Improved Cs2CO3 promoted O-alkylation of acids

Synthetic Communications

Volumn 30, Issue 15, 2000, Pages 2687-2700

  Parrish, Jay P ^a   Dueno, Eric E ^a   Kim, Seok In ^a   Jung, Kyung Woon ^a  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBONIC ACID; CARBOXYLIC ACID; CESIUM;

ALKYLATION; ARTICLE; ESTERIFICATION; PROTON NUCLEAR MAGNETIC RESONANCE; REACTION ANALYSIS; STEREOCHEMISTRY; TEMPERATURE; THIN LAYER CHROMATOGRAPHY;

EID: 0034083499     PISSN: 00397911     EISSN: None     Source Type: Journal    
DOI: 10.1080/00397910008086893     Document Type: Article

References (20)

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16. Neither elimination nor trans-esterification was observed from the product mixtures. The only side product that was isolated was the diester (8%), derived from the double esterification of 1,2-dibromoethane (cf. entry 6, Scheme II).
17. Optical rotations of the produced products were compared with the reported values: (a) Bonner, W.A. J. Am. Chem. Soc. 1951, 73, 3126.
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20. No side products such as the epimer at C(3) and elimination products were observed within our detection limits.