Assessment of hepatitis C virus RNA and genotype from 6807 patients with chronic hepatitis C in the United States

Journal of Viral Hepatitis

Volumn 7, Issue 3, 2000, Pages 196-202

  Blatt, L M ^a   Mutchnick, M G ^b   Tong, M J ^c   Klion, F M ^d   Lebovics, E ^e   Freilich, B ^f   Bach, N ^g   Smith, C ^h   Herrera, J ⁱ   Tobias, H ^j   Conrad, A ^a   Schmid, P ^a   McHutchison, John G ^k  

^a National Genetics Institute   (United States)

^b WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c HUNTINGTON MEMORIAL HOSPITAL   (United States)

^d PRIVATE PRACTICE   (United States)

^e NEW YORK MEDICAL COLLEGE   (United States)

^f Consultants in Gastroenterology ^*  (United States)

^g MOUNT SINAI MEDICAL CENTER   (United States)

^h Minnesota Gastroenterology   (United States)

ⁱ UNIVERSITY OF SOUTH ALABAMA   (United States)

^j The Concord Medical Group   (United States)

^k SCRIPPS CLINIC   (United States)

more..

Author keywords

HCV genotype; Hepatitis C; Serum HCV RNA

Indexed keywords

VIRUS RNA;

ARTICLE; GENE FREQUENCY; GENETIC ANALYSIS; GENOTYPE; HEPATITIS C; HEPATITIS C VIRUS; HUMAN; INFECTION RISK; MAJOR CLINICAL STUDY; NONHUMAN; PRIORITY JOURNAL; RNA ANALYSIS; UNITED STATES; VIRUS LOAD;

AFRICAN CONTINENTAL ANCESTRY GROUP; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENOTYPE; HEPACIVIRUS; HEPATITIS C, CHRONIC; HUMANS; MALE; RNA, VIRAL; UNITED STATES; VIRAL LOAD;

EID: 0034087303     PISSN: 13520504     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2893.2000.00221.x     Document Type: Article

References (25)

1. 1 Fattovich G, Giustina G, Degos F et al. Morbidity and mortality in compensated cirrhosis type C: a retrospective follow-up study of 384 patients. Gastroenterology 1997; 112: 463-472.
2. 2 Tong MJ, Lee S-Y, Hwang S-J et al. Evidence for hepatitis C viral infection in patients with primary hepatocellular carcinoma. West J Med 1994; 160: 133-138.
3. 3 Hoofnagle J. Hepatitis C: the clinical spectrum of disease. Hepatol Suppl 1997; 26: 15S-20S.
4. 4 Alter MJ. Epidemiology of hepatitis C in the West. Semin Liver Dis 1995; 15: 5-14.
5. 5 Miller RH, Purcell RH. Hepatitis C virus shares amino acid sequence similarity with pestiviruses and flaviviruses as well as members of two plant virus supergroups. Proc Natl Acad Sci USA 1990; 87: 2057-2061.
6. 6 Choo Q-L, Kuo G, Weiner AJ, Overby LR, Bradley DW, Houghton M. Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome. Science 1989; 244: 359-362.
7. 7 Kato N, Hijikata M, Nakagawa M et al. Molecular structure of the Japanese hepatitis C viral genome. FEBS Lett 1991; 280: 325-328.
8. 8 Simmonds P, Smith DB, McOmish F et al. Identification of genotypes of hepatitis C virus by sequence comparisons in the core, E1 and NS-5 regions. J Gen Virol 1994; 75: 1053-1061.
9. 9 Hoofnagle JH, Di Bisceglie AM. The treatment of chronic viral hepatitis. N Engl J Med 1997; 336: 347-356.
10. 10 Zein NN, Rakela J, Krawitt EL et al. Hepatitis C virus genotypes in the United States: epidemiology, pathogenicity, and response to interferon therapy. Ann Intern Med 1996; 125: 634-639.
11. 11 McHutchison JG, Gordon SC, Schiff ER et al. Interferon alfa-2b alone or in combination with ribavirin as initial treatment for chronic hepatitis C. Hepatitis Interventional Therapy Group. N Engl J Med 1998; 339: 1485-1492.
12. 12 Mihm S, Fayyazi A, Hartmann H, Ramadori G. Analysis of histopathological manifestations of chronic hepatitis C virus infection with respect to virus genotype. Hepatology 1997; 25: 735-739.
13. 13 Zein NN, Poterucha JJ, Gross JB Jr et al. Increased risk of hepatocellular carcinoma in patients infected with hepatitis C genotype 1b. Am J Gastroenterol 1996; 91: 2560-2562.
14. 14 Hatzakis A, Katsoulidou A, Kaklamani E et al. Hepatitis C virus 1b is the dominant genotype in HCV-related carcinogenesis: a case-control study. Int J Cancer 1996; 68: 51-53.
15. 15 Sabin CA, Telfer P, Phillips AN, Bhagani S, Lee CA. The association between hepatitis C virus genotype and human immunodeficiency virus disease progression in a cohort of hemophilic men. J Infect Dis 1997; 175: 164-168.
16. 16 Lau JYN, Davis GL, Prescott LE et al. Distribution of hepatitis C virus genotypes determined by line probe assay in patients with chronic hepatitis C seen at tertiary referral centers in the United States. Ann Intern Med 1996; 124: 868-876.
17. 17 Takada N, Takase S, Takada A, Date T. Differences in the hepatitis C virus genotypes in different countries. J Hepatol 1993; 17: 277-283.
18. 18 Picciotto A, Campo N, Brizzolara R et al. HCV-RNA levels play an important role independently of genotype in predicting response to interferon therapy. Eur J Gastroenterol Hepatol 1997; 9: 67-69.
19. 19 Tong MJ, Blatt LM, McHutchison JG, Hurr Y, Co R, Conrad A. Early prediction of response to interferon alfa 2b therapy in chronic hepatitis C patients using viral and biochemical characteristics: a comparison. Hepatology 1997; 26: 1640-1645.
20. 20 Hawkins A, Davidson F, Simmonds P. Comparison of plasma virus loads among individuals infected with hepatitis C virus (HCV) genotypes 1, 2, and 3 by quantiplex HCV RNA assay versions 1 and 2, Roche Monitor assay, and an in-house limiting dilution method. J Clin Microbiol 1997; 35: 187-192.
21. 21 Blatt LM, Tong M, McHutchison J, Conrad A, Schmid P. Discordance between serum alanine aminotransferase (ALT) and virological response to interferon alfa-2b in chronic hepatitis C patients with high and low pre-treatment serum hepatitis C virus RNA titers. J Interferon Cytokine Res 1998; 18: 75-80.
22. 22 Stuyver L, Rossau R, Wyseur A et al. Typing of hepatitis C virus isolates and characterization of new subtypes using a line probe assay. J Gen Virol 1993; 74: 1093-1102.
23. 23 Simmonds P, Alberti A, Alter HJ et al. A proposed system for the nomenclature of hepatitis C viral genotypes. Hepatology 1994; 19: 1321-1324.
24. 24 Dusheiko GM, Simmonds P. Sequence variability of hepatitis C virus and its clinical relevance. J Viral Hepat 1994; 1: 3-15.
25. 25 Reddy R, Hoofnagle J, Tong M et al. Low rates of response to interferon in African Americans with chronic hepatitis C (abstr). Hepatology 1998; 28: 1339.