Antibiotic levels in empyemic pleural fluid

Chest

Volumn 117, Issue 6, 2000, Pages 1734-1739

  Teixeira, Lisete R ^a   Sasse, Scott A ^b   Villarino, Maria Antonia ^a   Nguyen, Tan ^b   Mulligan, Maury E ^b   Light, Richard W ^a,c  

^a VANDERBILT UNIVERSITY   (United States)

^b VA LONG BEACH HEALTHCARE SYSTEM   (United States)

^c SAINT THOMAS HOSPITAL   (United States)

Author keywords

Antibiotics; Empyema; Pleura

Indexed keywords

ANTIBIOTIC AGENT; CEFTRIAXONE; CLINDAMYCIN; GENTAMICIN; METRONIDAZOLE; PENICILLIN DERIVATIVE; VANCOMYCIN;

ANIMAL MODEL; AREA UNDER THE CURVE; ARTICLE; DRUG BLOOD LEVEL; DRUG PENETRATION; EMPYEMA; MALE; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PLEURA FLUID; PRIORITY JOURNAL; RABBIT;

EID: 0034087865     PISSN: 00123692     EISSN: None     Source Type: Journal    
DOI: 10.1378/chest.117.6.1734     Document Type: Article

References (21)

1. 1 Taryle DA, Good JT Jr, Morgan EJ III, et al. Antibiotic concentrations in human parapneumonic effusions. J Antimicrob Chemother 1981; 7:171-177
2. 2 Hughes CE, Van Scoy RE. Antibiotic therapy of pleural empyema. Semin Respir Infect 1991; 6:94-102
3. 3 Cole DR, Pung J. Penetration of cefazolin into pleural fluid. Antimicrob Agents Chemother 1977; 11:1033-1035
4. 4 Thys JP, Serruys-Schoutens E, Rocmans P, et al. Amikacin concentrations in uninfected postthoracotomy pleural fluid and in serum after intravenous and intrapleural injection. Chest 1984; 85:502-505
5. 5 Thys JP, Vanderhoeft P, Herchuelz A, et al. Penetration of aminoglycosides in uninfected pleural exudates and in pleural empyemas. Chest 1988; 93:530-532
6. 6 Panzer JD, Brown DC, Epstein WL, et al. Clindamycin levels in various body tissues and fluids. J Clin Pharmacol 1972; 12:259-262
7. 7 Elliott AM, Berning SE, Iseman MD, et al. Failure of drug penetration and acquisition of drug resistance in chronic tuberculous empyema. Tubercle Lung Dis 1995; 76:463-467
8. 8 Miglioli PA, Bertazzoni-Minelli E, Berti T. Enhancement of antibiotic antibacterial activity by experimental pleural exudates. Drugs Exp Clin Res 1987; 13:161-166
9. 9 Miglioli PA. Gentamicin distribution in tissues and pleural exudate: a comparison between bolus vs drip-infusion, microbiological assay vs enzyme multiple immunoassay technique. J Chemother 1989; 1:248-252
10. 10 Sasse S, Causing L, Mulligan M, et al. Serial pleural fluid analysis in a new experimental model of empyema. Chest 1996; 109:1043-1048
11. 11 Sasse S, Nguyen TK, Mulligan M, et al. The effects of early chest tube placement on empyema resolution. Chest 1997; 111:1679-1683
12. 12 Chapin-Robertson K, Edberg SC. Measurement of antibiotics in human body fluids: techniques and significance. In: Lorian V. Antibiotics in laboratory medicine. 3rd ed. Baltimore, MD: Williams & Wilkins, 1991; 296-358
13. 13 Chambers HF, Neu HC. Penicillins. In: Mandell GL, Bennett JE, Dolin R, eds. Principles and practice of infectious diseases. 4th ed. New York, NY: Churchill Livingstone, 1995; 233-246
14. 14 Finegold SM, Mathisen GE. Metronidazole. In: Mandell GL, Bennett JE, Dolin R, eds. Principles and practice of infectious diseases. 4th ed. New York, NY: Churchill Livingstone, 1995; 329-333
15. 15 Karchmer AW. Cephalosporins. In: Mandell GL, Bennett JE, Dolin R, eds. Principles and practice of infectious diseases. 4th ed. New York, NY: Churchill Livingstone, 1995; 247-263
16. 16 Fekety R. Vancomycin and teicoplanin. In: Mandell GL, Bennett JE, Dolin R, eds. Principles and practice of infectious diseases. 4th ed. New York, NY: Churchill Livingstone, 1995; 346-353
17. 17 Steigbigel NH. Macrolides and clindamycin. In: Mandell GL, Bennett JE, Dolin R, eds. Principles and practice of infectious diseases. 4th ed. New York, NY: Churchill Livingstone, 1995; 334-345
18. 18 Lietman PS. Aminoglycosides and spectinomycin. In: Mandell GL, Douglas RG, Bennett JE, eds. Principles and practice of infectious diseases. 3rd ed. New York, NY: Churchill Livingstone, 1990; 269-283
19. 19 Vandeaux P, Waldvogel FA. Gentamicin inactivation in purulent exudates: the role of cell lysis. J Infect Dis 1980; 142:586-593
20. 20 Shohet I, Yellin A, Meyerovitch J, et al. Pharmacokinetics and therapeutic efficacy of gentamicin in an experimental pleural empyema rabbit model. Antimicrob Agent Chemother 1987; 31:982-985
21. 21 Light, RW. Pleural diseases. 3rd ed. Baltimore, MD: Williams & Wilkins, 1995; 1-6