메뉴 건너뛰기




Volumn 27, Issue 7, 2000, Pages 488-493

Cardiovascular effects of chronic nitric oxide synthase inhibition in genetically hypertensive rats

Author keywords

Blood pressure; Genetically hypertensive rat; N( ) nitro L arginine methyl ester; Nitric oxide; Nitric oxide synthase inhibition; Rat hindquarter

Indexed keywords

ACETYLCHOLINE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITROPRUSSIDE SODIUM; NORADRENALIN;

EID: 0034086501     PISSN: 03051870     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1440-1681.2000.03279.x     Document Type: Article
Times cited : (10)

References (36)
  • 1
    • 0028969847 scopus 로고
    • Nitric oxide activity in the human coronary circulation. Impact of risk factors for coronary atherosclerosis
    • 1. Quyyumi AA, Dakak N, Andrews NP et al. Nitric oxide activity in the human coronary circulation. Impact of risk factors for coronary atherosclerosis. J. Clin. Invest. 1995; 95: 1747-55.
    • (1995) J. Clin. Invest. , vol.95 , pp. 1747-1755
    • Quyyumi, A.A.1    Dakak, N.2    Andrews, N.P.3
  • 2
    • 0028314525 scopus 로고
    • Nitric oxide regulates basal systemic and pulmonary vascular resistance in healthy humans
    • 2. Stamler JS, Loh E, Roddy MA, Currie KE, Creager MA. Nitric oxide regulates basal systemic and pulmonary vascular resistance in healthy humans. Circulation 1994; 89: 2035-44.
    • (1994) Circulation , vol.89 , pp. 2035-2044
    • Stamler, J.S.1    Loh, E.2    Roddy, M.A.3    Currie, K.E.4    Creager, M.A.5
  • 4
    • 0025883342 scopus 로고
    • Nitric oxide: Physiology, pathophysiology and pharmacology
    • 4. Moncada S, Palmer RM, Higgs EA. Nitric oxide: Physiology, pathophysiology and pharmacology. Pharmacol. Rev. 1991; 43: 109-42.
    • (1991) Pharmacol. Rev. , vol.43 , pp. 109-142
    • Moncada, S.1    Palmer, R.M.2    Higgs, E.A.3
  • 6
    • 0030892215 scopus 로고    scopus 로고
    • Endothelial dysfunction: Clinical implications
    • 6. Drexler H. Endothelial dysfunction: Clinical implications. Prog. Cardiovasc. Dis. 1997; 39: 287-324.
    • (1997) Prog. Cardiovasc. Dis. , vol.39 , pp. 287-324
    • Drexler, H.1
  • 7
    • 0019195506 scopus 로고
    • The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine
    • 7. Furchgott RF, Zawadzki JV. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature 1980; 288: 373-6.
    • (1980) Nature , vol.288 , pp. 373-376
    • Furchgott, R.F.1    Zawadzki, J.V.2
  • 8
    • 0030795934 scopus 로고    scopus 로고
    • Selective inhibitors of neuronal nitric oxide synthase: Is no NOS really good NOS for the nervous system?
    • 8. Moore PK, Handy RL. Selective inhibitors of neuronal nitric oxide synthase: Is no NOS really good NOS for the nervous system? Trends Pharmacol. Sci. 1997; 18: 204-11.
    • (1997) Trends Pharmacol. Sci. , vol.18 , pp. 204-211
    • Moore, P.K.1    Handy, R.L.2
  • 9
    • 0025011716 scopus 로고
    • Characterization of three inhibitors of endothelial nitric oxide synthase in vitro and in vivo
    • 9. Rees DD, Palmer RM, Schulz R, Hodson HF, Moncada S. Characterization of three inhibitors of endothelial nitric oxide synthase in vitro and in vivo. Br. J. Pharmacol. 1990; 101: 746-52.
    • (1990) Br. J. Pharmacol. , vol.101 , pp. 746-752
    • Rees, D.D.1    Palmer, R.M.2    Schulz, R.3    Hodson, H.F.4    Moncada, S.5
  • 10
    • 0028176918 scopus 로고
    • ω-nitro-L-arginine methyl ester on vasodilator responses to acetylcholine, bradykinin, and substance P
    • ω-nitro-L-arginine methyl ester on vasodilator responses to acetylcholine, bradykinin, and substance P. Eur. J. Pharmacol. 1994; 254: 207-12.
    • (1994) Eur. J. Pharmacol. , vol.254 , pp. 207-212
    • Santiago, J.A.1    Garrison, E.A.2    Kadowitz, P.J.3
  • 11
    • 0032916427 scopus 로고    scopus 로고
    • A large blood pressure-raising effect of nitric oxide synthase inhibition in humans
    • 11. Sander M, Chavoshan B, Victor RG. A large blood pressure-raising effect of nitric oxide synthase inhibition in humans. Hypertension 1999; 33: 937-42.
    • (1999) Hypertension , vol.33 , pp. 937-942
    • Sander, M.1    Chavoshan, B.2    Victor, R.G.3
  • 12
    • 0029054512 scopus 로고
    • Nitric oxide and its putative role in hypertension
    • 12. Dominiczak AF, Bohr DF. Nitric oxide and its putative role in hypertension. Hypertension 1995; 25: 1202-11.
    • (1995) Hypertension , vol.25 , pp. 1202-1211
    • Dominiczak, A.F.1    Bohr, D.F.2
  • 13
    • 0021705651 scopus 로고
    • Decreased endothelium-dependent relaxation in New Zealand genetic hypertension rats
    • 13. Winquist RJ, Bunting PB, Baskin EP, Wallace AA. Decreased endothelium-dependent relaxation in New Zealand genetic hypertension rats. J. Hypertens. 1984; 2: 541-5.
    • (1984) J. Hypertens. , vol.2 , pp. 541-545
    • Winquist, R.J.1    Bunting, P.B.2    Baskin, E.P.3    Wallace, A.A.4
  • 14
    • 0030957911 scopus 로고    scopus 로고
    • ω-nitro-L-arginine methyl ester affects blood pressure and cardiovascular structure in the genetically hypertensive rat strain
    • ω-nitro-L-arginine methyl ester affects blood pressure and cardiovascular structure in the genetically hypertensive rat strain. Clin. Exp. Pharmacol. Physiol. 1997; 24: 433-5.
    • (1997) Clin. Exp. Pharmacol. Physiol. , vol.24 , pp. 433-435
    • Ledingham, J.M.1    Laverty, R.2
  • 15
    • 0014267242 scopus 로고
    • The New Zealand strain of rats with genetic hypertension
    • 15. Phelan EL. The New Zealand strain of rats with genetic hypertension. N.Z. Med. J. 1968; 67: 334-44.
    • (1968) N.z. Med. J. , vol.67 , pp. 334-344
    • Phelan, E.L.1
  • 17
    • 0013656102 scopus 로고
    • Circulatory properties of iso-thioureas, guanidines, iso-ureas and amidines
    • 17. Smirk FH, Fastier FN. Circulatory properties of iso-thioureas, guanidines, iso-ureas and amidines. J. Pharmacol. Exp. Ther. 1947; 89: 256-70.
    • (1947) J. Pharmacol. Exp. Ther. , vol.89 , pp. 256-270
    • Smirk, F.H.1    Fastier, F.N.2
  • 18
    • 0018065039 scopus 로고
    • Direct evidence that the greater contractility of resistance vessels in spontaneously hypertensive rats is associated with a narrowed lumen, a thickened media, and an increased number of smooth muscle cell layers
    • 18. Mulvany MJ, Hansen OK, Aalkjaer C. Direct evidence that the greater contractility of resistance vessels in spontaneously hypertensive rats is associated with a narrowed lumen, a thickened media, and an increased number of smooth muscle cell layers. Circ. Res. 1978; 43: 854-64.
    • (1978) Circ. Res. , vol.43 , pp. 854-864
    • Mulvany, M.J.1    Hansen, O.K.2    Aalkjaer, C.3
  • 19
    • 0029142699 scopus 로고
    • Contribution of vascular nitric oxide to basal blood pressure in conscious spontaneously hypertensive rats and normotensive Wistar Kyoto rats
    • 19. Minami N, Imai Y, Hashimoto J, Abe K. Contribution of vascular nitric oxide to basal blood pressure in conscious spontaneously hypertensive rats and normotensive Wistar Kyoto rats. Clin. Sci. 1995; 89: 177-82.
    • (1995) Clin. Sci. , vol.89 , pp. 177-182
    • Minami, N.1    Imai, Y.2    Hashimoto, J.3    Abe, K.4
  • 20
    • 0029556917 scopus 로고
    • Role of nitric oxide in the control of blood pressure in young and adult spontaneously hypertensive rats
    • 20. Akiba Y, Yamaguchi N, Amano H et al. Role of nitric oxide in the control of blood pressure in young and adult spontaneously hypertensive rats. Clin. Exp. Pharmacol. Physiol. 1995; 22 (Suppl. 1): S142-3.
    • (1995) Clin. Exp. Pharmacol. Physiol. , vol.22 , Issue.SUPPL. 1
    • Akiba, Y.1    Yamaguchi, N.2    Amano, H.3
  • 21
    • 0030605983 scopus 로고    scopus 로고
    • Study of in vivo and in vitro resting vasodilator nitric oxide tone in normotensive and genetically hypertensive rats
    • 21. Gil-Longo J, Fernandez-Grandal D, Alvarez M, Sieira M, Orallo F. Study of in vivo and in vitro resting vasodilator nitric oxide tone in normotensive and genetically hypertensive rats. Eur. J. Pharmacol. 1996; 310: 175-83.
    • (1996) Eur. J. Pharmacol. , vol.310 , pp. 175-183
    • Gil-Longo, J.1    Fernandez-Grandal, D.2    Alvarez, M.3    Sieira, M.4    Orallo, F.5
  • 22
    • 0029815114 scopus 로고    scopus 로고
    • Nitric oxide and the regulation of blood pressure in the hypertension-prone and hypertensive-resistant Sabra rat
    • 22. Rees D, Ben-Ishay D, Moncada S. Nitric oxide and the regulation of blood pressure in the hypertension-prone and hypertensive-resistant Sabra rat. Hypertension 1996; 28: 367-71.
    • (1996) Hypertension , vol.28 , pp. 367-371
    • Rees, D.1    Ben-Ishay, D.2    Moncada, S.3
  • 23
    • 0031750260 scopus 로고    scopus 로고
    • Is the nitric oxide system involved in genetic hypertension in Dahl rats?
    • 23. Deng AY. Is the nitric oxide system involved in genetic hypertension in Dahl rats? Kidney Int. 1998; 53: 1501-11.
    • (1998) Kidney Int. , vol.53 , pp. 1501-1511
    • Deng, A.Y.1
  • 25
    • 0029862767 scopus 로고    scopus 로고
    • ω-nitro-L-arginine methyl ester on cardiovascular structure in deoxycorticosterone acetate-salt hypertensive rats
    • ω-nitro-L-arginine methyl ester on cardiovascular structure in deoxycorticosterone acetate-salt hypertensive rats. J. Hypertens. 1996; 14: 1331-9.
    • (1996) J. Hypertens. , vol.14 , pp. 1331-1339
    • Li, J.S.1    Sventek, P.2    Schiffrin, E.L.3
  • 26
    • 0002581919 scopus 로고
    • Release of endothelium-derived relaxing factor from resistance arteries in hypertension
    • 26. Angus JA, Dyke AC, Jennings GL et al. Release of endothelium-derived relaxing factor from resistance arteries in hypertension. Kidney Int. 1992; 41 (Suppl. 37): S73-8.
    • (1992) Kidney Int. , vol.41 , Issue.SUPPL. 37
    • Angus, J.A.1    Dyke, A.C.2    Jennings, G.L.3
  • 27
    • 0030040491 scopus 로고    scopus 로고
    • Vascular reactivity in mesenteric resistance arteries following chronic nitric oxide synthase inhibition in Wistar rats
    • 27. Dowell FJ, Henrion D, Duriez M, Michel JB. Vascular reactivity in mesenteric resistance arteries following chronic nitric oxide synthase inhibition in Wistar rats. Br. J. Pharmacol. 1996; 117: 341-6.
    • (1996) Br. J. Pharmacol. , vol.117 , pp. 341-346
    • Dowell, F.J.1    Henrion, D.2    Duriez, M.3    Michel, J.B.4
  • 30
    • 0030594573 scopus 로고    scopus 로고
    • Effect of nitric oxide synthase inhibition on the acetylcholine response in the perfused hind limb of rats
    • 30. Brouwers-Ceiler DL, Nelissen-Vrancken HJ, Smits JF. Effect of nitric oxide synthase inhibition on the acetylcholine response in the perfused hind limb of rats. Eur. J. Pharmacol. 1996; 307: 65-8.
    • (1996) Eur. J. Pharmacol. , vol.307 , pp. 65-68
    • Brouwers-Ceiler, D.L.1    Nelissen-Vrancken, H.J.2    Smits, J.F.3
  • 31
    • 0029793832 scopus 로고    scopus 로고
    • Use-dependent loss of acetylcholine-and bradykinin-mediated vasodilation after nitric oxide synthase inhibition. Evidence for preformed stores of nitric oxide-containing factors in vascular endothelial cells
    • 31. Davisson RL, Bates JN, Johnson AK, Lewis SJ. Use-dependent loss of acetylcholine-and bradykinin-mediated vasodilation after nitric oxide synthase inhibition. Evidence for preformed stores of nitric oxide-containing factors in vascular endothelial cells. Hypertension 1996; 28: 354-60.
    • (1996) Hypertension , vol.28 , pp. 354-360
    • Davisson, R.L.1    Bates, J.N.2    Johnson, A.K.3    Lewis, S.J.4
  • 32
    • 0026068870 scopus 로고
    • Development and mechanism of a specific supersensitivity to nitrovasodilators after inhibition of vascular nitric oxide synthesis in vivo
    • 32. Moncada S, Rees DD, Schulz R, Palmer RM. Development and mechanism of a specific supersensitivity to nitrovasodilators after inhibition of vascular nitric oxide synthesis in vivo. Proc. Natl Acad. Sci. USA 1991; 88: 2166-70.
    • (1991) Proc. Natl Acad. Sci. USA , vol.88 , pp. 2166-2170
    • Moncada, S.1    Rees, D.D.2    Schulz, R.3    Palmer, R.M.4
  • 33
    • 0013679738 scopus 로고
    • Observation of the responses of rats with spontaneous hypertension and control rats to pressor drugs and to hexamethonium
    • 33. Phelan EL, Eryetishir I, Smirk FH. Observation of the responses of rats with spontaneous hypertension and control rats to pressor drugs and to hexamethonium. Circ. Res. 1962; 10: 817-24.
    • (1962) Circ. Res. , vol.10 , pp. 817-824
    • Phelan, E.L.1    Eryetishir, I.2    Smirk, F.H.3
  • 34
    • 0013870495 scopus 로고
    • Cardiovascular reactivity in rats with spontaneous inherited hypertension and constricted renal artery hypertension
    • 34. Phelan EL. Cardiovascular reactivity in rats with spontaneous inherited hypertension and constricted renal artery hypertension. Am. Heart J. 1966; 71: 50-7.
    • (1966) Am. Heart J. , vol.71 , pp. 50-57
    • Phelan, E.L.1
  • 35
    • 0013693635 scopus 로고
    • Increased vascular reactivity in rats with genetic hypertension
    • 35. Laverty R. Increased vascular reactivity in rats with genetic hypertension. Proc. Univ. Otago Med. School 1961; 19: 23-4.
    • (1961) Proc. Univ. Otago Med. School , vol.19 , pp. 23-24
    • Laverty, R.1
  • 36
    • 0022965118 scopus 로고
    • Vascular reactivity in genetically hypertensive and spontaneously hypertensive rats
    • 36. Phelan EL, Simpson FO. Vascular reactivity in genetically hypertensive and spontaneously hypertensive rats. J. Hypertens. 1986; 4 (Suppl. 3): S57-9.
    • (1986) J. Hypertens. , vol.4 , Issue.SUPPL. 3
    • Phelan, E.L.1    Simpson, F.O.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.