Negative inotropic effects of isoprenaline on isolated left atrial assays from aged transgenic mice with cardiac over-expression of human β2-adrenoceptors

British Journal of Pharmacology

Volumn 129, Issue 7, 2000, Pages 1285-1288

  Prendergast, C E ^a   Shankley, N P ^a   Black, J W ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

CGP20712A; ICI 118,551; Inotropy; Isoprenaline; Transgenic mice

Indexed keywords

3 ISOPROPYLAMINO 1 (7 METHYL 4 INDANYLOXY) 2 BUTANOL; 5 [2 [[2 HYDROXY 3 [4 (1 METHYL 4 TRIFLUOROMETHYL 2 IMIDAZOLYL)PHENOXY]PROPYL]AMINO]ETHOXY]SALICYLAMIDE; BETA 1 ADRENERGIC RECEPTOR; BETA 1 ADRENERGIC RECEPTOR BLOCKING AGENT; BETA 2 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR BLOCKING AGENT; ISOPRENALINE;

AGE; ANIMAL TISSUE; ARTICLE; ASSAY; CONCENTRATION RESPONSE; HEART LEFT ATRIUM; INOTROPISM; MOUSE; NONHUMAN; PRIORITY JOURNAL; TRANSGENIC MOUSE;

ADRENERGIC BETA-ANTAGONISTS; AGING; ANIMALS; ATRIAL FUNCTION; CARDIOTONIC AGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION; HEART ATRIA; HUMANS; IMIDAZOLES; ISOPROTERENOL; MICE; MICE, TRANSGENIC; MYOCARDIAL CONTRACTION; PROPANOLAMINES; RECEPTORS, ADRENERGIC, BETA-1; RECEPTORS, ADRENERGIC, BETA-2;

EID: 0034080737     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0703238     Document Type: Article

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