Haemodilution improves organ function during normothermic cardiopulmonary bypass: Investigations in isolated perfused pig kidneys

Perfusion

Volumn 15, Issue 3, 2000, Pages 225-229

  Dittrich, S ^a   Schuth, A ^a   Aurich, H ^a   vonLoeper, J ^a   Grosse Siestrup, C ^b   Lange, P E ^a  

^a DEUTSCHES HERZZENTRUM BERLIN   (Germany)

^b HUMBOLDT UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD FLOW; BLOOD VISCOSITY; CARDIOPULMONARY BYPASS; CONTROLLED STUDY; FLOW KINETICS; GLOMERULUS; HEMATOCRIT; HEMODILUTION; HEMODYNAMICS; KIDNEY FUNCTION; KIDNEY VASCULAR RESISTANCE; NONHUMAN; PRIORITY JOURNAL; SWINE;

ANIMALS; BLOOD GAS ANALYSIS; BLOOD VISCOSITY; CARDIOPULMONARY BYPASS; CREATINE; HEMATOCRIT; HEMODILUTION; HEMODYNAMIC PROCESSES; KIDNEY; KIDNEY FUNCTION TESTS; SODIUM; SWINE; VASCULAR RESISTANCE;

EID: 0034079546     PISSN: 02676591     EISSN: None     Source Type: Journal    
DOI: 10.1177/026765910001500307     Document Type: Article

References (19)

1. Shin'oka T, Shum-Tim D, Jonas RA et al. Higher hematocrit improves cerebral outcome after deep hypothermic circulatory arrest. J Thorac Cardiovasc Surg 1996; 112: 1610-20.
2. Cook DJ, Orszulak TA, Daly RC. Minimum hematocrit at differing cardiopulmonary bypass temperatures in dogs. Circulation 1998; 98(suppl 19): II170-74.
3. Dittrich S, Dähnert I, Vogel M et al. Peritoneal dialysis after infant open heart surgery: observations in 27 patients. Ann Thorac Surg 1999; 68: 160-63.
4. Ranucci M, Pavesi M, Mazza E et al. Risk factors for renal dysfunction after coronary surgery: the role of cardiopulmonary bypass technique. Perfusion 1994; 9: 319-26.
5. Pathi VL, Morrison J, MacPhaden A, Martin W, McQuiston AM, Wheatley DJ. Alterations in renal microcirculation during cardiopulmonary bypass. Ann Thorac Surg 1998; 65: 993-98.
6. Heyman SN, Rosen S, Brezis M. The renal medulla: life at the edge of anoxia. Blood Purif 1997; 15: 232-42.
7. McDonald KM. Influence of blood rheology on intrarenal blood flow distribution. Am J Physiol 1976; 230: 1448-54.
8. Dittrich S, Schuth A, von Baeyer H, Grosse-Siestrup C, Lange PE, Kaczmarczyk G. Effect of blood viscosity on the function of isolated perfused porcine kidney after cold preservation. Zentralbl Chir 1998;123: 809-13.
9. Rand P, Lacombe E, Hunt H, Austin W. Viscosity of normal human blood under normothermic and hyperthermic conditions. J Appl Physiol 1964; 19: 117-22.
10. Sumpio BE, Upchurch GR, Johnson G, Jr. The influence of perfusate viscosity, RBC deformability and drag on the function of an isolated perfused rat kidney. J Surg Res 1989; 46: 4-8.
11. Wells RE, Merrill EW. Influence of flow properties of blood upon viscosity-hematocrit relationships. J Clin Invest 1962; 41: 1591-98.
12. Halmagyi D, Goodman AH. Vascular resistance and oxygen transport as functions of hematocrit. Resuscitation 1974; 3: 165-70.
13. Roos A. Poiseuille's law and its limitations in vascular systems. Med Thoracalis 1962; 19: 224-38.
14. Agarwal JB, Paltoo R, Palmer WH. Relative viscosity of blood at varying hematocrits in pulmonary circulation. J Appl Physiol 1970; 29: 866-71.
15. Hall TS. The pathophysiology of cardiopulmonary bypass. The risks and benefits of hemodilution. Chest 1995; 107: 1125-33.
16. Urzua J, Troncosco S, Bugedo G et al. Renal function and cardiopulmonary bypass: effect of perfusion pressure. J Cardiothorac Vasc Anesth 1992; 6: 299-303.
17. Casellas D, Mimran A. Shunting in renal microvasculature of the rat: a scanning electron microscopic study of corrosion casts. Anat Rec 1981; 201: 237-48.
18. Migdal S, Alexander EA, Bruns FJ, Riley AL, Levinsky NG. Effect of hemodilution on the distribution of renal blood flow. Circ Res 1975; 36: 71-75.
19. Nashat P. Effects of changes in hematocrit on renal function. J Physiol 1967; 193: 513-22.