Lipase-mediated synthesis of enantiopure N-carbobenzoxy-3-hydroxy- 1,2,3,4-tetrahydro- and N-carbobenzoxy-3-hydroxy-1,2,3,6-tetrahydropyridines from 3-hydroxypyridine

Synthesis

Volumn , Issue 4, 2000, Pages 521-524

  Sakagami, Hideki ^a   Ogasawara, Kunio ^a  

^a TOHOKU UNIVERSITY   (Japan)

Author keywords

Chiral building block; Lipase mediated kinetic resolution; Regioselective reduction; Tetrahydropyridinol; Trans esterification

Indexed keywords

3 HYDROXYPYRIDINE; PYRIDINE DERIVATIVE; TRIACYLGLYCEROL LIPASE;

ARTICLE; CHIRALITY; ENANTIOMER; ESTERIFICATION; REACTION ANALYSIS; SYNTHESIS;

EID: 0034075322     PISSN: 00397881     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2000-6363     Document Type: Article

References (15)

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2. Imanishi, T.; Shin, H.; Hanaoka, M.; Momose, T.; Imanishi, I. Chem. Pharm. Bull. 1982, 30, 3617. Imanishi, T.; Miyashita, K.; Nakai, A.; Inoue, M.; Hanaoka, M. Chem. Pharm. Bull. 1983, 31, 1191.
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7. (c) Sakagami, H.; Samizu, K.; Kamikubo, T.; Ogasawara, K. Synlett 1996, 163.
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