Nitric oxide inhibits the basic fibroblast growth factor-stimulated migration of bovine vascular smooth muscle cells in vitro

Vasa - Journal of Vascular Diseases

Volumn 29, Issue 2, 2000, Pages 99-102

  Alfke, Heiko ^a   Kleb, B ^b   Klose, K J ^b  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

^b NONE

Author keywords

bFGF; Migration; Nitric oxide; Vascular smooth muscle cells

Indexed keywords

8 BROMO CYCLIC GMP; BASIC FIBROBLAST GROWTH FACTOR; NITRIC OXIDE; NITROPRUSSIDE SODIUM; SUPEROXIDE DISMUTASE;

ANIMAL CELL; ARTICLE; CELL MIGRATION; CELL STIMULATION; CONTROLLED STUDY; DOSE RESPONSE; MICROSCOPY; NONHUMAN; SECOND MESSENGER; VASCULAR SMOOTH MUSCLE;

EID: 0034084057     PISSN: 03011526     EISSN: None     Source Type: Journal    
DOI: 10.1024/0301-1526.29.2.99     Document Type: Article

References (11)

1. Abedi H, Zachary I. Signalling mechanisms in the regulation of vascular cell migration. Cardiovasc Research 1995; 30: 544-556.
2. Bilato C, Pauly RR, Melillo G, Monticone R, Gorelick Feldman D, Gluzband YA, et al. Intracellular signaling pathways required for rat vascular smooth muscle cell migration. Interactions between basic fibroblast growth factor and platelet-derived growth factor. J Clin Invest 1995; 96: 1905-1915.
3. Bornfeldt KE, Raines EW, Nakano T, Graves LM, Krebs EG, Ross R. Insulin-like growth factor-I and platelet-derived growth factor-BB induce directed migration of human arterial smooth muscle cells via signalling pathways that are distinct from those of proliferation. J Clin Invest 1994; 93: 1266-1274.
4. Crowley ST, Ray CJ, Nawaz D, Majack RA, Horwitz LD. Multiple growth factors are released from mechanically injured vascular smooth muscle cells. Am J Physiol; 269: H1641-1647.
5. Fingerle J, Johnson R, Clowes AW, Majewsky MW, Reidy MA. Role of platelets in smooth muscle cell proliferation and migration after vascular injury in rat carotid artery. Proc Natel Acad Sci USA 1989; 86: 8412-8416.
6. Garg UC, Hassid A. Nitric oxide-generating vasodilators and 8-bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells. J Clin Invest 1989; 83: 1774-1777.
7. Jackson CL, Reidy MA. Basic fibroblast growth factor: Its role in the control of smooth muscle cell migration. Am J Pathol 1993; 143: 1024-1031.
8. Lincoln J, Hoyle CHV, Burnstock G: Pharmacology. In: Lincoln J, Hoyle CHV, Burnstock G (eds) Nitric oxide in Health and Disease. Cambridge : Cambridge University Press 1997: 159-173.
9. Loscalzo J, Welch G. Nitric oxide and its role in the cardiovascular system. Prog Cardiovasc Dis 1995; 38: 87-104.
10. Pauly RR, Passaniti A, Bilato C, Monticone R, Cheng L, Papadopoulos N, Gluzband YA, Smith L, Weinstein C, Lakatta EG, et al. Migration of cultured vascular smooth muscle cells through a basement membrane barrier requires type IV collagenase activity and is inhibited by cellular differentiation. Circ Res 1994; 75: 41-54.
11. Sato Y, Hamanaka R, Ono J, Kuwano M, Rifkin DB, Takaki R. The stimulatory effect of PDGF on vascular smooth muscle cell migration is mediated by the induction of endogenous basic FGF. Biochem Biophys Res Commun 1991; 174: 1260-1266.