. Ophthalmology 1992; 99: 1286-1295
53. Rizzo JF, Volpe NF. Cancer-associated retinopathy. In: Pepose JS, Holland GN, Wilhelmus KR (Hrsg.). Ocular infection and immunity. Mosby 1996; pp 585-599
54. Rowe SE, Trobe JD, Sieving PA. Idiopathic photoreceptor dysfunction causes unexplained visual acuity loss in later adulthood. Ophthalmology 1990; 97: 1632-1637
55. Rudge P. Optic neuritis as a complication of carcinoma of the breast. Proc R Soc Med 1973; 66: 1106-1107
56. Sawyer RA, Selhorst JB, Zimmerman LE, Hoyt WF. Blindness caused by photoreceptor degeneration as a remote effect of cancer. Am J Ophthalmol 1976; 81: 606-613
57. de la Sayette V, Bertran F, Honnorat J, et al. Paraneoplastic cerebellar syndrome and optic neuritis with anti-CV2 antibodies. Arch Neurol 1998; 55: 405-408
58. Spence AM, Sumi SM, Ruff R. Paraneoplastic syndromes that involve the nervous system. Curr Probl Cancer 1983; 8: 4-43
59. Steffansson K, Marton LS, Dieperink ME, et al. Circulating autonatibodies to the 200,000-dalton protein of neurofilaments in the serum of healthy individuals. Science 1985; 228: 1117-1119
60. Suzuki T, Obara Y, Sato Y, et al. Cancer-associated retinopathy with presumed vasculitis. Am J Ophthalmol 1996; 122: 125-127
61. Thirkill CE. Experimental, cancer-induced retinopathy. Ocular Imunol Inflamm 1997; 5: 55-65
62. Thirkill CE, FitzGerald P, Sergott RC, et al. Cancer associated retinopathy (CAR syndrome) with antibodies reacting with retinal, optic nerve, and cancer cells. N Engl J Med 1989; 321: 1589-1594
63. Thirkill CE, Roth AM, Keltner JL. Cancer associated retinopathy. Arch Ophthalmol 1987; 105: 372-375
64. Thirkill CE, Keltner JL, Tyler NK, Roth AM. Antibody reactions with retina and cancer-associated antigens in 10 patients with cancer-associated retinopathy. Arch Ophthalmol 1993; 111: 931-937
65. Thirkill CE, Tait RC, Tyler NK, et al. The cancer-associated retinopathy antigen is a recoverin-like protein. Invest Ophthalmol Vis Sci 1992; 33: 2768-2772
66. Thirkill CE, Tait RC, Tyler NK, et al. Intraperitoneal cultivation of small-cell carcinoma induces expression of the retinal cancer-associated retinopathy antigen. Arch Ophthalmol 1993; 111: 974-978
67. Vargas Nunez JA, Bonilla Velasco F, Casas Fernandez-Tjerina J, Vaquero Ruano M. Degeneracion retiniana paraneoplasica. Med Clin 1987; 88: 431-435
68. Whitcup SM, Vistica BP, Milam AH, et al. Recoverin-associated retinopathy: a clinically and immunologically distinctive disease. AmJ Ophthalmol 1998; 126: 230-237