Calibration and LOD/LOQ estimation of a chemilumenescent hybridization assay for residual DNA in recombinant protein drugs expressed in E. coli using a four-parameter logistic model

Drug Development and Industrial Pharmacy

Volumn 26, Issue 6, 2000, Pages 661-669

  Lee, Kwan R ^a   Dipaolo, Byron ^a   Ji, Xiaoying ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

Author keywords

Calibration; Chemiluminescent hybridization assay; Limit of detection; Limit of quantitation

Indexed keywords

RECOMBINANT PROTEIN;

ARTICLE; CALCULATION; CALIBRATION; ENZYME LINKED IMMUNOSORBENT ASSAY; HYBRIDIZATION; IMMUNOASSAY; RADIOACTIVITY; RADIOIMMUNOASSAY; REFERENCE VALUE;

CALIBRATION; CHEMILUMINESCENT MEASUREMENTS; CLONING, MOLECULAR; DNA PROBES; DNA, BACTERIAL; DNA, RECOMBINANT; ENZYME-LINKED IMMUNOSORBENT ASSAY; ESCHERICHIA COLI; MODELS, BIOLOGICAL; NUCLEIC ACID HYBRIDIZATION; RADIOIMMUNOASSAY; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS;

EID: 0034077197     PISSN: 03639045     EISSN: None     Source Type: Journal    
DOI: 10.1081/DDC-100101281     Document Type: Article

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