Acute isoniazid neurotoxicity during preventive therapy

Critical Care Medicine

Volumn 28, Issue 2, 2000, Pages 567-568

  Martinjak Dvorsek, Irma ^a   Gorjup, Vojka ^a   Horvat, Matija ^a   Noc, Marko ^a  

^a UNIVERSITY MEDICAL CENTRE LJUBLJANA   (Slovenia)

Author keywords

Acute neurotoxicity; Coma; Metabolic acidosis; Preventive isoniazid treatment; Tonic clonic seizures

Indexed keywords

CLINDAMYCIN; DIAZEPAM; ETHAMBUTOL; ISONIAZID; MIDAZOLAM; NETILMICIN; PYRIDOXINE; TUBERCULOSTATIC AGENT;

ADOLESCENT; ANTIBIOTIC THERAPY; ARTICLE; ARTIFICIAL VENTILATION; CASE REPORT; COMA; DRUG INDUCED DISEASE; FEMALE; HUMAN; NEUROTOXICITY; PNEUMONIA; PRIORITY JOURNAL; SEDATION; TONIC CLONIC SEIZURE; TUBERCULOSIS;

EID: 0034087634     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/00003246-200002000-00047     Document Type: Article

References (5)

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2. 2. Wason S, Lacouture PG, Lovejoy FH Jr: Single high-dose pyridoxine treatment for isoniazid overdose. JAMA 1981; 246:1102-1104
3. 3. Asnis DS, Bhat JG, Melchert AF: Reversible seizures and mental status changes in a dialysis patient on isoniazid preventive therapy. Ann Pharmacother 1993; 27:444-446
4. 4. Alvarez FG, Guntupalli KK: Isoniazid overdose: four case reports and review of the literature. Intensive Care Med 1995; 21: 641-644
5. 5. Leppert D, Waespe W: Neurotoxicity of antituberculous drugs in a patient without active tuberculosis. Ital J Neurol Sci 1988; 9:31-34