Upregulation of galanin binding sites and GalR1 mRNA levels in the mouse locus coeruleus following chronic morphine treatments and precipitated morphine withdrawal

Neuropsychopharmacology

Volumn 23, Issue 2, 2000, Pages 127-137

  Zachariou, Venetia ^a   Thome, Johannes ^a   Parikh, Kavita ^a   Picciotto, Marina R ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Drug dependence; Galanin receptors; Locus coeruleus, In situ hybridization; Mouse; Receptor autoradiography

Indexed keywords

CYCLIC AMP; GALANIN; GALANIN RECEPTOR; MESSENGER RNA; MORPHINE; NALTREXONE;

ANIMAL EXPERIMENT; ARTICLE; BINDING SITE; CONTROLLED STUDY; DRUG WITHDRAWAL; FEMALE; LOCUS CERULEUS; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR UPREGULATION;

ANIMALS; AUTORADIOGRAPHY; BEHAVIOR, ANIMAL; DRUG ADMINISTRATION SCHEDULE; FEMALE; GALANIN; IN SITU HYBRIDIZATION; IODINE RADIOISOTOPES; LOCUS COERULEUS; MICE; MICE, INBRED C57BL; MORPHINE; NALTREXONE; NUCLEUS ACCUMBENS; RECEPTORS, GALANIN; RECEPTORS, NEUROPEPTIDE; RNA, MESSENGER; SUBSTANCE WITHDRAWAL SYNDROME; UP-REGULATION; VENTRAL TEGMENTAL AREA;

EID: 0034086917     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0893-133X(00)00094-4     Document Type: Article

References (32)

1. Aghajanian G.K. Tolerance of locus coeruleus neurones to morphine and suppression of withdrawal response by clonidine. Nature. 276:1978;186-188.
2. Benfenati F., Cimino M., Agnati L.F., Fuxe K. Quantitative autoradiography of central neurotransmitter receptors. Methodological and statistical aspects with special reference to computer-assisted image analysis Acta Physiol Scand. 128:1986;129-146.
3. Duman R.S., Tallman J.F., Nestler E.J. Acute and chronic opiate-regulation of adenylate cyclase in brain. Specific effects in locus coeruleus J Pharmacol Exp Ther. 246:1988;1033-1039.
4. Etemadzadeh E. Cerebral dopamine and noradrenaline in mice withdrawn from repeated morphine treatment and development of tolerance to a test dose of morphine. Gen Pharmacol. 25:1994;623-629.
5. Franklin K.B.J., Paxinos G. The Mouse Brain in Stereotaxic Coordinates. 1997;Academic Press, San Diego.
6. Guitart X., Nestler E.J. Identification of morphine- and cyclic AMP-regulated phosphoproteins (MARPPs) in the locus coeruleus and other regions of rat brain. Regulation by acute and chronic morphine J Neurosci. 9:1989;4371-4387.
7. Gustafson E.L., Smith K.E., Durkin M.M., Gerald C., Branchek T.A. Distribution of a rat galanin receptor mRNA in rat brain. Neuroreport. 7:1996;953-957.
8. Habert-Ortoli E., Amiranoff B., Loquet I., Laburthe M., Mayaux J.F. Molecular cloning of a functional human galanin receptor. Proc Natl Acad Sci USA. 91:1994;9780-9783.
9. Holmes P.V., Blanchard D.C., Blanchard R.J., Brady L.S., Crawley J.N. Chronic social stress increases levels of preprogalanin mRNA in the rat locus coeruleus. Pharmacol Biochem Behav. 50:1995;655-660. a.
10. Holmes P.V., de Bartolomeis A., Koprivica V., Crawley J.N. Lack of effect of chronic morphine treatment and naloxone-precipitated withdrawal on tyrosine hydroxylase, galanin, and neuropeptide Y mRNA levels in the rat locus coeruleus. Synapse. 19:1995;197-205. b.
11. Holmes P.V., Koprivica V., Chough E., Crawley J.N. Intraventricular administration of galanin does not affect behaviors associated with locus coeruleus activation in rats. Peptides. 15:1994;1303-1308.
12. Ikeda M., Dewar D., McCulloch J. Galanin receptor binding sites in the temporal and occipital cortex are minimally affected in Alzheimer's disease. Neurosci Lett. 192:1995;37-40.
13. Kadowaki K., Emson P.C. Increase in galanin gene expression in locus coeruleus neurones of the rat following reserpine treatment. Brain Res Mol Brain Res. 15:1992;156-160.
14. Kolakowski L.F. Jr., O'Neill G.P., Howard A.D., Broussard S.R., Sullivan K.A., Feighner S.D., Sawzdargo M., Nguyen T., Kargman S., Shiao L.L., Hreniuk D.L., Tan C.P., Evans J., Abramovitz M., Chateauneuf A., Coulombe N., Ng G., Johnson M.P., Tharian A., Khoshbouei H., George S.R., Smith R.G., O'Dowd B.F. Molecular characterization and expression of cloned human galanin receptors GALR2 and GALR3. J Neurochem. 71:1998;2239-2251.
15. Loh H.H., Smith A.P. Molecular characterization of opioid receptors. Ann Rev Pharmacol Toxicol. 30:1990;123-147.
16. Maldonado R., Blendy J.A., Tzavara E., Gass P., Roques B.P., Hanoune J., Schutz G. Reduction of morphine abstinence in mice with a mutation in the gene encoding CREB. Science. 273:1996;657-659.
17. Marek P., Ben-Eliyahu S., Vaccarino A.L., Liebeskind J.C. Delayed application of MK-801 attenuates development of morphine tolerance in rats. Brain Res. 558:1991;163-165.
18. Melander T., Hokfelt T., Nilsson S., Brodin E. Visualization of galanin binding sites in the rat central nervous system. Eur J Pharmacol. 124:1986;381-382. a.
19. Melander T., Hokfelt T., Rokaeus A., Cuello A.C., Oertel W.H., Verhofstad A., Goldstein M. Coexistence of galanin-like immunoreactivity with catecholamines, 5-hydroxytryptamine, GABA, and neuropeptides in the rat CNS. J Neurosci. 6:1986;3640-3654. b.
20. Nestler E.J. Molecular mechanisms of drug addiction. J Neurosci. 12:1992;2439-2450.
21. Nestler E.J., Hope B.T., Widnell K.L. Drug addiction. A model for the molecular basis of neural plasticity Neuron. 11:1993;995-1006.
22. Nishibori M., Oishi R., Itoh Y., Saeki K. Galanin inhibits noradrenaline-induced accumulation of cyclic AMP in the rat cerebral cortex. J Neurochem. 51:1988;1953-1955.
23. Pieribone V.A., Xu Z.Q., Zhang X., Grillner S., Bartfai T., Hokfelt T. Galanin induces a hyperpolarization of norepinephrine-containing locus coeruleus neurons in the brainstem slice. Neuroscience. 64:1995;861-974.
24. Rasmussen K., Beitner-Johnson D.B., Krystal J.H., Aghajanian G.K., Nestler E.J. Opiate withdrawal and the rat locus coeruleus. Behavioral, electrophysiological, and biochemical correlates J Neurosci. 10:1990;2308-2317.
25. Seutin V., Verbanck P., Massotte L., Dresse A. Galanin decreases the activity of locus coeruleus neurons in vitro. Eur J Pharmacol. 164:1989;373-376.
26. Sevcik J., Finta E.P., Illes P. Galanin receptors inhibit the spontaneous firing of locus coeruleus neurones and interact with mu-opioid receptors. Eur J Pharmacol. 230:1993;223-230.
27. Skofitsch G., Sills M.A., Jacobowitz D.M. Autoradiographic distribution of 125I-galanin binding sites in the rat central nervous system. Peptides. 7:1986;1029-1042.
28. Wang S., Hashemi T., He C., Strader C., Bayne M. Molecular cloning and pharmacological characterization of a new galanin receptor subtype. Mol Pharmacol. 52:1997;337-343. a.
29. Wang S., He C., Hashemi T., Bayne M. Cloning and expression characterization of a novel galanin receptor. J Biol Chem. 272:1997;31949-31952. b.
30. Xu Z.Q., Shi T.J., Hokfelt T. Galanin/GMAP- and NPY-like immunoreactivities in locus coeruleus and noradrenergic nerve terminals in the hippocampal formation and cortex with notes on the galanin-R1 and -R2 receptors. J Comp Neurol. 392:1998;227-251.
31. Zachariou V., Parikh K., Picciotto M.R. Centrally administered galanin blocks morphine place preference in the mouse. Brain Res. 831:1999;33-42.
32. Zachariou V., Picciotto M.R. Cloning and characaterization of the GalR1 promoter region. Soc Neurosci Abstr. 25:1999;422.