First total synthesis of 11-thia steroids

Synlett

Volumn , Issue 3, 2000, Pages 418-420

  Cachoux, Frédéric ^a   Ibrahim Ouali, Malika ^a   Santelli, Maurice ^a  

^a AIX MARSEILLE UNIVERSITY   (France)

Author keywords

Intramolecular Diels Alder; Orthoquinodimethane; Sulfoxide; Thia steroid; Wacker oxidation

Indexed keywords

ALKANE DERIVATIVE; KETONE DERIVATIVE; STEROID; SULFOXIDE; VINYL DERIVATIVE;

ARTICLE; CHEMICAL REACTION; DRUG SYNTHESIS; ISOMER; MOLECULAR MODEL; OXIDATION; REACTION ANALYSIS; STEROIDOGENESIS;

EID: 0034088750     PISSN: 09365214     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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29. 4, filtered and concentrated in vacuo. The residue was purified by flash chromatography (typically eluting with petroleum ether : ethyl acetate, 9:1 to 5:5) to give 0.28 g (88%) of an inseparable 3/1 mixture of two diastereoisomers 7α and 7β.