Epitope mapping of monoclonal antibodies specific for a macrophage lectin: A calcium-dependent epitope is in the carbohydrate recognition domain

Molecular Immunology

Volumn 37, Issue 3-4, 2000, Pages 151-160

  Kimura, Toshifumi ^a,b   Hosoi, Takeshi ^a,c   Yamamoto, Kazuo ^a   Suzuki, Noriko ^a,d   Imai, Yasuyuki ^a,e   Irimura, Tatsuro ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b BANYU PHARMACEUTICAL CO LTD   (Japan)

^c MITSUBISHI TANABE PHARMA CORPORATION   (Japan)

^d JOHNS HOPKINS UNIVERSITY   (United States)

^e UNIVERSITY OF SHIZUOKA   (Japan)

Author keywords

Chimeric protein; Ligand induced binding sites; MMGL

Indexed keywords

CALCIUM; CARBOHYDRATE; EPITOPE; GALACTOSE; LECTIN; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY LOM 11; N ACETYLGALACTOSAMINE; TRYPSIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CONFORMATION; CONTROLLED STUDY; EPITOPE MAPPING; LIGAND BINDING; MACROPHAGE; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; RAT;

ANIMALIA;

EID: 0034086601     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0161-5890(00)00027-4     Document Type: Article

References (30)

1. Chiacchia, K.B., Drickamer, K., 1984. Direct evidence for the transmembrane orientation of the hepatic glycoprotein receptors. J. Biol. Chem. 259, 15440-15446.
2. d, has a functional carbohydrate recognition domain. Immunity 1, 785-792.
3. Drickamer, K., 1988. Two distinct classes of carbohydrate recognition domains in animal lectins. J. Biol. Chem. 263, 9557-9560.
4. Drickamer, K., 1992. Engineering galactose-binding activity into a C-type mannose-binding protein. Nature 360, 183-186.
5. Hemmerich, S., Leffler, H., Rosen, S.D., 1995. Structure of the Oglycans in GlyCAM-1, an endothelial-derived ligand for L-selectin. J. Biol. Chem. 270, 12035-12047.
6. Hosoi, T., Imai, Y., Irimura, T., 1998. Coordinated binding of sugar, calcium, and antibody to macrophage C-type lectin. Glycobiology 8, 791-798.
7. Ii, M., Kurata, H., Itoh, N., Yamashina, I., Kawasaki, T., 1990. Molecular cloning and sequence analysis of cDNA encoding the macrophage lectin specific for galactose and N-acetylgalactosamine. J. Biol. Chem. 265, 11295-11298.
8. Imai, Y., Irimura, T., 1994. Quantitative measurement of carbohydrate binding activity of mouse macrophage lectin. J. Immunol. Methods 171, 23-31.
9. Imai, Y., Singer, M.S., Fennie, C., Lasky, L.A., Rosen, S.D., 1991. Identification of a carbohydrate-based endothelial ligand for a lymphocyte homing receptor. J. Cell. Biol. 113, 1213-1221.
10. Imai, Y., Lasky, L.A., Rosen, S.D., 1993. Sulphation requirement for GlyCAM, an endothelial ligand for L-selectin. Nature 361, 555-557.
11. Imai, Y., Akimoto, Y., Mizuochi, S., Kimura, T., Hirano, H., Irimura, T., 1995. Restricted expression of galactose/N-acetylgalactosamine-specific macrophage C-type lectin to connective tissue and to metastatic lesions in mouse lung. Immunology 86, 591-598.
12. Karlhofer, F., Ribaudo, R.K., Yokoyama, W.E., 1992. MHC class I alloantigen specificity of Ly-49(+) IL-2-activated natural killer cells. Nature 358, 66-70.
13. Kawakami, K., Yamamoto, K., Toyoshima, S., Osawa, T., Irimura, T., 1994. Dual function of macrophage galactose/N-acetylgalactosamine-specific lectins: glycoprotein uptake and tumoricidal cellular recognition. Jpn. J. Cancer Res. 85, 744-749.
14. Kimura, T., Imai, Y., Irimura, T., 1995. Calcium-dependent conformation of a mouse macrophage calcium-type lectin. Carbohydrate binding activity is stabilized by an antibody specific for a calcium-dependent epitope. J. Biol. Chem. 270, 16056-16062.
15. Konami, Y., Yamamoto, K., Osawa, T., 1991a. The primary structures of two types of the Ulex europeus seed lectin. J. Biochem. (Tokyo) 109, 650-658.
16. Konami, Y., Yamamoto, K., Toyoshima, S., Osawa, T., 1991b. The primary structure of the Laburunum alpinum seed lectin. FEBS Letters 286, 33-38.
17. Mizuochi, S., Akimoto, Y., Imai, Y., Hirano, H., Irimura, T., 1997. Unique tissue distribution of a mouse macrophage C-type lectin. Glycobiology 7, 137-146.
18. Oda, S., Sato, M., Toyoshima, S., Osawa, T., 1988. Purification and characterization of a lectin-like molecule specific for galactose/N-acetyl-galactosamine from tumoricidal macrophages. J. Biochem. (Tokyo) 104, 600-605.
19. Oda, S., Sato, M., Toyoshima, S., Osawa, T., 1989. Binding of activated macrophages to tumor cells through a macrophage lectin and its role in macrophage tumoricidal activity. J. Biochem. (Tokyo) 105, 1040-1043.
20. Ozaki, K., Ii, M., Itoh, N., Kawasaki, T., 1992. Expression of a functional asialogycoprotein receptor through transfection of a cloned cDNA that encodes a macrophage lectin. J. Biol. Chem. 267, 9229-9235.
21. Pouyani, T., Seed, B., 1995. PSGL-1 recognition of P-selectin is controlled by a tyrosine sulfation consensus at the PSGL-1 amino terminus. Cell. 83, 333-343.
22. Russell, M.E., Utans, U., Wallace, A.F., Liang, P., Arceci, R.J., Karnovsky, M.J., Wyner, L.R., Yamashita, Y., Tarn, C., 1994. Identification and upregulation of galactose/N-acetylgalactosamine macrophage lectin in rat cardiac allografts with arteriosclerosis. J. Clin. Invest. 94, 722-730.
23. Sakamaki, T., Imai, Y., Irimura, T., 1995. Enhancement in accessibility to macrophages by modification of mucin-type carbohydrate chains on a tumor cell line: role of a C-type lectin of macrophages. J. Leukoc. Biol. 57, 407-414.
24. Sako, D., Comess, K.M., Barone, K.M., Camphausen, R.T., Cumming, D.A., Shaw, G.D., 1995. A sulfated peptide segment at the amino terminus of PSGL-1 is critical for P-selectin binding. Cell. 83, 323-331.
25. Sato, M., Kawakami, K., Osawa, T., Toyoshima, S., 1992. Molecular cloning and expression of cDNA encoding a galactose/N-acetyl-galactosamine specific lectin on mouse tumoricidal macrophages. J. Biochem. (Tokyo) 111, 331-336.
26. Suzuki, N., Yamamoto, K., Toyoshima, S., Osawa, T., Irimura, T., 1996. Molecular cloning and expression of cDNA encoding human macrophage C-type lectin. Its unique carbohydrate binding specificity for Tn antigen. J. Immunol. 156, 128-135.
27. Tsuiji, M., Fujimori, M., Seldin, M.F., Taketo, M.M., Irimura, T., 1999. Genomic structure and chromosomal location of the mouse macrophage C-type lectin gene. Immunogenetics 50, 67-70.
28. Weis, W.I., Kahn, R., Fourme, R., Drickamer, K., Hendrickson, W.A., 1991. Structure of the calcium-dependent lectin domain from a rat mannose-binding protein determined by MAD phasing. Science 254, 1608-1615.
29. Weis, W.I., Drickamer, K., Hendrickson, W.A., 1992. Structure of a C-type mannose-binding protein complexed with an oligosaccharide. Nature 360, 127-134.
30. Yamamoto, K., Konami, Y., Osawa, T., Irimura, T., 1992. Alteration of the carbohydrate-binding specificity of the Bauhinia purpurea lectin through the preparation of a chimeric lectin. J. Biochem. (Tokyo) 111, 87-90.