The utility of an alcohol oxidase reaction test to expedite the detection of toxic alcohol exposures

Academic Emergency Medicine

Volumn 7, Issue 3, 2000, Pages 294-297

  Hack, Jason B ^a   Chiang, William K ^b   Howland, Mary Ann ^b   Patel, Harini ^c   Goldfrank, Lewis R ^b  

^a EAST CAROLINA UNIVERSITY   (United States)

^b NEW YORK UNIVERSITY   (United States)

^c BELLEVUE HOSPITAL CENTER   (United States)

Author keywords

Alcohol; Alcohol oxidase; Detection

Indexed keywords

2 PROPANOL; ALCOHOL; ETHYLENE GLYCOL; METHANOL;

ALCOHOL INTOXICATION; ANION GAP; ARTICLE; CHEMICAL REACTION; COLORIMETRY; DIAGNOSTIC PROCEDURE; ENZYME MECHANISM; METABOLIC ACIDOSIS; PRIORITY JOURNAL; SALIVA ANALYSIS;

EID: 0034088791     PISSN: 10696563     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1553-2712.2000.tb01082.x     Document Type: Article

References (25)

1. Becker C. Antidotes for methanol and ethylene glycol poisoning - a REAL challenge! J Toxicol Clin Toxicol. 1997; 35: 147-8.
2. Goldfrank LR, Flomenbaum NE, Howland M, et al. Methanol, ethylene glycol and isopropanol. In: Goldfrank LR, Flomenbaum NE, Lewin NA, et al. (eds). Goldfrank's Toxicologic Emergencies, 5th ed. East Norwalk, CT: Appleton & Lange, 1994, pp 827-38.
3. Jacobsen D, Bredesen JE, Eidei I, Østborg J. Anion and osmolal gaps in the diagnosis of methanol and ethylene glycol poisoning. Acta Med Scand. 1982; 212:17-20.
4. Goldfrank LR. A perspective on the IPCS methanol and ethylene glycol document. J Toxicol Clin Toxicol. 1997; 35: 145-6.
5. Kearney J, Rees S, Chiang WK. Availability of serum methanol and ethylene glycol levels: a national survey [abstract]. J Toxicol Clin Toxicol. 1997; 35:509.
6. Burkhart K. Methanol and ethylene glycol toxicity. J Toxicol Clin Toxicol 1997; 35:149-50.
7. Wu AH, Kelly T, McKay C, Ostheimer D, Forte E, Hill D. Definitive identification of an exceptionally high methanol concentration in an intoxication of a surviving infant: methanol metabolism by first order elimination kinetics. J Forens Sci. 1995; 40:315-20.
8. Haffner H, Wehner H, Scheytt K, Besserer K. The elimination kinetics of methanol and the influence of ethanol. Int J Legal Med. 1992; 105:111-4.
9. Walker JA, Schwartzbard A, Krauss EA, Sherman RA, Eisenger RP. The missing gap. Arch Intern Med. 1986; 146: 1843-4.
10. Steinhart B. Case report: severe ethylene glycol intoxication with normal osmolal gap - "a chilling thought." J Emerg Med. 1990; 8:583-5.
11. Schelling JR, Howard RL, Winter SD, Linas SL. Increased osmolal gap in alcoholic ketoacidosis and lactic acidosis. Ann Intern Med. 1990; 113:580-2.
12. Hoffman RS, Smilkstein MJ, Howland MA, Goldfrank LR. Osmol gaps revisited: normal values and limitations. J Toxicol Clin Toxicol. 1993; 31:81-93.
13. Jacobsen D, McMartin KE. Antidotes for methanol and ethylene glycol poisoning. J Toxicol Clin Toxicol. 1997; 35:127-43.
14. Dorwart WV, Chalmers L. Comparison of methods for calculating serum osmolality from chemical concentrations, and the prognostic value of such calculations. Clin Chem. 1975; 21:190-4.
15. Kruse JA. Methanol poisoning. Intensive Care Med. 1992; 18:391-7.
16. Stelmach MZ, O'Day J. Partly reversible visual failure with methanol toxicity. Aust N Z J Ophthalmol. 1992; 20:57-64.
17. Hantson P, Duprez T, Mahieu P. Neurotoxicity to the basal ganglia shown by magnetic resonance imaging (MRI) following poisoning by methanol and other substances. J Toxicol Clin Toxicol. 1997; 35:151-61.
18. Palatnick W, Redman LW, Sitar DS, Tenenbein M. Methanol half-life during ethanol administration: implications for management of methanol poisoning. Ann Emerg Med. 1995; 26:202-7.
19. Baud FC, Bismuth C, Gamier R, et al. 4-Methylpyrazole may be an alternative to ethanol therapy for ethylene glycol intoxication in man. J Toxicol Clin Toxicol. 1986; 87:463-83.
20. Harry P, Turcant A, Bouachour G, et al. Efficacy of 4-methylpyrazole in ethylene glycol poisoning: clinical and toxicokinetic aspects. Hum Exp Toxicol. 1994; 13:61-4.
21. Sabeel AI, Kurkus J, Lindholm T. Intensified dialysis treatment of ethylene glycol intoxication. Scand J Urol Nephrol. 1995; 29:125-9.
22. Burgess E. Prolonged hemodialysis in methanol intoxication. Pharmacotherapy. 1992; 12:238-9.
23. Bergmeyer HU, Bergmeyer J, Grabi M. Methods of Enzymatic Analysis, 3 ed. Vol II, Samples, Reagents, Assessment of Results. Weinheim: Verlag chemie, 1983, pp 143-4.
24. Jones AW. Inter- and intra-individual variation in saliva/blood alcohol ratio during ethanol metabolism in man. Clin Chem. 1979; 25:1394-8.
25. Manzo L, Locatelli C, Candura SM, Costa LG. Nutrition and alcohol neurotoxicity. Neurotoxicology 1994; 15:555-66.