Effect of phosphocholine cytidylyltransferase overexpression on phosphatidylcholine synthesis in alveolar type II cells and related cell lines

American Journal of Respiratory Cell and Molecular Biology

Volumn 22, Issue 1, 2000, Pages 116-124

  Spragg, Roger G ^a   Li, Jiali ^a  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALIA;

EID: 0034076976     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/ajrcmb.22.1.3295     Document Type: Article

References (33)

1. 1. Mallampalli, R. K., R. G. Salome, S. L. Bowen, and D. A. Chappell. 1997. Very low density lipoproteins stimulate surfactant lipid synthesis in vitro. J. Clin. Invest. 99:2020-2029.
2. 2. Van Golde, L. M. G., and C. Casals. 1991. Metabolism of lipids. In The Lung: Scientific Foundations. R. G. Crystal and J. B. West, editors. Raven Press, Ltd., New York. 25-31.
3. 3. Possmayer, F. 1990. Metabolism of phosphatidylcholine in lung. In Phosphatidylcholine Metabolism. D. E. Vance, editor. CRC Press, Boca Raton, FL. 205-223.
4. 4. Post, M., J. J. Batenburg, B. T. Smith, and L. M. Van Golde. 1984. Pool sizes of precursors for phosphatidylcholine formation in adult rat lung type II cells. Biochim. Biophys. Acta 795:552-557.
5. 5. Tokmakjian, S., D. S. Haines, and F. Possmayer. 1981. Pulmonary phosphatidylcholine biosynthesis: alterations in the pool sizes of choline and choline derivatives in rabbit fetal lung during development. Biochim. Biophys. Acta 663:557-568.
6. 6. Possmayer, F., P. G. Casola, F. Chan, P. MacDonald, M. A. Ormseth, T. Wong, P. G. Harding, and S. Tokmakjian. 1981. Hormonal induction of pulmonary maturation in the rabbit fetus: effects of maternal treatment with estradiol-17 beta on the endogenous levels of cholinephosphate, CDP-choline and phosphatidylcholine. Biochim. Biophys. Acta 664:10-21.
7. 7. Chan, F., P. G. Harding, T. Wong, G. F. Fellows, and F. Possmayer. 1983. Cellular distribution of enzymes involved in phosphatidylcholine synthesis in developing rat lung. Can. J. Biochem. Cell Biol. 61:107-114.
8. 8. Kalmar, G. B., R. J. Kay, A. C. LaChance, and R. B. Cornell. 1994. Primary structure and expression of a human CTP:phosphocholine cytidylyltransferase. Biochim. Biophys. Acta 1219:328-334.
9. 9. Kalmar, G. B., R. J. Kay, A. Lachance, R. Aebersold, and R. B. Cornell. 1990. Cloning and expression of rat liver CTP:phosphocholine cytidylyltransferase: an amphipathic protein that controls phosphatidylcholine synthesis. Proc. Natl. Acad. Sci. USA 87:6029-6033.
10. 10. Tang, W., G. A. Keesler, and I. Tabas. 1997. The structure of the gene for murine CTP:phosphocholine cytidylyltransferase. Ctpct: relationship of exon structure to functional domains and identification of transcriptional start sites and potential upstream regulatory elements. J. Biol. Chem. 272:13146-13151.
11. 11. Wang, Y., J. I. MacDonald, and C. Kent. 1993. Regulation of CTP:phosphocholine cytidylyltransferase in HeLa cells: effect of oleate on phosphorylation and intracellular localization. J. Biol. Chem. 268:5512-5518.
12. 12. Weinhold, P. A., M. E. Rounsifer, S. E. Williams, P. G. Brubaker, and D. A. Feldman. 1984. CTP:phosphocholine cytidylyltransferase in rat lung: the effect of free fatty acids on the translocation of activity between microsomes and cytosol. J. Biol. Chem. 259:10315-10321.
13. 13. Walkey, C. J., G. B. Kalmar, and R. B. Cornell. 1994. Overexpression of rat liver CTP:phosphocholine cytidylyltransferase accelerates phosphatidylcholine synthesis and degradation. J. Biol. Chem. 269:5742-5749.
14. 14. Mallampalli, R. K., R. G. Salome, and A. A. Spector. 1994. Regulation of CTP:choline-phosphate cytidylyltransferase by polyunsaturated n-3 fatty acids. Am. J. Physiol. 267:L641-L648.
15. 15. Shiratori, Y., A. K. Okwu, and I. Tabas. 1994. Free cholesterol loading of macrophages stimulates phosphatidylcholine biosynthesis and up-regulation of CTP:phosphocholine cytidylyltransferase. J. Biol. Chem. 269:11337-11348.
16. 16. Mallampalli, R. K., S. N. Mathur, L. J. Warnock, R. G. Salome, G. W. Hunninghake, and F. J. Field. 1996. Betamethasone modulation of sphingomyclin hydrolysis up-regulates CTP:cholinephosphate cytidylyltransferase activity in adult rat lung. Biochem. J. 318:333-341.
17. 17. Dobbs, L. G., R. Gonzalez, and M. C. Williams. 1986. An improved method for isolating type II cells in high yield and purity. Am. Rev. Respir. Dis. 134: 141-145.
18. 18. Sanes, J. R., J. L. Rubenstein, and J. F. Nicolas, 1986. Use of a recombinant retrovirus to study post-implantation cell lineage in mouse embryos. EMBO J. 5:3133-3142.
19. 19. Burkhardt, R., W. P. Von, J. J. Batenburg, and G. L. Van. 1988. Fatty acids stimulate phosphatidylcholine synthesis and CTP:choline-phosphate cytidylyltransferase in type II pneumocytes isolated from adult rat lung. Biochem. J. 254:495-500.
20. 20. Chander, A., and A. B. Fisher. 1988. Choline-phosphate cytidyltransferase activity and phosphatidylcholine synthesis in rat granular pneumocytes are increased with exogenous fatty acids. Biochim. Biophys. Acta 958:343-351.
21. 21. Weinhold, P. A., M. E. Rounsifer, L. Charles, and D. A. Feldman. 1989. Characterization of cytosolic forms of CTP:choline-phosphate cytidylyltransferase in lung, isolated alveolar type II cells, A549 cells and Hep G2 cells. Biochim. Biophys. Acta 1006:299-310.
22. 22. Bligh. E. G., and W. J. Dyer. 1959. A rapid method of total lipid extraction and purification. Can. J. Biochem. Physiol. 37:911-917.
23. 23. Mason, R. J., J. Nellenbogen, and J. A. Clements. 1976. Isolation of disaturated phosphatidylcholine with osmium tetroxide. J. Lipid Res. 17:281-284.
24. 24. Speirs, V., K. P. Ray, and R. I. Freshney. 1991. Paracrine control of differentiation in the alveolar carcinoma, A549, by human foetal lung fibroblasts. Br. J. Cancer 64:693-699.
25. 25. Mason, R. J., and M. C. William. 1980. Phospholipid composition and ultrastructure of A549 cells and other cultured pulmonary epithelial cells of presumed type II cell origin. Biochim. Biophys. Acta 617:36-50.
26. 26. Hogan, M., L. J. Zimmermann, J. Wang, M. Kuliszewski, J. Liu, and M. Post. 1994. Increased expression of CTP:phosphocholine cytidylyltransferase in maturing type II cells. Am. J. Physiol. 267:L25-L32.
27. 27. Planer, B. C., Y. Ning, S. A. Kumar, and P. L. Ballard. 1997. Transcriptional regulation of surfactant proteins SP-A and SP-B by phorbol ester. Biochim. Biophys. Acta 1353:171-179.
28. 28. George, T. N., and J. M. Snyder. 1997. Regulation of surfactant protein gene expression by relinoic acid metabolites. Pediatr. Res. 41:692-701.
29. 29. Kalina, M., R. J. Mason, and J. M. Shannon. 1992. Surfactant protein C is expressed in alveolar type II cells but not in Clara cells of rat lung. Am. J. Respir. Cell Mol. Biol. 6:594-600.
30. 30. Post, M., J. J. Batenburg, and L. M. Van Golde. 1980. Effects of cortisol and thyroxine on phosphatidylcholine and phosphatidylglycerol synthesis by adult rat lung alveolar type II cells in primary culture. Biochim. Biophys. Acta 618:308-317.
31. 31. Viscardi, R. M., P. A. Weinhold, T. M. Beals, and R. H. Simon. 1989. Cholinephosphate cytidylyltransferase in fetal rat lung cells: activity and subcellular distribution in response to dexamethasone. Exp. Lung Res. 15:223-237.
32. 32. Gregory, T. J., K. P. Steinberg, R. Spragg, J. E. Gadek, T. M. Hyers, W. J. Longmore, M. A. Moxley, G. Z. Cai, R. D. Hite, R. M. Smith, L. D. Hudson, C. Crim, P. Newton, B. R. Mitchell, and A. J. Gold. 1997. Bovine surfactant therapy for patients with acute respiratory distress syndrome. Am. J. Respir. Crit. Care Med. 155:1309-1315.
33. 33. Walmrath, D., A. Gunther, H. A. Ghofrani, R. Schermuly, T. Schneider, F. Grimminger, and W. Seeger. 1996. Bronchoscopic surfactant administration in patients with severe adult respiratory distress syndrome and sepsis. Am. J. Respir. Crit. Care Med. 154:57-62.